cardiac arrhythmia : CPVT and the Ryanodine Receptor in molecular detail

[dowlingj]

Nice. Flecainide and Propafenone have been identified as drugs that bind to RyR2, preventing arythmmias in most patients with CPVT. I have CPVT and flecainide has changed my life - from triggered VT at 90bpms to no triggered VT, not even VPBs at max pulse. Amazing.

[filipvanpetegem]

@dowlingj It is very encouraging to hear this. There are indeed many promising reports about flecainide. We're hoping to be able to capture a high-resolution structure of flecainide bound to the Ryanodine Receptor in the future, which may help in producing an even more potent alternative.

[alexandrosklavdios]

CPVT1 is characterized by polymorphic type of ventricular arrhythmias, effort-induced that start in a personal heart rate threshold and can lead to sudden cardiac death during effort or emotion

[TheCANSADS]

Prevent Sudden Cardiac Death in the Young. Learn "The Warning Signs" for inherited cardiac rhythm disorders

youtube.com/watch?v=Bi30HxD5sQ­0

youtube.com/user/TheCANSADS

[TheCANSADS]

Prevent Sudden Cardiac Death in the Young. Learn "The Warning Signs" for inherited cardiac rhythm disorders

youtube.com/watch?v=Bi30HxD5sQ­0

[jandee1975]

Tell me something I don't know...

[punchbuggyca]

ABSOLUTELY STUNNING!