Substance P - Neurology

[FaisalLasiaf1]

At least have some labels so we know whats going on you twat!!!

[SuperNewf1]

Did you now that pain can kill a person irregardless of the originating medical condition that causes the pain?

[Axon36]

@SuperNewf1

Pain can kill?.....how?

[SuperNewf1]

@Axon36 In many ways. Pain causes blood pressure to rise dramatically. People in chronic pain that lasts for months, years, decades, are at high risk. The blood pressure rises in direct proportion to the amount of pain. Also there is a psychological component to pain. Pain will cause depression if it is not treated. Many patients fighting workers compensation claims are committing suicde or dieing of a stress related ilness as a result of not receiving treatment.

[Axon36]

@SuperNewf1

Those are side issues (blood pressure, depression, etc)... pain..per se..can't kill you.

[SuperNewf1]

@Axon36 The problem is, the "side issues" are killing patients because the pain is not being treated.That is murder. What you are saying is like a guy stabs you in the heart but it wasn't the knife that killed him. Who gives a shit. Treat the illness not the side issues. You treat the pain and the depression and blood pressure drops considerably. If you want to treat depression and high blood pressure then treat the cause, and that is pain. Chronic pain that is severe does kill.

[Axon36]

@SuperNewf1

I do..I give more than a shit. Basically you're talking about syndromes as cluster headaches and similar.... among the worst pain than a person can suffer. However, the problem it's not only the cause..but the complexity of the system. Agree....pain can be defeated...but it will take time to understand how and where. Don't worry..we're kicking our own asses trying to resolve that problem.

[SuperNewf1]

@Axon36 I could resolve 90% of pain in a majority of cases. Save their lives doing it. Improve their overall health and sense of well being and security. Return them to work. Identify their needs through assessments of available information. I like your video by the way. It does not matter the source of pain. Cluster headaches are bad, as are migraines. But that pain is intermittent. Chronic neuropathic pain that does not go away, 24/7/365 will drive a man mad if not treated.

[Segma94]

well done, but if you just puted the explanation in the bottom would be perfect.

[XSirApocalypseX]

Well done, but I would make explanations for the elements and molecules.

So also the neurexin and neuroligin. But it's well done with the "Aktionspotential" (I don't know the english word for it, I am Austrian) at the postsynaptic neuron. :)

[CulturePeaceForever]

the sound on this video needs implementation

[Flabnatz]

I like it when the red ones go crazy nuts and then the purple things are like "nom"

[jumb0mumb0]

@Flabnatz

Do you even know what those red and purple things are? I'm clueless as to how 4th graders find these videos!!

[JoyeuxLj]

the yellow is potassium ?

[Creammacker]

very cool, some over casting voice would be nice to be describing exactly whats occurring.

[canadienne99]

thanks ^_____^

[coolerlilipop]

*thanks

[coolerlilipop]

i just wanna ask bout something.

for the neurotransmitter reuptake and propagation of action potential, which occur first?

tanks.

[burninhtd]

the molecules coming into the terminal bulb should be calcium ions, they trigger the exocytosis of the neurotransmitter

[toastyy]

NUH UH. YOU ARE

[ekadzibwa]

send this video to my email adress

[Envyse7enSin]

...A little sound could be nice..

[toastyy]

beep. boop.

[blake350125]

@Envyse7enSin what would you want to hear? you think transmitters make sound o.O

[SamanthaAJones]

I've been checking out your videos. Love the channel. My mother and partner, Cheryl Shuman says that you are a great person and a dear friend. I just started my channel, so I'm sending you a friend request and hope that we can get to know each other. Feel free to contact me.

xoxoox,

Samantha Jones, First Daughter :-)

[danielito2129]

would you mind giving an explanation of this video please?

[zanecha]

Sure. An action potential which was created due to the stimulation of a neuro-receptor, begins to travel down a nerve cell. The action potential travelling down the axon, eventually reaches voltage gated ion channels. If the threshold is surpassed then the ca+ ion chanlles open, causing an influx of ca ions. This causes synaptic vessicles, containing a neurotransmitter to merge with the presynaptic membrance. This results in the release of neurotransmitters into the synaptic cleft.

[zanecha]

The neurotransmitter molecules then bind to specific receptor sites on chemical gated ion channels on the post-synaptic knob. The channels then open. Neurotransmitter is released and is broken down and reused and repackaged back in the pre-synaptic knob. The opened ion channels then allow for an influx of ions (for example's sake, let's say Na+.). If the Na+ causes a large enough change in voltage or the threshold level is reached, then an action potential occurs along the post synaptic knob etc

[marklethanarkle]

a key would have been nice.