Paralyzed rat walks again with human Embryonic Stem Cells.

[laurence265]

they always talk about the ethics of using stem cells.. well how ethical is it to have a cure for spine injury and just sit in on the shelf when thousands are depressed and in pain. that's just crazy.

[Waterbro44]

I'm saying this because I have worked in an animal research lab and know how it works. Have I operated on rats? Yes. Did we have to kill them after we were done? Yes. Were they killed humanely? Yes, with CO2 that causes them to simply fall asleep and die peacefully. Why did we kill them post study? It gives us a chance to study the remains and my lab implanted electrodes which would have ultimately led to infection, given enough time. This was a more humane and logical approach.

[Waterbro44]

And as for inhumane treatment of lab animals, each lab in every university has to obey the guidelines established by the Institutional Animal Care and Use Committee (IACUC). Everyone who handles the animals must be certified by the committee to care for the animals. And like I said earlier, it's spinal cord was methodically severed and subsequently repaired by stem cells. Often times labs meticulously record a rat's weight and dietary habits to make sure a procedure hasn't affected it's health.

[Waterbro44]

Guys, are you really asking whether or not the rat injured its back by accident? This rat was part of a study, it's not like they were trying to fix someone's pet. In these types of experiments, they typically sever the spinal cord rendering the rat's hind legs paralyzed. After the injections of stem cells, the neurons regenerate and the rat regains the ability to walk.

As for calling shenanigans....really? This is a study done at Johns Hopkins University. They aren't doing sleight of hand.

[capnhands]

HOW MANY FUCKING YEARS WILL IT BE TILL I WALK AGAIN???

[joalol]

@capnhands probably somewhere around 10-15, if you have the money:)

[HuyWTF510]

So did the mouse injure itself, or did the researcher break its back?

[omglolzbbqsauce]

its two different rats obviously 

[rememberthename33]

@omglolzbbqsauce are you calling shenanigans?

[tonysan168]

We won't even need to use embryonic stem cells to produce this kind of effect... Regular adult stem cells should do fine. So you won't have to worry about killing babies.

[58jtaylor]

Fuck me this is AMAZING!!! Why aren't they doing this on humans yet??

[q1111w]

Religious people are against stem cell research, but they are for hunting

[DemonAMVs]

@q1111w Pretty much, it seems a bundle of 8 human cells is more important then a bundle of billions of animal cells. Then again you kill thousands of cells by scratching your nose, that should be classed as murder :D

[MrFakegods]

They need to get this research on the road!

Makes me sick that all these religious ignorant bastards see this as a bad thing..

.

Think off all the lives it could have saved by now.

I got an idea....

tax the churches.

With that money..

fund stem cell research..

I'm sick of hear about all these old crappy human beings trying to help people by handing out bibles and "spreading the almighty word of god.

Actually read an article about a couple who was killed by pirates off the coast of Somalia .

[BloodPLusFan13]

aw how mean they broke its back at least they helped that cute little rat tho

[BloodPLusFan13]

aw they helped that cute little rat

[kershicat]

Oh, so you guys broke it's spine so you could fix it again? Fucking animal cruelty. Dermatology is the only way. A rat's spine cannot be compared to that of a human.

[adamsquires]

so let me get this straight, your actually admiting to the world that you killed god knows how many little human babys, just to make a rat walk again? this is so evil! jesus didnt kill anyone to heal. he made new eyes from dirt and spit. if you cant find media from dead people leave it alone. dont kill gods children. life starts the instant sperm meets egg. not when a child is born

[maximum411]

@adamsquires

no, what's evil is denying people who are completely paralyzed technology that could potentially restore their quality of life when it is right there. if you were paralyzed you wouldn't be saying it was "against god's will" to heal you. remember, embryos don't have brains or even nerves. they can't think or feel any more than a sperm cell or a bacterium can think or feel.

[AntsPushingFruitLoop]

@adamsquires no one wants to here your preaching. Thanks to science we are where were at. And you can't make new eyes from dirt and spit smart one. And besides embryos can't think or feel until after their brains grow.

[VioletRaynne]

Jesus apparently made a blind man see, well this can make people walk.

[digitalknockout1]

I would pay anything to have this therapy done on my elderly rat who is gradually becoming paralyzed from HED. I wish that vets offered this sort of treatment. I wouldn't care if it cost 2K..if it could give him his mobility back and give quality to his life, that is all that matters. :'(

[shinocicada]

@ussashe I'd be a smartarse and say the obvious, but I'm not a jerk and can tell you're kidding around. XD

[Gethsemaneful]

Since there aren't actual studies supporting embryonic stem cell research and only support adult stem cell research, I suspect that this scientist is only out for money. We don't even know if the rat was actually paralyzed, it could simply have messed up hind legs. This is a pretty biased video.

[fatimmortal]

'MY LEGS! I FEEEEL THEM!!"

[IchiJewSan]

I can see the rat limp alittle but you can still tell it helped so it was successful but not completely.

[miguelmouta]

Can stem cells cure mass culture damage on individuals ? : )

[HeyBubba1992]

@AntiEtc Your comment is unnecessary. It was obviously geared toward my opinions and beliefs to start a debate. I have my opinions and you have yours. Neither of us can state them as if they are facts like you did. Dont try to start pointless arguments, over youtube of all places. Thank you for the half of your comment that was complimenting.

[Venusfading]

@HeyBubba1992 If you insert religion into your comments then it is practically an invitation to have responses like that. Not saying it's right, but seriously....

[Levonanureen]

I honestly don't think that was the same rat....

[Frogster7]

How come the Before Shot Is smaller?

[SCHIZOPHRENlC]

Animal RA-1161... nobody cares.

[EpicFailGirl]

Rats have feelings and bonds, and have many similarities with humans. This is all the more reason they make great test subjects. Seeing as how the rat was helped in this video, this isn't the best place to debate their treatment anyway.

[Sofiarocks776]

yayayaya!! thats so cute. im glad he can walk again

[marsdjinni2]

My rat citrus could have used this to save him :(, maybe someday this will be more widely available as a potential treatment in veterinary medicine.

[shinocicada]

They did help the rat, but in testing a lot of animals are treated terribly.

I wont say it's true, but I wouldn't be surprised if they injured the rat in the first place.

I'm only suspicious because the rat is a lab rat, and I don't see how a lab rat would get a broken back seeing as they're stuck in bins 90% of the time.

Then again, I totally support humane animal testing and when push comes to shove, in most cases, if someone lost the ability to walk, they'd be all for this.

[Benjaaani]

@shinocicada true, and they would have paralysed this rat themselves by detroying motor neurones in it's legs.

[s2716273]

@shinocicada Dude you are honestly nto looking at hte bigger picture. who cares about The rat who has a tiny brain and probablly cannot fully understand fear and doesnt give a shti if its legs are broken as long as it can do its daily activities. This problem of Spinal cord injuries effects thousands of people hundreds of thousands and ruins and wrecks many of their lifes. We need to fix this, not just provide therpay or ways for htem to better live their lifes it must be fixed.

[shinocicada]

@s2716273

I JUST SAID in my comment that I support it if done properly. If you read the last paragraph of what I was saying you'd notice I am looking at the big picture.

But. obviously all, or most animals FEEL fear. That's just instinct, and has nothing to do with brain size and smarts.

Of course it doesn't care though. Unlike humans, rats and non-human animals don't mope around, or complain when they lose their ability to walk, hear, or see. They get on with life.

[withmucheffort]

@s2716273 get real. as a rat owner, they DO care, they CAN feel and it DOES affect how they act. THINK before you speak, or rather, post.

[hydrosav2007]

@shinocicada of course thats the case, most of the time they sedate the animal and do whats called "legion" which is a way for them to destroy very specific parts of the body, i believe with lazer or radiation of some kind, same technique was used to identify different parts of the brain. Im sure the ray doesnt feel any pain, and the cost of hurting or killing a few animals to fix cancer, aids, paralysis, and a hude number of other abnormal cell division is worth it in my book.

[NickBlackDIN]

@shinocicada actually usually lab rats get excellent care, why? because lab rats are cloned )so that they have the same starting point) and cost around $10,000 each, not something they willingly toss away at the slightest whim, plus, they have to make sure the rats all get treated equally

[shinocicada]

@NickBlackDIN I don't doubt rats are kept in suitable conditions. They're very easy to care for. But by animals, I meant all animals they test on. Monkies, rabbits, dogs, ect; they can be treated very very badly.

I'm not saying all, but there's video proof of certain researchers abusing animals.

I'm not saying they're all bad.

[NickBlackDIN]

@shinocicada well you can put your mind at ease about food testing on dogs and cats, I worked in an animal testing facility for ~ 5 years (quit because it's not really my thing) and those dogs and cats get better care then a lot of animals at home, but true, as long as there are things to hurt, there probably being hurt somewhere, but as laws improve (in the states apparently there a lot slacker) so does the animals well being. ^.^

[chacoal]

@shinocicada the lab rat broke his back in a maze twisting and turning. you know they broke its back, but atleast they fixed. feel sorry for the thousands that werent so luck.

[ZygoatVids]

@shinocicada It had motor neurone disease, thats not a broken back. All due respect read it first.

[shinocicada]

@ZygoatVids

Oh, thanks for the confirmation. :)

But, I read the discription, and it didn't say anything about a disease. It said it''s spinal cord was 'Injured'. I've only heard the word 'injury' in the case of someone/thing being hurt, but maybe I missed that information somewhere, or 'injured' was just a bad choice of words. <:/

I do believe you though, because you'd gain nothing from lying. But again, the sentence made it seem like something happened, or was done to the animal.

[ZygoatVids]

@shinocicada Look right at the beginning of the video where its really quite confusing, I may be wrong however but it does look like that.

[shinocicada]

@ZygoatVids That just looks to me like it's only saying what they used to repair it's back.

Because "cell derived motorneurons", which makes me think they took THAT from the stem cells, and gave to the rat to make it walk again.

Hard to explain, but know what I mean?

I could be wrong too, though.

[ZygoatVids]

@shinocicada Well, I'll just stay quiet and mutually agree that theither of us know xD

[shinocicada]

@ZygoatVids XD Reasonable. I agree.

[mrkrabz1991]

@shinocicada they did break its back on purpose, that is why they are called "lab rats"

[shinocicada]

@mrkrabz1991

Well being called a lab rat doesn'tt have anything to do with breaking it's back. XD After all, it isn't called a "Spine-to-be-broken rat".

It could be a legit degenerative disease or something that made it that way. We don't know for sure, which is why I didn't say it was 100%. I just said it was suspiscious.

Unless you've got confirmation? <:I

[mrkrabz1991]

@shinocicada I did just confirm it, this is from the "New Scientist" magazine. They do it for research. Recently, they even cut the heads off of some rats while they were wearing ECG's to test how long you remain concision after decapitation. They wanted to see weather it was humane or not because that is always how they kill lab rats when their done with them. Turns out that you die instantly, but interestingly the brain makes a quick second spike in activity about 30 seconds after death. Hmm..

[DemonAMVs]

@shinocicada You support humane animal testing yet I have never heard of people screaming and protesting in the streets to ban rat and mouse traps which do not kill instantly but break the animals spine to leave them to suffercate, if there spine is not broken there lungs are crushed or starve to death. And your worrying about the what? 1000 rats that could save millions of humans compared to the billions of rats that have killed within the past 20 years probably only 700 humans.

[shinocicada]

@DemonAMVs

How did you get the notion that I think it's okay to kill wild rats and use traps just from my saying I support 'humane' testing?

I don't support traps at all. Especially not glue traps. PLENTLY OF PEOPLE INCLUDING MYSELF boycott them.

I wasn't talking about wild rats because it wasn't RELEVANT TO THE VIDEO. I have commented with deep conviction about them in -other videos- featuring TRAPS.

Why not direct that comment to a person who supports traps instead of me, who doesn't?

[DemonAMVs]

@shinocicada You are dodging the subject, the point was not whether traps are bad or good it was that traps kill more rats inhumanely then animal testing ever will. I don't agree with animal testing for small things like shampoo or things that will not help society very much at all, but for things that can save millions of lives it can be a necessary evil. Without animal testing we would not have vaccines for a quarter of the diseases we have eliminated let alone meds for diabetes and such.

[shinocicada]

@DemonAMVs

I'm not dodging the subject- I simply misunderstood your main point.

I don't support traps, for the reasons you mention. What else needs to be said? I said I agreed with you and I do. I also said in my first post what you said in your two last sentences. Save for the shampoo subject but I agree with you there as well.

I don't understand what you want- we're on the same tip. You came to me with a random fact that I agreed with you on. What exactly are you trying to get from me?

[jdavis52382]

this is TOTALLY wrong... I'm glad the little one walked again, don't get me wrong. but RATS SHOULDN'T BE USED IN LAB TESTING!!!!!!!

[awesomeO807]

A MEN TO THAT

[FLAVICOLE]

@jdavis52382 You know, I am a huge rat lover and have bred and kept rats for 10+years and just got 3 little babies three days ago, but I think that rats have done a great service to society and that they should be shown respect by everyone for all the tests they have had performed on them, some things are just inhumane and acenine but the majority of tests are ok and it just makes me love rats more

[Colinski03]

@jdavis52382 If you were paralyzed you would think differently.

[HeyBubba1992]

I don't see what it is that people have against stem cell research. If god created these things and gave them to us then why is using the periodic table of elements to form new elements not playing god? Cmon- would you rather have your legs or not? I see the research as just finding out one of gods gifts that has been hidden a little bit more than others.

[dennisrayso]

@HeyBubba1992

i agree

why cant Christians be more open minded like you.

[Gundamator]

@HeyBubba1992 People don't have a problem with the cells themselves. It's how they obtain the cells that's the controversy. It's a misrepresentation to say that people are against stem cell research. What they're against is creating life, then killing it to harvest the embryonic stem cells (there are many types of stem cells). Plenty of viable stem cells can be obtained from adults without the need to create a human embryo . Even embryonic stem cells can be obtained without killing an embryo.

[HeyBubba1992]

@Gundamator When i said that i was aware of what it meant. I am aware of the alternative means to gain stem cells. There are scientists who only do this through those means. Although in my opinion, an undeveloped stem cell is, undeveloped and therefor only matter not life. This is again in my opinion. I am of course no scientist and base what I say from what I have read myself and there is always a possibility to be incorrect. If in fact the embryos are conscious humans, then I don't support it.

[Benjaaani]

@Gundamator adult stem cells are not unspecialised completely; they can only form certain tissues, whereas embryonic stem cells are able to form any living tissue

[DyingFetusSkinless]

@HeyBubba1992 ah yes... thank god for abortion....

[HeyBubba1992]

@DyingFetusSkinless I don't really see what abortion has to do with stem cell research. Your on the wrong page. Abortion wasn't something already set forth for us, it doesn't fit into my previous example. That was something fathomed by man that is not supposed to happen. It is considered murder. There are understandable exceptions such as rape... Other than that Its murder.

[DyingFetusSkinless]

@HeyBubba1992 the use dead fetuses for stemcell research

[Forlo12345]

That would be improper science. If they switched the paralyzed rat with a healthy rat, the scientists would be guilty of fraud. No scientist would be stupid enough to catalog this as a medical breakthrough without sufficient data, evidence, and record keeping to back up the finding. Especially if the results are incredible.

Besides, this is a reproducible experiment. Anyone with the right materials and licences could do the same thing (making the results much easier to accept).

[chrisclub]

Animal RA-1161

[Howboutthinking]

I agree I know the possible medical marvel that are stem cells but this does seem fishy

[paperstuffguy]

its more like limping

[menegis]

so? would you rather have no use of your legs or limp? EXACTLY!

[MrTabby5000]

Its moving around better.I know that christopher reeve wouldn't have minded walking with a walker or braces.

If these religious wackos would just leave stem cell research alone and let it happen.

[Aaberg123]

Get an education, read about the scientific method... then post.

[destajista86]

i hope that can help me to with stamcells

[eksdem]

How are the rats doing today?

[LilliHD]

Hey there ... where did you get this video from? How conducted this study? Is there additional information available? Thanks ....