remember guys, telomeres are added in replication by telomerases, 5'cap and the 3'polyadenylation is added to the the transcripted mRNA before it is sent out of the nucleus. Basicly to protect it and make it recognizable for the rRNA subunits
Fantastic! I was watch loads of videos for simpler way of explaining the DNA Replication and they made it difficult to understand. This has to be the most simple and best video I've watched so far. Awesome!!!
Stem cells, germ line cells, and cancer cells all have active telomerase allowing them to replicate infinitely, this is why we age, because our somatic cells do not have this RNA dependent DNA polymerase (telomerase) activated. Since we cannot extend our telomeres in somatic cells some of the telomere is lost upon each replication in that cell line to the point where our telomeres are so short that DNA errors begin to occur. Shorter telomeres = more DNA errors + harder to correct those errors
I have to think of complex things like DNA or even World War 1 as having seperate components that are people (like the nucleotides are people and the hydrogen bonds are different people) and my teachers don't understand that but this really helped me get this down! Thanks so much!
This is Bio AP? I am a 9th grader in California and this pretty much summarizes DNA replication in my biology honors class. Thanks for making it look simpler and easier to understand because my teacher gave us quick notes on this without explaining thoroughly! It wasn't even in my textbook!
@flippergibbit So glad we could help! That's why we create our curriculum, because it's easier for many students to watch videos and learn. We get these great professors to teach so that it's more fun and engaging!
Oh, that's why the telomeres get shorter as we age. So when the telomeres are exhausted we pretty much reach the end of our rope and expire or at least start to:-) ??? Great video series.
You are the MAN. You literally summarized 10 pages of my textbook and 6 pages of powerpoint outlines in a few minutes. Why don't you teach Intro Bio at Fordham University?
SO Confused im only in 8th grade im like WTF.
imakickurass1000 1 day ago in playlist Science
More videos please :)
zai4booc 2 weeks ago
You saved me!!! You should come teach at UTA! Thank so much Professor I could just hug you! XOXO
nursingclassof2009 2 months ago
I'm pretty sure Professor Wolfe invented being cool.
Dkc3 2 months ago
i want to commit apoptosis.
migglep 4 months ago 2
remember guys, telomeres are added in replication by telomerases, 5'cap and the 3'polyadenylation is added to the the transcripted mRNA before it is sent out of the nucleus. Basicly to protect it and make it recognizable for the rRNA subunits
qrais 4 months ago
Great video, congratulations. It makes something elaborate look like basic stuff. Again, congratulatios.
eduardo19922009 8 months ago
I can't find a word to describe how amazing he is =D
HFN1211 8 months ago
I'm still confused but it's a lot clearer than it was before.
Thank you!
XanderBBo 9 months ago
Fantastic! I was watch loads of videos for simpler way of explaining the DNA Replication and they made it difficult to understand. This has to be the most simple and best video I've watched so far. Awesome!!!
deathclaw492 9 months ago
why is he bold???
mustanghmt 10 months ago
@mustanghmt Not sure what you are asking here...
ThinkwellVids 9 months ago 4
@ThinkwellVids I think he misspelled "bald" (his bad attempt at humor.)
Luke2kz71 9 months ago
@Luke2kz71 ah.. gotcha. Most likely Prof. Wolfe was being silly as he loves to inject humor into his lectures. :)
ThinkwellVids 9 months ago
Stem cells, germ line cells, and cancer cells all have active telomerase allowing them to replicate infinitely, this is why we age, because our somatic cells do not have this RNA dependent DNA polymerase (telomerase) activated. Since we cannot extend our telomeres in somatic cells some of the telomere is lost upon each replication in that cell line to the point where our telomeres are so short that DNA errors begin to occur. Shorter telomeres = more DNA errors + harder to correct those errors
jphish12 10 months ago
I have to think of complex things like DNA or even World War 1 as having seperate components that are people (like the nucleotides are people and the hydrogen bonds are different people) and my teachers don't understand that but this really helped me get this down! Thanks so much!
happyrhodesful 11 months ago
You are the best teacher ever!!! That helped so much thanks!!
Kaytykat123 1 year ago
Thank you so so so much! I have a big ap bio test tomorrow and I feel so prepared after watching this! Thanks again!
missallieweasley 1 year ago
OMGOMGOMGOMG i love you.. i understand !!!!!!!
RiCETOOB 1 year ago
This is Bio AP? I am a 9th grader in California and this pretty much summarizes DNA replication in my biology honors class. Thanks for making it look simpler and easier to understand because my teacher gave us quick notes on this without explaining thoroughly! It wasn't even in my textbook!
flippergibbit 1 year ago 2
@flippergibbit So glad we could help! That's why we create our curriculum, because it's easier for many students to watch videos and learn. We get these great professors to teach so that it's more fun and engaging!
ThinkwellVids 1 year ago
Enthusiasm is your gift! "Put those babies on there..."
I am into it!
Thanks!
MsGrammarnazi 1 year ago
Comment removed
MsGrammarnazi 1 year ago
SIr ur an awesome professor.......i really wish, u could be my teacher....thank u very much for helping students like us..........................
SharoonKhalid 1 year ago
this contains all the contents of AP BIO??? I´m making fan of this videos!!
This teacher is AWESOME !! really THANK YOUU
Angelwings121 1 year ago
the dr phil of biology
imnotELLIINyou 1 year ago 5
@imnotELLIINyou AHAHAHAHAHA!!!!!!! omg
RiCETOOB 1 year ago
missed out uracil
ibsy01 1 year ago
@ibsy01 uracil is for RNA, not DNA...
jkimt08 1 year ago
@jkimt08 thanks still learning so kinda getting confused :L
ibsy01 1 year ago
Oh, that's why the telomeres get shorter as we age. So when the telomeres are exhausted we pretty much reach the end of our rope and expire or at least start to:-) ??? Great video series.
fbt2007 1 year ago
@fbt2007 Glad our video helped explain this to you!!
ThinkwellVids 1 year ago
@ThinkwellVids great video
kissntellen 1 year ago
@kissntellen Cool! Glad you enjoyed it!
ThinkwellVids 1 year ago
@fbt2007
no not really, some cells have telomerases, enzymes that catalyzes the formation of additional telomere sequences
rightbydawn 1 year ago
dam your the Man why can my instructor make it this fun
hotboysyeyo 1 year ago 3
@hotboysyeyo Take our courses and he can be your instructor! :)
ThinkwellVids 1 year ago
this guy is really phenomenal, Thinkwell is lucky to have him
bmxpunker2005 1 year ago
@bmxpunker2005 Yes we are! And he's only one of the many awesome instructors we have!
ThinkwellVids 1 year ago
Thank you for helping me cram for my Bio test tomorrow!
Rockoutloud1994 1 year ago 3
thanks thankssssss !! <3
Bameecutie 1 year ago
that wasn't a nutshell, that was a turtle shell.
Sameer3292 2 years ago 2
Man i learn so much from your videos, u made me understand better than my teacher. please make more videos.
kaykromah 2 years ago 2
True dat Caliabra, he made me understand better than all the 3D-animations!
endorphun 2 years ago
Ok seriously, thank you, I was looking for a good animation on leading and lagging strand, and he explained it better w/ a freakin' picture!
Caliabra 2 years ago 17
im pretty sure the polymerase 3 goes from 5 prime to 3 prime
peteryun1 2 years ago
LOL its true!
DNA polymerase PROOFREADS from 3 prime to 5 prime..and reads from 5 prime to 3 prime..why do I think he said it backwards
somethingcl3v3r 2 years ago
Thank you. You just summed up an entire section of my bio book in less than 3 days. Please make mote videos. :)
TsurugiLover 2 years ago
You are the MAN. You literally summarized 10 pages of my textbook and 6 pages of powerpoint outlines in a few minutes. Why don't you teach Intro Bio at Fordham University?
superior23 2 years ago 23
WOW!! Awesome video! I wish you were my teacher!! ;o)
TheTeinegirl 2 years ago
you are awesome! the video is awesome!
make MORE!!!!!
we need it. haha.
:D
clovepeach 2 years ago
:)
In a nutshell. Big nutshell.
arbyt3r 2 years ago 2