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From: DoesNotFollow
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  • Once the process is complete it undergoes resolution. which means it just cuts the two strands using endonuclease

  • Sorry but a random endonuclease makes the cut if there are no damages and exonuclease degrades the 5' region. Then Rec A guides the single 3' strand to the homologous strand. Then the open loop acts as a template for DNA synthesis since Dna Polymerase cannot synthesize DNA from scratch. Then branch migration occurs and forms a heteroduplex. Then isomerization which makes the double helix twist, starting uncrossed then the intermediate occurs creating a holliday junction and finally crossover.

  • Good, I like that you share this video, I wish success always Homologous Recombination of Double Strand Breaks

  • Nice Video That You Share , So Very Nice Thanks You Homologous Recombination of Double Strand Breaks

  • I Really Like The Video From Your Homologous Recombination of Double Strand Breaks

  • Your Video Is Very Useful Sharing Homologous Recombination of Double Strand Breaks

  • awesome !!!!!! hails

    

  • sick ass video!!!!!!!!!!!!!!!!!! Hi 5!

  • This is useful! :)

  • amazing!! but its exonucleases not endo

  • At sec 36 to 40, r u sure the DNA pol are working from 5'->3' for DNA replication? Just confused! But really thanks for the vid, it's completely helpful. :)

  • exonnuclease not endo :)

  • haha.. so nice;)

  • 0:58 is it me or does that carrier protein loots like a Pup

  • :)

    

  • simply super

  • So helpful and fun!

  • thanks!!

  • Very nice! Thanks for making this.

  • awesome!

  • Would have been better if you used different colors...

  • thank you, thank you, thank you!!!

  • thanks man!

  • great video. I understood DNA recombination.

  • This. Is. Awesome.

  • Thank you! Nice work :)

  • this helped me in my mcb 121 class. thanks! go aggies!

  • This helped me a lot!!

  • excellent job!

  • Good job on this!

  • @jessica409191 Yeah you are right.In fact the direction for the top strand is wrong too.

  • @CASSC However,well done and thanks whoever that took great effort in creating this!

  • Comment removed

  • thanks! :)

  • very nice vid thanks for posting

  • nice way of explaining molecular biology ^^

  • Excellent!!!!!!!!!!!!!! I finally get it!!!

  • this is better than all of the extended reviews! i finally get it... thanks!

  • True, but WOW! Now I understand my cell biology text. Thanks Johnathan.

  • pretty sure everything is correct up until the DNA pol comes in... its swapped shouldn't it be synthesis in the 5 to 3 direction

    the purples should read from 3 to 5 and synthesize from 5 to 3 placing new sequences on the elongating 3" end... (read books until age 35 then write books at 53)

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