Added: 4 years ago
From: neurocirujo
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  • cramcramcram :)

  • hope i am right =X

  • 4) thus, the tubular fluid at the distal convoluted tubule (impermeable to water) is more dilute, (and further diluted by the secondary active reabsorption of Na+ via Na+Cl- cotransport on the luminal surface and Na+K+ atpase on the basolateral surface). and inner medullary interstitum is concentrated.

    5) the collecting ducts are permeable to water when aquaporins are opened by ADH. water will flow through these channels and is reabsorbed down a concentration gradient.

  • 2) since cells on the thin descending limb are permeable to water and salt, water leaves and salt enters the tubular fluid by diffusion, equilibrating with the interstitial fluid.

    3) the tubular fluid in 1st part of the loop is now more concentrated (as is the interstitium). this fluid now flows to the thick ascending loop where the cycle repeats, multiplying the concentrating effect it has on the interstitium and the thin ascending limb.

  • @qwerty112203 ,the thin descending limb is only permeable to water as it has aquaporins.but it is not permeable to salts.

  • Respond to this video... 

  • 1) at the thick ascending limb of the loop of henle, cells are impermeable to water. Na+K+2Cl- pumps are present on the luminal surface of the epithelial cells. This cotransports Na+, K+ and Cl- from the lumen into the cell. At the basolateral membrane, Na+ is transported out of the cell by Na+K+ atpase, K+ and Cl- diffuse out. Thus, medullary interstitium is concentrated and tubular fluid is diluted.

  • i still don't understand

  • how will i donwload this video?

  • @dreadfulblood

    Fraps it?.. fraps dot com

  • Thank you.

  • One of the better video explanations of the counter-current multiplier and its physiological relevance that I've ever seen.

  • this video is really helpful-thank u!=D

  • Thanks very helpful

  • this is very helpful.. =)

  • u made it v simple.thanx

  • u made it v simple.thanx

  • cool..........good job !

  • thank you

  • great video...should have seen that when i was in third year...crying in front of my missy notes! tnx man

  • hahahaha :)

  • hahah I am now in third year (HS anyway) :P

  • I Thought it was called counter current because of the opposite direction of blood in the vasa recta.

  • i need to pee

    but that was great

  • nice job... only bad comment is thet u where going just a little to fast for me... ooo well. i finnaly understand it tho.. thanks for ur time

  • Oh my goodness!! Thank you sooo much! such an easy way for me to understand the whole urine concentration thing! This is a question on my final next week. Thank you, Thank yu

  • Ive been trying to understand this for months..and i have externals next week!! this is a life saver!

  • Wow thank you so much.

  • excellent video, the most complete video that i could find

  • excellent.

  • thanks it is cleared explaination of urin formation really thank you alot

  • gooood fantastic vid!

  • fantastic video, really helpful for my exam next week!

  • por favor ojala alguin me pueda ayudar que pasa con la persona que dona un rinon en vida cuales son las percusiones o que pasa se puede vivi al 100% ojala alguin me informe mas de este asunto gracias

  • de que me sirve en ingles? u.u

  • Thanks, th best i cud find in here. Just what i needed to recap my memory =)

    summary:

    1. ions excreted at ascending LOH

    2. water excreted as a result at descending LOH

    3. concentration achieved at medulla. *more ions excreted at ascending, more water excreted at descending

    4. salt impenetrable at collecting duct, only water. controlled by aquaporin-2 (ADH/AVP)

  • Good video.

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