Sorry but a random endonuclease makes the cut if there are no damages and exonuclease degrades the 5' region. Then Rec A guides the single 3' strand to the homologous strand. Then the open loop acts as a template for DNA synthesis since Dna Polymerase cannot synthesize DNA from scratch. Then branch migration occurs and forms a heteroduplex. Then isomerization which makes the double helix twist, starting uncrossed then the intermediate occurs creating a holliday junction and finally crossover.
At sec 36 to 40, r u sure the DNA pol are working from 5'->3' for DNA replication? Just confused! But really thanks for the vid, it's completely helpful. :)
pretty sure everything is correct up until the DNA pol comes in... its swapped shouldn't it be synthesis in the 5 to 3 direction
the purples should read from 3 to 5 and synthesize from 5 to 3 placing new sequences on the elongating 3" end... (read books until age 35 then write books at 53)
Once the process is complete it undergoes resolution. which means it just cuts the two strands using endonuclease
joshuavillazana 1 week ago
Sorry but a random endonuclease makes the cut if there are no damages and exonuclease degrades the 5' region. Then Rec A guides the single 3' strand to the homologous strand. Then the open loop acts as a template for DNA synthesis since Dna Polymerase cannot synthesize DNA from scratch. Then branch migration occurs and forms a heteroduplex. Then isomerization which makes the double helix twist, starting uncrossed then the intermediate occurs creating a holliday junction and finally crossover.
joshuavillazana 1 week ago
Good, I like that you share this video, I wish success always Homologous Recombination of Double Strand Breaks
jhoenedu 1 week ago
Nice Video That You Share , So Very Nice Thanks You Homologous Recombination of Double Strand Breaks
jutsmyface 1 week ago
I Really Like The Video From Your Homologous Recombination of Double Strand Breaks
godguetar 1 week ago
Your Video Is Very Useful Sharing Homologous Recombination of Double Strand Breaks
indiage 1 week ago
awesome !!!!!! hails
WaelYakti 1 week ago
sick ass video!!!!!!!!!!!!!!!!!! Hi 5!
shariarahman 3 weeks ago
This is useful! :)
12kwh 3 weeks ago
amazing!! but its exonucleases not endo
m7MD292 1 month ago
At sec 36 to 40, r u sure the DNA pol are working from 5'->3' for DNA replication? Just confused! But really thanks for the vid, it's completely helpful. :)
mtkwan555 1 month ago
exonnuclease not endo :)
Unknown1101 1 month ago
haha.. so nice;)
Blackberrypipe 1 month ago
0:58 is it me or does that carrier protein loots like a Pup
FixerNK 2 months ago
:)
akie787 2 months ago
simply super
skshruthi1 2 months ago
So helpful and fun!
kellyoleary13 2 months ago
thanks!!
100gsun 3 months ago
Very nice! Thanks for making this.
DrTimbo123 3 months ago
awesome!
krnxejl 4 months ago
Would have been better if you used different colors...
Tallturk 4 months ago 2
thank you, thank you, thank you!!!
palumbri 4 months ago
thanks man!
harvard7089 5 months ago
great video. I understood DNA recombination.
kameswaran78 7 months ago
This. Is. Awesome.
Libbiffion 8 months ago
Thank you! Nice work :)
Neumogastric 8 months ago
this helped me in my mcb 121 class. thanks! go aggies!
neeor10 9 months ago
This helped me a lot!!
Rebe16 9 months ago
excellent job!
TheAlexacaius 10 months ago
Good job on this!
skaishroom 10 months ago
@jessica409191 Yeah you are right.In fact the direction for the top strand is wrong too.
CASSC 10 months ago
@CASSC However,well done and thanks whoever that took great effort in creating this!
CASSC 10 months ago
Comment removed
CASSC 10 months ago
thanks! :)
Toxicjazzlove 10 months ago
very nice vid thanks for posting
crambus 1 year ago
nice way of explaining molecular biology ^^
TheFozzygor 1 year ago
Excellent!!!!!!!!!!!!!! I finally get it!!!
AnaLuBlack 1 year ago
this is better than all of the extended reviews! i finally get it... thanks!
Welmoedr 1 year ago
True, but WOW! Now I understand my cell biology text. Thanks Johnathan.
elfbye 1 year ago
pretty sure everything is correct up until the DNA pol comes in... its swapped shouldn't it be synthesis in the 5 to 3 direction
the purples should read from 3 to 5 and synthesize from 5 to 3 placing new sequences on the elongating 3" end... (read books until age 35 then write books at 53)
rocmac18 1 year ago