Protein Synthesis: Translation Process

[Theashpratyu]

Thank u !!!!!!!!!!!!!!!!!!!!!!!!$

[etluv]

bet y'all have an exam tomorrow..haha

[cliniquelover97]

omg this makes so much more sense than it did in biology class...THANK U!!!

[kirkferentzrocks]

how does the tRNA know which AA to pick up?

[umiiAfro]

..but where does the tRNA come from?

[umiiAfro]

yheeeeeeeeyyyyyy i get it now

[07cozzy]

Thank you, had to research this for homework, mRNA was easy to understand but before this video tRNA didn't make sense.

Ps. i'm from england, not from an 'American public school'. wanker.

[cjsuljic]

THANK YOU! This makes so much sense now!!!!!

[MrKEKobe]

This video is nice, but a little misleading. The video implies at the end that the stop codon is also a code for the delivery of another amino acid. But the stop codes just stop the process. The stop codes (UAA, UAG, UGA) do not code for the delivery of an amino acid. In the video, the final codon is UGA and if you notice a tRNA still delivers an amino acid. The stop codons simply stop the ribosome from continuing the process.

[Bonelessduckfood]

sry translation but call of duty is just more interesting

[iiwDgiB]

All these kids on here must be in crappy american public schools. My teachers taught everything well. lol

[cliniquelover97]

@iiwDgiB ummm wtf?! i could go on until death telling u about all of the amazing public schools in america. our teachers DO teach well, just some students--like me--prefer to see it visualized so it can make more sense. and correct me if im wrong, but if "all these kids on here must be in crappy american public schools," why are YOU here?

[iiwDgiB]

@cliniquelover97 That's a good question...

[cliniquelover97]

@iiwDgiB LOL

[sibbyzcool]

This is amazing...I was so lost in class. I shall not fail:)

[cheezeydude]

is the rRNA attaching itself to a strand of DNA? or mRNA? the mRNA got the nucleotides from a strand of DNA right? Is all of this happening in a ribosome? IM CONFUSED :'(

[philidelphia96]

@cheezeydude rRNA stands for ribosomal RNA, which is just one of the three different forms of RNA you can have, but this one is designated to be created for the function of a ribosome. So you are right, basically the rRNA is attaching itself to an mRNA (but it is better to just consider rRNA a ribosome for clarification). mRNA came from the DNA. Much like DNA replication, mRNA copied the base pairs from the DNA and the was able to attach to a ribosome.

[cheezeydude]

@philidelphia96 Thank you! this really clarifies things for me! I have a big biology test on Monday. Thanks again!

[1LoveMyDogs]

is it just me or do bio professors make things twice as complicated? i have to look up videos like this to clear it up haha

[aswifttommy]

Brilliant

[SynthetikTV]

i always wonder why teachers can't just do this type of explaining... my teachers always just go straight into the details without explaining the essentials, and it's not always easy to piece things together. gracias.

[Constans69able]

finally someone puts it in simple terms

[ruiraja]

wow mate, thanks, understood everything.

[muawidan]

This is awesome!! Thanks for uploading!

[h1a2n3n4a5h6]

@aZYLuM12891 Probably because it was a chemistry course and you were meant to be on the biology course;)

[generation1313]

@aZYLuM12891 maybe that's because it was a chemistry course, and not a molecular biology course :) just kiddin'...

[sammy3212321]

Then comes along DNA Primase I, I presume?

[mouji1521]

i learned this fully within 1minute and 29 seconds and 2 yrs of biology at college was a waste.

[VanFilmz]

20 jocks disliked this

[Clefentine]

Lol so much easier than my textbook xD

[dinosoureshit]

Bettterrrrr betterrrrrr than my teacher!!!!!!! i got this so easily!!!! man i wish if i have watched this earlier than now ! thxxxxxx for this great video :)

[fras335]

the mRNA doesnt move, the ribosome does

[joestrong21]

@aZYLuM12891 You must be retarted then...

[airwave162]

@aZYLuM12891 I'd hope so....this topic is usually covered in biology/biochem/microbio, not chemistry

[AvanTgardeINT]

this is surely the best video of all other shit videos.

[xblueblaze]

OMg i finally UNDERSTAND!

[jcmzyc]

beautiful

[nayyab2010]

ohhhhhhhhhhhhhhhhhhhhhh thaks a lot !!!!  i can,t tel u how much it help me

[tdnobita]

that animation is wrong! The ribosome has 2 parts, A part and P part. 2 t-RNA still connect the ribosome before they are released and the 2 amino acids are bonded in the ribosome, too. The ribosome in this animation only contains 1 t-RNA and amino acids are bonded outside the ribosome.

[tunisdia]

why the hell are there dislikes?

[saur55]

@tunisdia

they failed their biology quiz on DNA

XD

[JR23BB]

this helps me so much! thanks!

[BibiiGlendana922]

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[flynnuhboi]

Thank you so much my college bio book made it so much harder than it had to be

[sullhann]

I passed my biology test because of this video. Thanks:)

[Fairieswell]

Thanks a lot!

[hmmmmm12]

this helps so much, YOU'RE A GENIUS!! oh video, why can't my professor be more like you?

[SuperSmritee]

hey!! it's ribosome which slides along mRNA no???

[DiscoDiscoGoodGood93]

Dude u have no Idea how much u tought me in a 90 sec video, thanks man although you would probably be dead by now caz this video was made 800 years ago

[rchap95]

My teacher is so terrible. She spent two weeks trying to teach us this and I never understood it until I watched this minute and a half video. THANK YOU

[threee1298]

@rchap95

same

[ToadLicker10]

where do the amino acids on the trna come from

[2000CivicHatch]

OHHHHHHHH....that's how it works

[2000CivicHatch]

Robot voice!

[internettee]

very goood! Under now!

[cody40johnson]

yoo fuuuuckkk thiiiiss shiiiit !

[jakemuch]

oohh i'm so cool because i'm RNA and i don't need thymine or deoxyyribooseee..

[squishy13]

@jakemuch I lol'd :)

[jakemuch]

@squishy13 haha poor biology humour (:

[missgiusto]

Awesome animation. Level of detail is perfect for my high school students. Thanks for posting this!

[davyjee]

17 people cant synthesize protein

[Bubbles0761]

This is a very good and informative video! I have a quiz tomorrow and this has helped me soooooo much!!!!!!!!!!!!!

[luxxiixox]

OHHHHHHHHHHHHHHHHHHH I GET IT NOW!!! THANKYOU!!! I HAVE A TEST 2MORROW AND I MIGHT NOT FAIL NOW THANKYOU!! haha great video, idk why 17 people disliked it -_-

[MsGrammarnazi]

Great video!

[pavender12]

so much better than 80 minutes of my bio teacher. suck it mrs anderson.

[s3anz2]

@pavender12 are you perhaps talking about the Mrs. Anderson who works at WCC?

[shinoe9mp]

this is so clear! ^^

[ajxcman]

super cute

[MrLoool707]

thank you so much

[GLaD0S]

Fuck yeah, RNA!

[laurasp3]

This video is awesome! Thank you so much. Visual representations of complex molecular processes make learning so much easier!

[SStringBean07]

theres two ribosomal subunits, a small and large!! not just one!

[janicetiaaa]

i must be really stupid......... whats the point of all this? and what are we finding?

[SStringBean07]

@janicetiaaa to make amino acids which are the building blocks of proteins... if you don;t know what the importance of proteins are, thats what the whole unit of genetics is about.

[cookiecouturemusic]

lol finally understand it now

[famousmanbearpig]

i got it now!!!

[16TheNumber]

this vid explaind to me what my teach took lik 40 min!!!!

[McTacobell808]

@16TheNumber Lol same here.

[jonoisawitness]

genius :)

[MaxDorval]

Is it me or the information in this video is all weird...

[TheMissBSxx]

OH MY GOOD GOD! I actually get it! YAY thank you

[thelove1177]

thanks a lot for this video.so simple and easy to understand.yeah!

[Cynthiam0917]

Thanks for the video! It helped me understand better about the process.

[Relikboy]

Hhahah Iv been trying to get this process for 3 months, yet all it took for me was to get off my ass youtube it and there we go, all it took was 90 seconds to get something that i couldnt get for 3 months

[devi667]

ohh...  now i get it

[aarebelo5104]

awesome, other professors are always gtryin to confuse you and they do a dam good job at it!!! This guy explained it the way it should be done....

[Actoutlife]

Ahhh HAH! This makes sense now!!!

[helenbobelen]

this video has false information. It is the ribosome that moves, not the mRNA. 

[MIxerzer]

@helenbobelen look at the video again he clearly says the ribrosome moves

[searchin4perfection]

i hav a question here , my teacher told us when the ribosome reaches the stop codon there will be no amino acid but the video didnt say such a thing so help with this plz

[dmha8376]

@searchin4perfection Stop codons do not code for any amino acids (64 amino acids, only 61 coding... because 3 codons are stop codons). The video is wrong: there shouldn't be another aa added on to the chain at the end.

[Thief555WWJD]

THIS IS SO MUCH EASIER TO UNDERSTAND XD I can pass my Biology final now!!

[lalgirl33]

thank you

[duckwrestler510]

ilove this class<333333333333333333333333 rasheeds awesome

[xxxbabyyyy]

T H A N K U S O M U C H !!

[MountArarat7]

beautiful

[chapinwrestler130]

Wow I fucking hate black ppl jk I love everyone word to my jimmies

[2sick4realz]

thank u YouTube cuz tha Biology book wasn't helpin at all

[iansquared3]

tRNA is some weird shit

[bairwavinod]

hhhhhhhhhhhhhhhhhhhhhhhhhhhhhh­

[omgeveryname]

This is Eukaryotic translation as the Initiation was with Methionine and not formylmethionine (as it is in Prokaryotes).

For those wondering:

Initiation phase - the start codon is found (AUG in this case)

Elongation phase - where the amino acids are added in a chain

Termination phase - when the stop codon is detected by release factors (RF)

Good luck :)

[mcmatanmc]

Thank you, I was completely helpless before that!!

[Anuuus]

Ugly

[bermudez951]

The easiest to understand translation so far.

[jeromelim007]

Thanks alot! this really helps :)

[JAMISONS]

Youtube saved my life! Bio is hard, but Youtube is making it easier one step at a time!

[Themer1]

Wow. after all this crap in honors bio this video accomplishes what 2 hours took. wow. damn.

[MrHossen1223]

the video makes the subject protein biosynthesis easier for me.

[poptartsanddrpepper]

Thanks, so helpful! Doesn't it feel good to help others get A's? :)

[chipzandsalsa2]

you guys.

im learning this in 10th grade Honors biology.

your so lucky you got it over with in 7th grade!!

[RockyBalboa211]

@tonyisag: This though is the foundation in which the details can be built upon lol!

[o0Haz30o]

NOW I GET IT!

[darkyoss]

and what might those details be?

[swimmachica]

@darkyoss oops, accidentally gave you a thumbs up

[izayoirose]

OMG! simple and easy to understand! thank u! stupid honors tacher making it sound all difficult and watnot >.>

[McCartney7767TB]

your learning this in honers??? i'm in 7th grade and just finished learning about it!

[izayoirose]

hey, i member learning this in 7th grade and 9th grade! but 11th grade honors make it 10x more difficult and extreme!!! espcial if the class r pretty much college classes! our teacher makes it so difficult to understand wen its actually simple! AGH!

[ColourfulRaiin]

@izayoirose fuking 11th grde teachers

[AnnhilatorPed]

This is hot!

[darkangel2327]

ok but I want to know how tRNA and rRNA forms...anybody knows?

[Theshamham]

@darkangle2327 its not really that important to transcription and translation to know how tRNA and rRNA is formed. rRNA is just ribosomal RNA and makes up the ribosome along with other proteins. tRNA carries the amino acid (on the complementary codon) and has an anti-codon on it that binds to the mRNA's complementary codon, which releases the amino acid.

[00300odyssey]

not enough detail

[rezaeijavan]

MANY THANKS

[EtceteraJemima]

This was unbelievably helpful. I've been going through video after video, and this finally cleared it up.

[iamthechoosen1]

@dottorecannelle care to elaborate?

it sounds pretty right to me

[sussycoco]

lol hsc in 8 hours and im on youtube looking at this HAHA

[jwurm99]

What a legit video very simple

[FireProMMA]

I find it wildly entertaining that I've been studying this for over 4 months and never thought the process looked remotely like this.

[MrBAM1991]

Thank you. This helped me study for my Biology test.

[thinkmanworld]

subhanallah... allah is the creator... make all life in this earth and heaven become reality

[torpedo192]

Damn thats a complicated process.. but ingenious.....and combinations like that create EVERY SINGLE PROTEIN EVER... damn.

[brandowgg]

Wow that made it alot easier..

[Lov3Bass]

mRNA copy the genetic information under RNA polymerase's action => then the copied catene is attached to an tRNA molecule (anticodons+codons) into the rybosomes => results a chain of aminoacids that forms the protein. So simple! Thanks!

[dmhowell256]

very helpful

[shadowknightDD]

Nice video!

[schnepat]

just to help clarify, the mRNA is reading 5'-AUG-3' Because the Transfer molecule is also RNA, it still has antiparallel directionality. So if someone asks whats the anticodon to methionine?

methionine:

5'-AUG-3'

3'-UAC-5' = 5'-CAU-3'

hardest part of these questions is getting the directionality right

[AlexixelA2]

But take it a step further, and find what the original coding sequence in DNA was.

5'-CAU-3"

3'-GTA-5"

So answer is ATG, or 5"-ATG-3"

[ohiostatesteff]

Amazing, I've been starring at my notes for the last hour, and after watching this i finally get what I wrote. Thank you!

[hrdworkincloser]

This was of Great help! Thanks!

[AnimegirlBrasil]

Very Good!!

Thank You!!

[ositoxoxo]

Thanx, esay to understand, execpt for the tRNAs are kinf od big lol. I was expecting the tRNA to be smaller and be covered by the ribosome shwoing the EPA.

THANX

[xjackinlovex]

thanks soooooo much for this video it made the process sooooooooooooo easy to understand!!

[angus24402870451]

Concise and easy to understand.

[DeviousLittleFox]

Thanks for this, I've been finding this tricky to understand when reading about it, but this has made it easier :)

[27melvo]

The stop codon doesnt code for an AA. The stop codon "codes" for a "stop cap" which bonds to the stop codon and when this triplet reaches the A site it stops the process. Hope that helps =)

[jgalvan87]

wow this is so good, they should just replace techears with computers.. GO CELL BIOLOGY... hahaha what a dork

[lisahtk]

def 5 stars

[joeywashere3]

the stop codon doesn't add a amino acid to the chain of amino acids

[topspin1212]

Great! That was really helpful.

[matthaious]

these vids never tell you where the transfer RNA molecules go when they have deposited there amino acids.

[kimmayy]

A translates to U and U is not used, the T translates to A

[pika446]

Awesome!

Really helpful, clear and simple!

[TrucN47]

Sweet and simple

really helped me!

[gizhiz]

I understand!

[muffballs829]

this releay helped on my science project

[RRsoccergirl831]

yes... this is helpful.. but slightly incorrect as you "guitars42" said.. there is no A and P site. Those are very important in understanding protein synthesis. Come on, i'm a freshman in high school... you should know that! lol, its okay.. over.. pretty good video.

[patchmck]

These videos are getting me through college...

You guys who make them kick ass, thanks dudes

[Mauricefeo]

pretty good

[ertreri]

now this a nice clear simple model of protein synthesis.

5 stars.

[guitars42]

Where is the P-site, A-site and E-site at? The tRNA should first bind to the p-site of the large subunit with methionine. The next tRNA binds at the A-site. Then the whole thing should shift so that the two tRNAs occupy the E and P sites and a new tRNA can come in at the empty A site.

[Masteroiece]

whoooa nice thanks

[FatkinsDisease]

this is really useful

[skanky19]

this is a nice simple version of translatio, really good to watch if you wanna get the general idea

[Skylineownage]

thanks!