ad hominem.. Don't take me not being PC as some sort of implication that I'd be "uncomfortable" having sex with a woman with CAIS. That's ridiculous. I'm just pointing our your flawed logic.
You say "there are many reasons why women can't conceive", but before you made that statement, you said "Her testes don't even produce sperm".
There are many reasons why men can't produce sperm.
Don't you see your double standard? Everything you say about "not being male" I can say about "not being female".
@pastlifewife4 With CAIS, she also does not have fallopian tubes, a cervix, uterus, ovaries, XX chromosomes. She cannot produce sperm, and she also cannot produce an egg.
Everything you say about "not being male" can also be said about her "not being female".
As you say "She has useless testicles" it can also be said "she has a useless vaginal canal".
The rest aren't "typical" female organs because she barely has any except the external structure. All in all she's still a woman but yea..
@DaFawky Your response is correct that she doesn't have the female internal structures to carry a baby. But she was born with external female genitals and developed as a typical female, physically and sexually. There are many reasons why some women can't conceive, this cause not the only one. What I'm sensing from you isn't the issue of genetics, or the lack of a uterus. I sense you are uncomfortable with what her gonads would imply about you if you were attracted to her.
@pastlifewife4 Not at all. Because she has female identity(like almost all ppl with CAIS) and vagina, the medical field deems it "appropriate" to give her the label of female, despite the fact that her sex biologically isn't fully female.(being PC about terminology)
The reason she cant conceive is because of *not* having the traits that makes her female.
Biologically her body isnt fully female or male.
"Female" is just more appropriate for her phenotypical gender role. All have female identity.
If here parents weren't loser and loved her enough to accept her and tell her the truth, she'd be happier. I'd like to punch them. And the dr. People are scared of what's different and what they don't understand.
@Ecka0007 :*take a deep breathe* Androgen Insensitivity Syndrome.Basicly:all fetuses are formed with a female template on the outside(that's why men have nipples XD), at a point the hormones will take actions and the outside sexual organs will differentiate into either a boy's or a girl's.In the case of AIS, somehow a mutation makes the baby insensitive with androgen, and that results in a girl that has a vag and looks like all the other girls,if not prettier,however,has no womb but hidden balls
@uyenst How common is that and is their a test so I won't be decived by one? I don't care what society or even science says, thats too creepy. If my girlfriend told me she had that problem I'd kick her(now him or it) out and try to sue
@ubermisogynist :no it's not common,very rare.Yes it can be tested in a lab with some DNA samples like saliva,hair,blood or a obstetrics or gynaecology clinic.The most simple sign is an adult woman never has periods AT ALL.Wait wait,that kicknsue thing is so ruthless!Surely she didn't choose to be born that way!Don't you love her for anything else except her groin?
No you can't sue an AIS one-9-stand,she didn't rape you,you did it with consent and you didn't ask her "do you have hidden balls?"
@ubermisogynist :And no it's not that bad,think about it this way: If she has a surgery to remove the balls, wouldn't it be awesome?You would have a girl in your dream, she has no acne,no bad smell,no hairy stuffs,very beautiful figure,good height, no period = no "redlight"= nonstop sex without ever worry about her getting pregnant.
@uyenst it's just my world view, people call me bigot,retarded for having that view. I don't care because ultimately I should have right to decide if I don't want to be with someone I don't consider a woman, I don't like someone else deciding that for me. They can do what they want in their own lives but i strongly believe in "your rights end where my nose begin"
Hello i have CAIS and i was looking to do a video about the condition, i have a few people that have AIS of some form who are going to be part of it, if you want to be a part of it just send me a message :D
I don't even know what to say. I was born with the same syndrome (CAIS). I still haven't been able to remove my testes. Feel 100% woman and look 100% like 1. It really depresses me because i cant reproduce children, one of the few things ive always wanted.
0MG THERES S0 MANY PE0PLE LYKE THIS C0MMENTING 0N THIS VIDE0... Y0U GUYS ARE SP0SED T0 BE RARE LMDA0... BUH I THINK U GUYS SHUD ST0P REFFERING T0 Y0URSELVES AS PE0PLE WITH AIS... IT MAKES U S0UND LIKE U HAVE A '' C0NDITI0N '' WHICH CUD BE WHY U 0R 0THERS FEEL AKWARD AB0UT IT... WHEN INFACT U GUYS ARE JUST Y0U GUYS... AND PERFECT AS U ARE... N0 STRANGENESS AB0UT IT ! <3
seriously i am a man. but when my days people keep calling me sissy boy becoz i look like girl and cry like girl. but for a step mom to say that is very hurtful to u. They lied to u becoz they love u. Dont worry they still love u.
@Wolfendale69 No it doesn't. CAIS women like Eden are women born with vaginas. They just happen to have had male chromosomes. They are neither transsexuals nor males therefore this has nothing to do with homosexuality.
@MrNaviWarrior Yes, actually it does! Homosexuality has nothing to do with "transsexuals" either.
Transgender women are women who just happen to be born with penises.
There are tons of other medical conditions that contradict the very meaning of "sex" also.
It really does blow things out the water when there are people who exist in the world who have intersex/transgender conditions. No one can really tell them that they are "being homosexual".
I am an 18 year old girl with ais and I feel and look like a girl but I was luckier than the woman in the video cuz I have a cervix and uterus so I can have a baby just more complicated and I don't have testicles the
Only thing that makes me male is the stupid chromosome
@vikkiXvenom yes i am one. I was told I was born with it when I was 17. I'm now 21. the good thing about it is I don't get acne. Also, like the woman in the video, I can't have children.
and there is the opposite conditions also men who are born malegenitalia with an extra chromosome that would make them super females XXY but they feel like females in most cases and they become transexuals, cause thier brains is female
some people donteven know that is posible....they have breast, hips small waist and little or no facial hair...
If I did not know what an SRS is (sexual reasighnment surgery) I would have comitted suicide already and I weep about this every night of my life, I ask myself "Why the hell did god put me in a males body?!?". I just have to wait a few more depressing years tell I have an SRS and some how manage to tell my parents.
@secretacct0125 be happy hunny, do what u have to do to become what u feel like, i hope God blankets you, and please dont punish yourself u are beautifull as you are..think of this u will never have to deal w/all the periods and menopause like gg women so u are actually blessed
Can't say for sure, but I don't think so-- this is a recognized genetic mutation where the body simply doesn't recognize testosterone and other male hormones. I've never heard of a chemical being linked to it, and think that such a chemical would be banned instantly if it were.
It can be an inherited condition [though people with AIS are sterile, it does run in families] or it can occur spontaneously.
My guess is if there were a chemical known to be causing this, that fact would probably be ignored and or covered up. Just like pesticides being linked to gender bending affects in people. And since so few people have this, its probably "put on the back burner" for fixing. Also what if it was DNA of some or maybe all people altered hundreds or thousands of years ago.
I'm just curious, if there is a greater force in power, if there is a god, what would be the point of this and so many things?
they really didnt explain this condition well. It sounds like they had male chromosomes that were somehow rendered completely irrelevant after they were born. for some reason the body decided to do all the usual female chemical reactions and processes. sounds like the male stuff was only relevant for the creation of testes and then it quit
Genetically male, but completely unaffected by the hormones that cause the development of external genitals and other male traits.
No amount of testoserone therapy would help, because the body of someone with AIS simply doesn't recognize it: there is no lock that the key will fit.
Since they appear female, it's rarely diagnosed until puberty fails to begin.
This comment has received too many negative votesshow
Well, gender sure is a more fluid concept than some people think, that's for sure. I mean if you ask me, she is really a guy, as much as a transsexual who has had SRS is, maybe they are even more a woman than she is because they no longer have testicles. It was only by a disorder that made her external genitalia appear female, she is really not. Physically. But, if you believe, as she said, that sex is a choice and people can be whatever sex they feel like they want to be, then she IS female, ya
If you have a penis and have always thought of yourself as a man, then someone shows up and says 'genetically, you are a woman', would you instantly switch genders for the sake of a molecule you can't even see?
Be greatful you don't have to face that choice!
People with ARS can never be funtionally male, because their bodies don't recognize male hormones. No amount of surgery or hormone therapy will make their bodies match the genes.
I have this exact same defect. I have no female reproductive organs, I had one dormant internal testicle and one semi-active one which caused me to be tall and have a deep voice. I had them removed because I too didn't want to have cancer. Now I don't consider myself to be male or female. I'm intersex
Surgically, it probably would be possible to do as you suggest.
The problem is that a retained testicle has very high odds of becoming cancerous because it's been kept too warm. If a boy of 9 or 10 is discovered to have a retained testicle, it's almost always removed, not shifted into the scrotum.
AIS means they'd never be functionally male anyway, and generaly identify as female since they can't feel the effect of male hormones. So the testicles are removed, female hormones administered.
This comment has received too many negative votesshow
Thank you for that information, I to have no female reproductive organs. I have two, very active testicles, I have a deep voice. I also don't want to have Cancer, but I would most definatly keep my testicle friends. I am male, and the fact that you're "Intersex" fucking freaks me out. Thank you for your time, I'm going to Vomit.
OK... that message i sent was NOT a reply to YouKnowMelmJosh, it was a reply to dalejrfan800. Make sure u check who said what before u comment. I agree with everything YouKnowMelmJosh is saying, i ddnt agree with that derogatory comment dalejrfan800 said.
@rufibrag69 LMDAO...THATS DOPE ! ITS SOMETHING TO BE PROUD OF... I THINK IF ANY OF US CUD BE HALF AND HALF WE WUD LOOOOOL XDD ; AND U SHUD APPLY FOR A PETITION SO THEY ADD A '' INTERSEX '' BOX ON APPLICATION FORMS NEXT TO MALE OR FEMALE.... ;P.. 0MG I L0VE DIS SHxT LOL...
Our culture is so stuck on sex that we insist that EVERYONE has to comply with the standard of either M or F, as they always only have those two boxes. Because of the loss of part of my genitals(circ), my inclination was to mark down "AM"(altered male) instead of "M" as I never felt fully male due to the missing piece.
Hopefully, she obtained the medical records of her birth to confirm it. If what she says is based on what she was told, it is still possible that she is one of the boys who's circ was botched badly and they changed her surgically into a girl. That has happened in the past, and continues today. I know because one of my friends happens to be an OB in OKC. I am brutally aware of the liberties that OB's can and do take on babies that are not "normal" enough for their liking.
I understand what you're saying, lochinvar, but those circumstances always resulted with a very depressed or frustrated child who couldn't comply with the gender role of "female" because they were inherently male. AIS women (including myself) have XY chromosomes, but since we were unresponsive to androgens during fetal development, our bodies- and brains- fell into default formation of female. That's why there are no cases of AIS women who identify as male, unlike other gender disorders.
This might be an accident but I actually once met a person who identified as female to male transsexual and during the process of transitioning, it was found out that she had XY chromosomes. She had PAIS (partial androgene insensitivity), so the testosterone worked for her/now him.
In Europe most transpeople get checked for chromosomal status before they are allowed to transition, and only very few turn out to be intersexual (no more than in general population, I assume).
Im surprised that the reporter failed to mention that even women with XX chromosomes can be infertile for many reasons.
I'm glad this is being out in the open so that that people can have further knowledge about biology and stop saying XX=woman and XY=Man ,because that is all outdated and untrue.
thsi isnt normal infertility, she doesnt have ovaries. she has testicles internaly. so she is incapable of produceing an egg. but she might be capable of somehow producing sperm, though im not sure where it would go.....ive never heard of this condition before unti now..
No she would not be capable of producing sperm. Spermatogensis depends on the effects of testosterone. Even though the testes in AID are fully capable of producing testosterone, her receptors can't respond to it...thus the name of the condition: androgen insensitivity syndrome.
actually, in mammals with testicular feminization (a misnomer, for sure, which is why humans with this condition are termed AIS), spermatogonia are present, they are just immature. I wonder some times if they can be harvested and implanted into some eggs to produce viable embryos.
did the thought that you were replying to an 11 month old comment ever cross yours?...
or perhaps I should rephrase the question in a manner in which you might be able to understand that my point was "nature is not perfect and does not deal in binaries and mutually exclusive dichotomies as society seems to believe",
is that better?
or am i still not politically correct enough for your tastes?
Amazing that presumably well meaning parents thought that a web of lies was somehow less painful than the awkward truth. Nature isn't right or wrong... it just IS... we're the ones who apply the labels. I understand how difficult it is for someone brought up in a seemingly binary world to deal with the ambiguities of untidy reality, but I'm angry that there's any stigma attached to not fitting in to others facile definitions.
i disagree with that to an extent. it is possible to be born a "normal" yy male and have no "abnormal" feminine characteristics at all and see your self as a boy for the first 5 or 10 years of life (not speaking from personal expierence) but not have any strong male role models or influences in your life and be around only women and feminne thinngs for example. or if you are even directly influenced in that direction by people. then you start to "feel" more like a girl.
The idea that someone's internal sense of gender can be changed through conditioning as you describe and that gender identity is primarily learned has been thoroughly discredited.
Google "David Reimer" and you will learn that even with a concerted psychological effort and reinforcement through castration and hormones, you can't make someone's innate male gender identity change.
But what about the people Atwood slept with after learning the truth?
"when the syndrome was formally identified. For Atwood, it was the discovery of that lie that shattered her self-image and drove her to sleep with many men in an effort to prove her femininity."
I think that was wrong. I don't want someone born with internal testicles expecting me to consider them a woman and even worse tricking me into sleeping with them. Should be illegal
We all start out as XX and some some people mutate into XY and those are typically males. Sex determination is a very complex thing, it is a combination of chromosomes, hormones, physical appearance, and self-identification are all factors to sex determination.
Ashley, sex assignment is mostly determined by the chromosomes and the presence or lack of specialised hormone receptors on the cellular surfaces. Your chromosomes are determined by the egg and sperm cells as soon as the spermatozo reaches the egg. A part from the presence of ovaries or testes further sex differentiation doesn't occur until week 8 though.
Of course both of us know gender identity is a completely different matter.
The prescence of intersex people with irregular chromosomes refutes that thesis. Sex differention is still and active field of study and debate in scientific communities.
I'm not sure what you mean by "intersex people with irregular chromosomes". If you mean AIS then it's a case of a mutation on the SRY gene at the X-chromosome, which results in a lack of testosterone sensitivity. In cases of Klinefeldter (XXY) that is an irregularity defined by the irregular chromosomes. If you think about females developing masculine characteristics due to PCOs that's not thought of as intersex. How does that contradict my post?
Androgen insensitivity is caused by a mutation in the gene encoding the androgen receptor. This gene has been shown to display several mutations in its genetic sequence leading to complete androgen insensitivity syndrome (CAIS) to partial insensitivity (PAIS), to no phenotype at all. And the androgen receptor is located intracellularly...i.e., it doesn't exist on the cell surface (steroids are lipophillic, and thus every cellular compartment is available to them).
the statement that "we all start out as XX and some people mutate into XY" is incorrect.
all embryos begin with the complement of sex chromosomes contained in the egg and sperm they are conceived from, usually an X from the mother and either a Y or an X from the father, although other combinations are possible...but whatever they get at conception is what they get .
Phenotypical sex begins in an undifferentiated state and hormones determine if a penis forms, but genotypes don't change.
but then shouldnt hormones determine the formation of a vagina? and i thought hormones dont realy take effect until puberty. and since this girl has internal testicals instad of ovaries, is it possible her chromosomes are xxy?
"Sex" hormone levels don't develop enough to cause adult secondary sexual characteristics like breast and pubic hair growth until puberty, but they absolutely affect people at an embryonic level.
I've never heard of an XXY individual being diagnosed with CAIS, but I don't see any reason why it would be impossible- some XXY individuals are born with ambiguous genitalia.
But in this case they make it clear that testing determined she is XY.
No, sequencing of her DNA would have shown the extra X chromosome...also XXY does not result in female phenotype you see here in AID. XXY also called Klinefelters Sydrome (in case you want to read more) results in small testes and infertility...so you still look male (sorta) but may have breasts, along with a wide range of other symptoms.
Also, hormones don't exactly determine the formation of the vagina. The vagina forms naturally in the absence of testosterone or DHT (hormone responsible for the formation of the penis and scrotum). So if you're XX, you shouldn't have testosterone production and vagina forms. If you're male, that default development is altered into the development of the male external genitalia.
If I remember correctly, during the early weeks of developement, the embryo "swims" in hormones, that cause either male or female physical differentiation. There is another peak of hormones shortly after birth. After that the hormones lie dormant until puberty starts.
The most important thing to understand is the Y chromosome contains a very important gene- SRY (sex determining region of Y); also called TDF (testes determining factor). We all start out with "undifferentiated gonads" that have the potential to become ovaries or testes. Guess what causes the "anlage" to develop into a testis...that's right, SRY. Once formed, the testes begin to release testosterone, "masculinizing" the external genitalia via the androgen receptor. AIS is a mutation in the AR.
An XY chromosome is just a chromosome; I don't get why they have to call it "male DNA"...as a woman with AIS I get a bit offended about idiots who are misinformed thinking that I'm somehow transgendered or something. I'm just like any other woman except for being infertile and not having a period. It depresses me greatly that I'll never be able to get pregnant. Perhaps I'm less of a woman due to my lack of a uterus but that hardly makes me a "man"...my gender identity is 100% female.
So trans women aren't women then? I see little difference between AIS women and trans women. Our condition is just a bit more severe as we develop external masculine features that need to be corrected.
swazia, you are an idiot. She does not have a UTERUS. That is a little different . . . lots of women do not have a uterus, its called a hysterectomy, tardo!
My girlfriend has AIS, and this video highlighted many similarities to what she goes through too. I am glad that AIS has received national attention. The more people know, the less secrecy there will be.
Clear skin, long legs, amply endowed, don't need to shave, don't have to worry about birth control, don't have menstrual cramps(being scraped with a razor inside while you are being microwaved feeling). There are positives. It seems though that people with AIS really want kids (possibly due to the estrogen and lack of testosterone being received). That part is sad. I don't think I agree with removing the gonadal tissue, or at least wait until something can be extracted in case they'll want kids.
The gonadal tissue is essentially worthless in people with AIS. There is no reproductive purpose of the tissues as the "correct" hormones are not received and therefore, no reproductive functions can exist in people with AIS.
if her dna says she's a male then that's what she is. but she is still a woman because that's what she identifies herself as
kendalhart2011 1 month ago
ad hominem.. Don't take me not being PC as some sort of implication that I'd be "uncomfortable" having sex with a woman with CAIS. That's ridiculous. I'm just pointing our your flawed logic.
You say "there are many reasons why women can't conceive", but before you made that statement, you said "Her testes don't even produce sperm".
There are many reasons why men can't produce sperm.
Don't you see your double standard? Everything you say about "not being male" I can say about "not being female".
DaFawky 2 months ago
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DaFawky 2 months ago
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pastlifewife4 4 months ago in playlist pastlifewife4's Favorited Videos
@pastlifewife4 With CAIS, she also does not have fallopian tubes, a cervix, uterus, ovaries, XX chromosomes. She cannot produce sperm, and she also cannot produce an egg.
Everything you say about "not being male" can also be said about her "not being female".
As you say "She has useless testicles" it can also be said "she has a useless vaginal canal".
The rest aren't "typical" female organs because she barely has any except the external structure. All in all she's still a woman but yea..
DaFawky 2 months ago
@DaFawky Your response is correct that she doesn't have the female internal structures to carry a baby. But she was born with external female genitals and developed as a typical female, physically and sexually. There are many reasons why some women can't conceive, this cause not the only one. What I'm sensing from you isn't the issue of genetics, or the lack of a uterus. I sense you are uncomfortable with what her gonads would imply about you if you were attracted to her.
pastlifewife4 2 months ago
@pastlifewife4 Not at all. Because she has female identity(like almost all ppl with CAIS) and vagina, the medical field deems it "appropriate" to give her the label of female, despite the fact that her sex biologically isn't fully female.(being PC about terminology)
The reason she cant conceive is because of *not* having the traits that makes her female.
Biologically her body isnt fully female or male.
"Female" is just more appropriate for her phenotypical gender role. All have female identity.
DaFawky 2 months ago
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pastlifewife4 4 months ago
This means no acne on AIS?
ultimateohmohm 7 months ago
If here parents weren't loser and loved her enough to accept her and tell her the truth, she'd be happier. I'd like to punch them. And the dr. People are scared of what's different and what they don't understand.
gingerisevil02 7 months ago
This video has shined more knowledge about this to me than anything... Thank you!!
gingerisevil02 7 months ago
So can someone explain to me the inverted penis?
gingerisevil02 7 months ago
They should've told her the truth:( the whole sugary thing is heartbreaking! I'd rather be hurt with a lie than not worth the truth.
gingerisevil02 7 months ago
What was that looooooong word?
Ecka0007 11 months ago
@Ecka0007 :*take a deep breathe* Androgen Insensitivity Syndrome.Basicly:all fetuses are formed with a female template on the outside(that's why men have nipples XD), at a point the hormones will take actions and the outside sexual organs will differentiate into either a boy's or a girl's.In the case of AIS, somehow a mutation makes the baby insensitive with androgen, and that results in a girl that has a vag and looks like all the other girls,if not prettier,however,has no womb but hidden balls
uyenst 10 months ago
@uyenst How common is that and is their a test so I won't be decived by one? I don't care what society or even science says, thats too creepy. If my girlfriend told me she had that problem I'd kick her(now him or it) out and try to sue
ubermisogynist 7 months ago
@ubermisogynist :no it's not common,very rare.Yes it can be tested in a lab with some DNA samples like saliva,hair,blood or a obstetrics or gynaecology clinic.The most simple sign is an adult woman never has periods AT ALL.Wait wait,that kicknsue thing is so ruthless!Surely she didn't choose to be born that way!Don't you love her for anything else except her groin?
No you can't sue an AIS one-9-stand,she didn't rape you,you did it with consent and you didn't ask her "do you have hidden balls?"
uyenst 7 months ago
@ubermisogynist :And no it's not that bad,think about it this way: If she has a surgery to remove the balls, wouldn't it be awesome?You would have a girl in your dream, she has no acne,no bad smell,no hairy stuffs,very beautiful figure,good height, no period = no "redlight"= nonstop sex without ever worry about her getting pregnant.
uyenst 7 months ago
@uyenst it's just my world view, people call me bigot,retarded for having that view. I don't care because ultimately I should have right to decide if I don't want to be with someone I don't consider a woman, I don't like someone else deciding that for me. They can do what they want in their own lives but i strongly believe in "your rights end where my nose begin"
ubermisogynist 7 months ago
@ubermisogynist :I think you are right, but if I'm a man I wouldn't mind my girl is a man as long as we love each other. It's about personal views
uyenst 7 months ago
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pastlifewife4 4 months ago
Hello i have CAIS and i was looking to do a video about the condition, i have a few people that have AIS of some form who are going to be part of it, if you want to be a part of it just send me a message :D
imysworld 1 year ago
shes hot all that matters
DemonicSymphonic 1 year ago
I also laugh because i can prove that to be or not to be is not always the case. I wonder if i should let the world know about me and this situation.
sweetlu3206 1 year ago
I don't even know what to say. I was born with the same syndrome (CAIS). I still haven't been able to remove my testes. Feel 100% woman and look 100% like 1. It really depresses me because i cant reproduce children, one of the few things ive always wanted.
sweetlu3206 1 year ago
i dont think i understand anything at all. does she have a pipi?
maxxbarbie 1 year ago
i dont think i understand anything at all
maxxbarbie 1 year ago
Gender is determined more by the brain than the anatomy. There is a self test for brain gender on the BBC web site - well worth taking.
qsfoxx 1 year ago
0MG THERES S0 MANY PE0PLE LYKE THIS C0MMENTING 0N THIS VIDE0... Y0U GUYS ARE SP0SED T0 BE RARE LMDA0... BUH I THINK U GUYS SHUD ST0P REFFERING T0 Y0URSELVES AS PE0PLE WITH AIS... IT MAKES U S0UND LIKE U HAVE A '' C0NDITI0N '' WHICH CUD BE WHY U 0R 0THERS FEEL AKWARD AB0UT IT... WHEN INFACT U GUYS ARE JUST Y0U GUYS... AND PERFECT AS U ARE... N0 STRANGENESS AB0UT IT ! <3
thaOFFICIALJAPAN 1 year ago
seriously i am a man. but when my days people keep calling me sissy boy becoz i look like girl and cry like girl. but for a step mom to say that is very hurtful to u. They lied to u becoz they love u. Dont worry they still love u.
on9hockeu 1 year ago
not to sound to religious but stuff like this pretty much blows to whole theory that God hates homosexuals out of the water.
it's like if he existed he's literally just trying to confuse the hell out of us.
Wolfendale69 1 year ago 6
@Wolfendale69 HE IS TRYING T0 MAKE US REALISE... N0NE 0F THESE CATEG0RIES MATTER... 0UR SPIRITS ARE ALL THE SAME
thaOFFICIALJAPAN 1 year ago
@Wolfendale69 No it doesn't. CAIS women like Eden are women born with vaginas. They just happen to have had male chromosomes. They are neither transsexuals nor males therefore this has nothing to do with homosexuality.
MrNaviWarrior 1 year ago 5
@MrNaviWarrior Yes, actually it does! Homosexuality has nothing to do with "transsexuals" either.
Transgender women are women who just happen to be born with penises.
There are tons of other medical conditions that contradict the very meaning of "sex" also.
It really does blow things out the water when there are people who exist in the world who have intersex/transgender conditions. No one can really tell them that they are "being homosexual".
DaFawky 2 months ago
@Wolfendale69 This is different from homosexuality.
fashionhistorylover 1 year ago
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892lgy7382 1 year ago
women with AIS are typically beautiful and she sure is
babies are by default female anyway so this disorder isnt so strange
tiemedown 1 year ago
You learn new things everyday!!
WOW!!!
ELtercermundista82 1 year ago
I am an 18 year old girl with ais and I feel and look like a girl but I was luckier than the woman in the video cuz I have a cervix and uterus so I can have a baby just more complicated and I don't have testicles the
Only thing that makes me male is the stupid chromosome
reyesyesenia09 1 year ago
ANY AIS GIRLS OUT THERE?
vikkiXvenom 1 year ago
@vikkiXvenom yes i am one. I was told I was born with it when I was 17. I'm now 21. the good thing about it is I don't get acne. Also, like the woman in the video, I can't have children.
fairyravevampire 1 year ago
there is also the opposite side ot this condition men with female chromosomes
its sometimes confused with been a hermaphrodite
GemmaVonTease 1 year ago
and there is the opposite conditions also men who are born malegenitalia with an extra chromosome that would make them super females XXY but they feel like females in most cases and they become transexuals, cause thier brains is female
some people donteven know that is posible....they have breast, hips small waist and little or no facial hair...
GemmaVonTease 1 year ago
WOW
CapitalCruz 1 year ago
If I did not know what an SRS is (sexual reasighnment surgery) I would have comitted suicide already and I weep about this every night of my life, I ask myself "Why the hell did god put me in a males body?!?". I just have to wait a few more depressing years tell I have an SRS and some how manage to tell my parents.
secretacct0125 2 years ago
@secretacct0125 be happy hunny, do what u have to do to become what u feel like, i hope God blankets you, and please dont punish yourself u are beautifull as you are..think of this u will never have to deal w/all the periods and menopause like gg women so u are actually blessed
GemmaVonTease 1 year ago
Very, very good report.
aryanvaryan 2 years ago
i heard about this in physcology we are studying gender. this person does not seem as distressed as transmen, transwomen and intersex people.
ildsc 2 years ago
Also, I have heard that pesticides can cause gender bending affects. Have any chemicals been linked to causing this?
miketonon 2 years ago
Can't say for sure, but I don't think so-- this is a recognized genetic mutation where the body simply doesn't recognize testosterone and other male hormones. I've never heard of a chemical being linked to it, and think that such a chemical would be banned instantly if it were.
It can be an inherited condition [though people with AIS are sterile, it does run in families] or it can occur spontaneously.
Oruboris 2 years ago
My guess is if there were a chemical known to be causing this, that fact would probably be ignored and or covered up. Just like pesticides being linked to gender bending affects in people. And since so few people have this, its probably "put on the back burner" for fixing. Also what if it was DNA of some or maybe all people altered hundreds or thousands of years ago.
I'm just curious, if there is a greater force in power, if there is a god, what would be the point of this and so many things?
miketonon 2 years ago
You could be right, but can you imagine the size of THAT class action lawsuit? It would make asbestos seem like peanuts.
As to your God quesiton, I wish I knew the answer...
Oruboris 2 years ago
Comment removed
krissyeh 2 years ago
miketonon. "Have any chemicals been linked to causing this? ", NO is the answer.
krissyeh 2 years ago
they really didnt explain this condition well. It sounds like they had male chromosomes that were somehow rendered completely irrelevant after they were born. for some reason the body decided to do all the usual female chemical reactions and processes. sounds like the male stuff was only relevant for the creation of testes and then it quit
JustThink00 2 years ago
Comment removed
Oruboris 2 years ago
Genetically male, but completely unaffected by the hormones that cause the development of external genitals and other male traits.
No amount of testoserone therapy would help, because the body of someone with AIS simply doesn't recognize it: there is no lock that the key will fit.
Since they appear female, it's rarely diagnosed until puberty fails to begin.
Oruboris 2 years ago
WHY?
latajohnny 2 years ago
This comment has received too many negative votes show
Well, gender sure is a more fluid concept than some people think, that's for sure. I mean if you ask me, she is really a guy, as much as a transsexual who has had SRS is, maybe they are even more a woman than she is because they no longer have testicles. It was only by a disorder that made her external genitalia appear female, she is really not. Physically. But, if you believe, as she said, that sex is a choice and people can be whatever sex they feel like they want to be, then she IS female, ya
YouKnowMeImJosh 2 years ago
It's more compex than that.
If you have a penis and have always thought of yourself as a man, then someone shows up and says 'genetically, you are a woman', would you instantly switch genders for the sake of a molecule you can't even see?
Be greatful you don't have to face that choice!
People with ARS can never be funtionally male, because their bodies don't recognize male hormones. No amount of surgery or hormone therapy will make their bodies match the genes.
Oruboris 2 years ago
YouKnowMeImJosh. A question for you. Why do males have nipples? Because the default gender for humans is female.
krissyeh 2 years ago
sweeetttttttttttttttt
Lilin1989 2 years ago
I feel really sad that the doctors lied to their patient like that and that parents lied to her. She had a right to know about her own body!
Rubystars1000 2 years ago 2
I have this exact same defect. I have no female reproductive organs, I had one dormant internal testicle and one semi-active one which caused me to be tall and have a deep voice. I had them removed because I too didn't want to have cancer. Now I don't consider myself to be male or female. I'm intersex
rufibrag69 2 years ago 17
Why does that cause cancer?
miketonon 2 years ago
Testicles need to be cooler than the body, that's the whole point of a scrotum. A man with a retained testicle must have it removed too.
Oruboris 2 years ago
But why can't they create a scrotum and move them into it?
Also, why do testicles have to remain cooler than the body? What if they don't?
miketonon 2 years ago
Surgically, it probably would be possible to do as you suggest.
The problem is that a retained testicle has very high odds of becoming cancerous because it's been kept too warm. If a boy of 9 or 10 is discovered to have a retained testicle, it's almost always removed, not shifted into the scrotum.
AIS means they'd never be functionally male anyway, and generaly identify as female since they can't feel the effect of male hormones. So the testicles are removed, female hormones administered.
Oruboris 2 years ago
miketonon, that statement just proves you know nothing about the human body. Here is a question for you. Why do males have nipples?
Because the default gender for humans (and many other mammals) is female.
krissyeh 2 years ago 3
@miketonon The testicles have to remain cooler because that is the right temp. for sperm production.
secretacct0125 2 years ago
This comment has received too many negative votes show
Thank you for that information, I to have no female reproductive organs. I have two, very active testicles, I have a deep voice. I also don't want to have Cancer, but I would most definatly keep my testicle friends. I am male, and the fact that you're "Intersex" fucking freaks me out. Thank you for your time, I'm going to Vomit.
dalejrfan800 2 years ago
and ur the reason why half of America is fucked up.... keep ur narrow-minded comments to urself.
navarronbret15 2 years ago
YouKnowMeImJosh is correct you dipshit.
FWirawr 2 years ago
OK... that message i sent was NOT a reply to YouKnowMelmJosh, it was a reply to dalejrfan800. Make sure u check who said what before u comment. I agree with everything YouKnowMelmJosh is saying, i ddnt agree with that derogatory comment dalejrfan800 said.
navarronbret15 2 years ago
@rufibrag69 LMDAO...THATS DOPE ! ITS SOMETHING TO BE PROUD OF... I THINK IF ANY OF US CUD BE HALF AND HALF WE WUD LOOOOOL XDD ; AND U SHUD APPLY FOR A PETITION SO THEY ADD A '' INTERSEX '' BOX ON APPLICATION FORMS NEXT TO MALE OR FEMALE.... ;P.. 0MG I L0VE DIS SHxT LOL...
thaOFFICIALJAPAN 1 year ago
@rufibrag69 me too! which part of the condition do you have i have CAIS
imysworld 1 year ago
@imysworld same as you
sweetlu3206 1 year ago
@imysworld I have CAIS as well
rufibrag69 1 year ago
@rufibrag69
Nice to meet someone else out there!!! :D
imysworld 1 year ago
dont be sad...the angels in Heaven are neither male nor female..thats in the word of God ...luv u...me
treecee777 2 years ago
Yep!!
woodie62 2 years ago
I think Megan Fox would like to be placed in this category.
joocee102 2 years ago
why
Lilin1989 2 years ago
Our culture is so stuck on sex that we insist that EVERYONE has to comply with the standard of either M or F, as they always only have those two boxes. Because of the loss of part of my genitals(circ), my inclination was to mark down "AM"(altered male) instead of "M" as I never felt fully male due to the missing piece.
lochinvar00465 2 years ago 5
I've decided I'm not ever going to mark those because they are unimportant medical information, and I am not legally obligated to tell them. :P
TuahShinguru 2 years ago 4
Hopefully, she obtained the medical records of her birth to confirm it. If what she says is based on what she was told, it is still possible that she is one of the boys who's circ was botched badly and they changed her surgically into a girl. That has happened in the past, and continues today. I know because one of my friends happens to be an OB in OKC. I am brutally aware of the liberties that OB's can and do take on babies that are not "normal" enough for their liking.
lochinvar00465 2 years ago
I understand what you're saying, lochinvar, but those circumstances always resulted with a very depressed or frustrated child who couldn't comply with the gender role of "female" because they were inherently male. AIS women (including myself) have XY chromosomes, but since we were unresponsive to androgens during fetal development, our bodies- and brains- fell into default formation of female. That's why there are no cases of AIS women who identify as male, unlike other gender disorders.
sarahkinzz 2 years ago 2
This might be an accident but I actually once met a person who identified as female to male transsexual and during the process of transitioning, it was found out that she had XY chromosomes. She had PAIS (partial androgene insensitivity), so the testosterone worked for her/now him.
In Europe most transpeople get checked for chromosomal status before they are allowed to transition, and only very few turn out to be intersexual (no more than in general population, I assume).
spimpernel 2 years ago
This is a very informative video. For that, 5 stars.
somechick73 3 years ago
omg she is gorgeousss!!!
mynamekeisha 3 years ago
Im surprised that the reporter failed to mention that even women with XX chromosomes can be infertile for many reasons.
I'm glad this is being out in the open so that that people can have further knowledge about biology and stop saying XX=woman and XY=Man ,because that is all outdated and untrue.
mulry101 3 years ago
thsi isnt normal infertility, she doesnt have ovaries. she has testicles internaly. so she is incapable of produceing an egg. but she might be capable of somehow producing sperm, though im not sure where it would go.....ive never heard of this condition before unti now..
shadowsa2b 2 years ago
No she would not be capable of producing sperm. Spermatogensis depends on the effects of testosterone. Even though the testes in AID are fully capable of producing testosterone, her receptors can't respond to it...thus the name of the condition: androgen insensitivity syndrome.
erebusnux121 2 years ago
actually, in mammals with testicular feminization (a misnomer, for sure, which is why humans with this condition are termed AIS), spermatogonia are present, they are just immature. I wonder some times if they can be harvested and implanted into some eggs to produce viable embryos.
vancity29 2 years ago
It just goes to show you that nature is alot more fucked up than we give it credit for...
universalJok3r 3 years ago
When you write such a thing, does the thought that people with AIS are reading here never cross your mind?
spimpernel 2 years ago
did the thought that you were replying to an 11 month old comment ever cross yours?...
or perhaps I should rephrase the question in a manner in which you might be able to understand that my point was "nature is not perfect and does not deal in binaries and mutually exclusive dichotomies as society seems to believe",
is that better?
or am i still not politically correct enough for your tastes?
universalJok3r 2 years ago
Amazing that presumably well meaning parents thought that a web of lies was somehow less painful than the awkward truth. Nature isn't right or wrong... it just IS... we're the ones who apply the labels. I understand how difficult it is for someone brought up in a seemingly binary world to deal with the ambiguities of untidy reality, but I'm angry that there's any stigma attached to not fitting in to others facile definitions.
amginena 3 years ago 3
"What determines gender? 'How you feel'"
Truer words were never spoken.
blackmetalqueer 3 years ago 34
i disagree with that to an extent. it is possible to be born a "normal" yy male and have no "abnormal" feminine characteristics at all and see your self as a boy for the first 5 or 10 years of life (not speaking from personal expierence) but not have any strong male role models or influences in your life and be around only women and feminne thinngs for example. or if you are even directly influenced in that direction by people. then you start to "feel" more like a girl.
shadowsa2b 2 years ago
The idea that someone's internal sense of gender can be changed through conditioning as you describe and that gender identity is primarily learned has been thoroughly discredited.
Google "David Reimer" and you will learn that even with a concerted psychological effort and reinforcement through castration and hormones, you can't make someone's innate male gender identity change.
finallytina 2 years ago 2
First, normal male is XY, YY could be fatal.
And secondly, from personal experience, being raised as a boy did not make me one.
blackmetalqueer 2 years ago 6
@blackmetalqueer I like that way of thinking, too.
892lgy7382 1 year ago
@blackmetalqueer
But what about the people Atwood slept with after learning the truth?
"when the syndrome was formally identified. For Atwood, it was the discovery of that lie that shattered her self-image and drove her to sleep with many men in an effort to prove her femininity."
I think that was wrong. I don't want someone born with internal testicles expecting me to consider them a woman and even worse tricking me into sleeping with them. Should be illegal
ubermisogynist 7 months ago
any one interested~ look up the name of the Pediatric Endocrinologist they interviewed
2Peter216 3 years ago
interesting
2Peter216 3 years ago
its true!!!!!!!!!!!!!!!!
junksmasher777 3 years ago
Not clear enough.
I understand about the xy chromosome, but what about hormones...??
And I always thought that as embryos, we are all the same sex and that the hormones either construct the sex organ cells into male or female types.
So would an AIS woman have sperm?
And is there such a thing as a man that is XY instead of XX?
JohnnyRock2000 3 years ago 2
We all start out as XX and some some people mutate into XY and those are typically males. Sex determination is a very complex thing, it is a combination of chromosomes, hormones, physical appearance, and self-identification are all factors to sex determination.
icecoldbath 3 years ago
Ashley, sex assignment is mostly determined by the chromosomes and the presence or lack of specialised hormone receptors on the cellular surfaces. Your chromosomes are determined by the egg and sperm cells as soon as the spermatozo reaches the egg. A part from the presence of ovaries or testes further sex differentiation doesn't occur until week 8 though.
Of course both of us know gender identity is a completely different matter.
TenderGenderBender 3 years ago
The prescence of intersex people with irregular chromosomes refutes that thesis. Sex differention is still and active field of study and debate in scientific communities.
icecoldbath 3 years ago
Ashley are you thinking of a specific condition?
I'm not sure what you mean by "intersex people with irregular chromosomes". If you mean AIS then it's a case of a mutation on the SRY gene at the X-chromosome, which results in a lack of testosterone sensitivity. In cases of Klinefeldter (XXY) that is an irregularity defined by the irregular chromosomes. If you think about females developing masculine characteristics due to PCOs that's not thought of as intersex. How does that contradict my post?
TenderGenderBender 3 years ago
Androgen insensitivity is caused by a mutation in the gene encoding the androgen receptor. This gene has been shown to display several mutations in its genetic sequence leading to complete androgen insensitivity syndrome (CAIS) to partial insensitivity (PAIS), to no phenotype at all. And the androgen receptor is located intracellularly...i.e., it doesn't exist on the cell surface (steroids are lipophillic, and thus every cellular compartment is available to them).
vancity29 2 years ago
You're right the receptors are intracellular. Thanks for pointing that out.
TenderGenderBender 2 years ago
the statement that "we all start out as XX and some people mutate into XY" is incorrect.
all embryos begin with the complement of sex chromosomes contained in the egg and sperm they are conceived from, usually an X from the mother and either a Y or an X from the father, although other combinations are possible...but whatever they get at conception is what they get .
Phenotypical sex begins in an undifferentiated state and hormones determine if a penis forms, but genotypes don't change.
finallytina 2 years ago
but then shouldnt hormones determine the formation of a vagina? and i thought hormones dont realy take effect until puberty. and since this girl has internal testicals instad of ovaries, is it possible her chromosomes are xxy?
shadowsa2b 2 years ago
"Sex" hormone levels don't develop enough to cause adult secondary sexual characteristics like breast and pubic hair growth until puberty, but they absolutely affect people at an embryonic level.
I've never heard of an XXY individual being diagnosed with CAIS, but I don't see any reason why it would be impossible- some XXY individuals are born with ambiguous genitalia.
But in this case they make it clear that testing determined she is XY.
finallytina 2 years ago
No, sequencing of her DNA would have shown the extra X chromosome...also XXY does not result in female phenotype you see here in AID. XXY also called Klinefelters Sydrome (in case you want to read more) results in small testes and infertility...so you still look male (sorta) but may have breasts, along with a wide range of other symptoms.
erebusnux121 2 years ago
Also, hormones don't exactly determine the formation of the vagina. The vagina forms naturally in the absence of testosterone or DHT (hormone responsible for the formation of the penis and scrotum). So if you're XX, you shouldn't have testosterone production and vagina forms. If you're male, that default development is altered into the development of the male external genitalia.
erebusnux121 2 years ago
If I remember correctly, during the early weeks of developement, the embryo "swims" in hormones, that cause either male or female physical differentiation. There is another peak of hormones shortly after birth. After that the hormones lie dormant until puberty starts.
spimpernel 2 years ago
very complicated and it is obviously too complicated for you.
vancity29 2 years ago
The most important thing to understand is the Y chromosome contains a very important gene- SRY (sex determining region of Y); also called TDF (testes determining factor). We all start out with "undifferentiated gonads" that have the potential to become ovaries or testes. Guess what causes the "anlage" to develop into a testis...that's right, SRY. Once formed, the testes begin to release testosterone, "masculinizing" the external genitalia via the androgen receptor. AIS is a mutation in the AR.
vancity29 2 years ago
An XY chromosome is just a chromosome; I don't get why they have to call it "male DNA"...as a woman with AIS I get a bit offended about idiots who are misinformed thinking that I'm somehow transgendered or something. I'm just like any other woman except for being infertile and not having a period. It depresses me greatly that I'll never be able to get pregnant. Perhaps I'm less of a woman due to my lack of a uterus but that hardly makes me a "man"...my gender identity is 100% female.
enigmatically 3 years ago
So trans women aren't women then? I see little difference between AIS women and trans women. Our condition is just a bit more severe as we develop external masculine features that need to be corrected.
icecoldbath 3 years ago 2
"So trans women aren't women then?"
I didn't say that. I don't have a problem with transwomen. Sorry if what I said was offensive to you; it wasn't intended to be.
enigmatically 3 years ago
it is horrable that they lied to her. People should live the way they want. every one should be treated with respect. Eden your rock.
shortcutebutch 3 years ago 3
This has been flagged as spam show
so they saying she dont have a pussy uhhh nasty
swazia73 3 years ago
This comment has received too many negative votes show
they say she has a pussy but that she is different from other mowen is male DNA.
phuditpuangmalai 3 years ago
swazia, you are an idiot. She does not have a UTERUS. That is a little different . . . lots of women do not have a uterus, its called a hysterectomy, tardo!
nltate 3 years ago
i didnt know, you live and you learn
swazia73 3 years ago
My girlfriend has AIS, and this video highlighted many similarities to what she goes through too. I am glad that AIS has received national attention. The more people know, the less secrecy there will be.
Peacegirl85 3 years ago 5
Clear skin, long legs, amply endowed, don't need to shave, don't have to worry about birth control, don't have menstrual cramps(being scraped with a razor inside while you are being microwaved feeling). There are positives. It seems though that people with AIS really want kids (possibly due to the estrogen and lack of testosterone being received). That part is sad. I don't think I agree with removing the gonadal tissue, or at least wait until something can be extracted in case they'll want kids.
lostindreams3 3 years ago 2
The gonadal tissue is essentially worthless in people with AIS. There is no reproductive purpose of the tissues as the "correct" hormones are not received and therefore, no reproductive functions can exist in people with AIS.
Peacegirl85 3 years ago
wow.... she ... is very beautiful..
ThankYouFairy 3 years ago 3
The bottom line is that she is a she. That's her gender identity, and that's the most important thing.
AndrogyneMichinaga 3 years ago 6