4) thus, the tubular fluid at the distal convoluted tubule (impermeable to water) is more dilute, (and further diluted by the secondary active reabsorption of Na+ via Na+Cl- cotransport on the luminal surface and Na+K+ atpase on the basolateral surface). and inner medullary interstitum is concentrated.
5) the collecting ducts are permeable to water when aquaporins are opened by ADH. water will flow through these channels and is reabsorbed down a concentration gradient.
2) since cells on the thin descending limb are permeable to water and salt, water leaves and salt enters the tubular fluid by diffusion, equilibrating with the interstitial fluid.
3) the tubular fluid in 1st part of the loop is now more concentrated (as is the interstitium). this fluid now flows to the thick ascending loop where the cycle repeats, multiplying the concentrating effect it has on the interstitium and the thin ascending limb.
1) at the thick ascending limb of the loop of henle, cells are impermeable to water. Na+K+2Cl- pumps are present on the luminal surface of the epithelial cells. This cotransports Na+, K+ and Cl- from the lumen into the cell. At the basolateral membrane, Na+ is transported out of the cell by Na+K+ atpase, K+ and Cl- diffuse out. Thus, medullary interstitium is concentrated and tubular fluid is diluted.
Oh my goodness!! Thank you sooo much! such an easy way for me to understand the whole urine concentration thing! This is a question on my final next week. Thank you, Thank yu
por favor ojala alguin me pueda ayudar que pasa con la persona que dona un rinon en vida cuales son las percusiones o que pasa se puede vivi al 100% ojala alguin me informe mas de este asunto gracias
cramcramcram :)
addtism 3 months ago
hope i am right =X
qwerty112203 9 months ago
4) thus, the tubular fluid at the distal convoluted tubule (impermeable to water) is more dilute, (and further diluted by the secondary active reabsorption of Na+ via Na+Cl- cotransport on the luminal surface and Na+K+ atpase on the basolateral surface). and inner medullary interstitum is concentrated.
5) the collecting ducts are permeable to water when aquaporins are opened by ADH. water will flow through these channels and is reabsorbed down a concentration gradient.
qwerty112203 9 months ago
2) since cells on the thin descending limb are permeable to water and salt, water leaves and salt enters the tubular fluid by diffusion, equilibrating with the interstitial fluid.
3) the tubular fluid in 1st part of the loop is now more concentrated (as is the interstitium). this fluid now flows to the thick ascending loop where the cycle repeats, multiplying the concentrating effect it has on the interstitium and the thin ascending limb.
qwerty112203 9 months ago
@qwerty112203 ,the thin descending limb is only permeable to water as it has aquaporins.but it is not permeable to salts.
Altairroy 6 months ago
Respond to this video...
Altairroy 6 months ago
1) at the thick ascending limb of the loop of henle, cells are impermeable to water. Na+K+2Cl- pumps are present on the luminal surface of the epithelial cells. This cotransports Na+, K+ and Cl- from the lumen into the cell. At the basolateral membrane, Na+ is transported out of the cell by Na+K+ atpase, K+ and Cl- diffuse out. Thus, medullary interstitium is concentrated and tubular fluid is diluted.
qwerty112203 9 months ago
i still don't understand
kelloggcerealxoxo 1 year ago
how will i donwload this video?
dreadfulblood 1 year ago
@dreadfulblood
Fraps it?.. fraps dot com
dippidop 1 year ago
Thank you.
carlandjanet 1 year ago
One of the better video explanations of the counter-current multiplier and its physiological relevance that I've ever seen.
elistener 1 year ago
this video is really helpful-thank u!=D
xaininho 1 year ago
Thanks very helpful
sairawaraich 1 year ago
this is very helpful.. =)
jeane05 1 year ago 2
u made it v simple.thanx
babusha18 1 year ago 2
u made it v simple.thanx
babusha18 1 year ago
cool..........good job !
Astrosparx 1 year ago
thank you
darcysgurl 1 year ago
great video...should have seen that when i was in third year...crying in front of my missy notes! tnx man
WeirdoOwl 2 years ago
hahahaha :)
darcysgurl 1 year ago
hahah I am now in third year (HS anyway) :P
Vjewerica 1 year ago
I Thought it was called counter current because of the opposite direction of blood in the vasa recta.
TheMonicaadame 2 years ago
i need to pee
but that was great
ansarinho 2 years ago 19
nice job... only bad comment is thet u where going just a little to fast for me... ooo well. i finnaly understand it tho.. thanks for ur time
sejastian22 2 years ago
Oh my goodness!! Thank you sooo much! such an easy way for me to understand the whole urine concentration thing! This is a question on my final next week. Thank you, Thank yu
oceanmermaidmaine 2 years ago 3
Ive been trying to understand this for months..and i have externals next week!! this is a life saver!
rollloric 2 years ago 7
Wow thank you so much.
sofrito34 2 years ago
This comment has received too many negative votes show
im lost :(
GayBooi 2 years ago
excellent video, the most complete video that i could find
Chillsy8 2 years ago 2
excellent.
shamzahm 3 years ago
thanks it is cleared explaination of urin formation really thank you alot
alshiani 3 years ago
gooood fantastic vid!
drkauthar 3 years ago 2
This has been flagged as spam show
yeah love it! easier to understand.
drkauthar 3 years ago
fantastic video, really helpful for my exam next week!
laura85elizabeth 3 years ago 2
por favor ojala alguin me pueda ayudar que pasa con la persona que dona un rinon en vida cuales son las percusiones o que pasa se puede vivi al 100% ojala alguin me informe mas de este asunto gracias
oscaralvarez1978 3 years ago
de que me sirve en ingles? u.u
ismagrungesk8 3 years ago
This comment has received too many negative votes show
learn how to speak ion english.... kkkkk
jujubernardo 3 years ago
Thanks, th best i cud find in here. Just what i needed to recap my memory =)
summary:
1. ions excreted at ascending LOH
2. water excreted as a result at descending LOH
3. concentration achieved at medulla. *more ions excreted at ascending, more water excreted at descending
4. salt impenetrable at collecting duct, only water. controlled by aquaporin-2 (ADH/AVP)
shelovedmenot 3 years ago
Good video.
PaigeyAnfield 3 years ago