@Tl82T a polypeptide (from what i currently know) IS a protein, but depending on its length, and the amino acids in it, and their order, determines the proteins function. to simplify this: depending on how long the thing we see at the end of the video is, and the order of the colors (amino acids) depends on how it acts :D
Quick question. If the large ribosome subunit covers the tRNA and mRNA, how do the other tRNA molecules get in? Do they go through, or is there an opening?
@americanboy717 This is more like a week of molecular biochem, granted we went over every detail, but this 3 mins provided a better summary than my college prof.
Wow. I'm German and I understood it way better than the fucking German texts and pictures we had although I don't understood every word in the video :DD Thank you.
quick question: when the ribosomal subunits are not involved in protein synthesis, do they stay together or drift apart? ooh, and are they held together by their own hydrogen bonding, the nucleotides' hydrogen bonding or something else?
@SiberianHuskyF1 If they are not involved in the Protein Synthesis they'll always be found apart from eachother, so yes, they drift apart after the polypeptide chain is completed. I hope this helps.
ohhhhhhhhhhhhhhhhhhhhhhhhhh...i didnt know there were so many tRNA's used in the process of eleongation. Now i understand the E site(elongaiton)...durrrr, lol
warum gibt es zur trankription und translation so viele erklärungen auf englisch und nur so wenige auf deutsch :-O kann nicht mal einer welche auf deutsch machen bitte? am besten noch heute :-P
Actually, tRNA is transcribed from DNA in the nucleus in a similar fashion to mRNA. In eukaryotes, the major difference in production between the two is that mRNA is transcribed by RNA Polymerase II and tRNA by RNA Pol III.
In addition, for the tRNA to possess its corresponding amino acid necessary for translation to occur, it must first be 'charged' with the amino acid. This process is catalysed by the enzyme aminoacyl tRNA synthetase, which uses ATP to attach the amino acid.
@FlyingGoomba321 The tRNA is assembled by an enzyme known as aminoacyl-tRNA-synthetase and the resulting tRNA molecule is available in the cytosol where it will be needed for translation.
Who needs $300 textbooks when you have this! I couldn't even understand my book, after staring at one sentence for 10 min I gave up. Best decision of the day. By far.
@tugo7 it leaves the cell to go where it is required by the organism. ps. by then it's called a polypeptide, or more accurately, a protein :) a polypeptide is a whole string of peptides that has taken on it's proper 3D shape so it can be functional (just wanted to let you know bc that distinction will come in handy on a MC exam)
This video has one mistake that is apparent. In Eukaryotes, the small ribosomal subunit starts with an intact "charged" tRNA that forms the translation complex. This is different from prokaryotes, where the first tRNA joins the SRS after it has scanned to the start codon.
finally :D an Eukaryotic translation video ! all the rest is prokaryotic translation..
THANK YOU SO MUCH !!
maitokon 4 days ago
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THANK YOU!! THIS IS SO HELPFUL!! I was totally confused and I have a quiz tomorrow but now this cleared all my confusions! :D Thank you!!
SaltySweetSS 5 days ago
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THANK YOU!! THIS IS SO HELPFUL!! I was totally confused and I have a quiz tomorrow but now this cleared all my confusions! :D Thank you!!
SaltySweetSS 5 days ago
THANK YOU!! THIS IS SO HELPFUL!! I was totally confused and I have a quiz tomorrow but now this cleared all my confusions! :D Thank you!!
SaltySweetSS 5 days ago
احا علي الفجر
doctorpoty1 6 days ago
Comment removed
Sluo1947 1 week ago
Great video. Easy, concise and makes sense. I'm going to punch my biology teacher in the face the next time I see him.
StimulateYoMind 1 week ago
good explanation!!! i'm university student and that video help me more then my book
OogiuliettoO 1 week ago
tomorrow my final school examination, called abitur, in biology. your vid rescued me! It's better than every book, articel or pictures.
THANKS :)
unknownuser921026 2 weeks ago
brilliant video very entertaining
desaiproductions93 2 weeks ago 2
Thank you so much! This really helps!! It's difficult to understand when you're just staring at pages of notes!
tiptopluongo 1 month ago 4
Really helpful^^
Littleamericanboxes 1 month ago
When elongation started, all I could think about was how good Mike and Ike's sounded right then... thats what the amino acids remind me of. :)
joyblueeyes118 1 month ago
hey watch it like 5 times, and try playing it in mute, put in your own words what she was saying, that helps me memorize it !
FristOneStoned 1 month ago
thumbs up if your test is tomorrow!
espana9662 1 month ago in playlist More videos from ndsuvirtualcell 9
nice!! thanks it helped :)
EvelynNLB 1 month ago
God bless the people who made this!! saved meeee big time. Textbooks, professors, wikipedia, none of it really helped. Except this amazing video.
shbni 1 month ago 2
@shbni I agree!!
joyblueeyes118 1 month ago
Wow, it was really helpfull!!! :)
Nanville10 1 month ago in playlist Favorite videos
The amino acids look like tic tacs ^_^
Thank you great tutorial, you've just saved me from wasting time trying to piece together info myself!
zeeiggy 1 month ago
i think ill actually pass my final tomorrow thanks!
rapedbyasquirrel 1 month ago
The large ribosomal subunit has 3 binding sites. You missed the E (exit) site.
belfastbomber189 1 month ago
I think I'm in love with this video...
Silivrin1 1 month ago
Thankyou, tis is a great video. But you forget about the E Site, which is the exit site. This only stated about the A and P site.
nissarachmidwiati 1 month ago
Who needs to read when you have You Tube...Just lovely ;-)
100Tatanisha 1 month ago
second year genetics class, teacher talks for 2 hours, video explains better than him in 3 minutes
abdoalsmoudi1 1 month ago
What a wonderful, easy to follow and to understand video. Thank you SO MUCH!!!
jesusclau1 1 month ago
This is not detailed enough!!
slumdogPREMED 1 month ago
@slumdogPREMED Where are the IFs, EFs and RFs and Ternary complex??
bishoprocknroll 1 month ago
This has been flagged as spam show
AP BIO book: 90 dollars, don't understand a word.
This video: Free, understood perfectly.
THANKYOU!
JaCey0928 2 months ago
THANK YOU SO MUCH~!
xFrostByte7 2 months ago
that is only a polypeptide not a protein? How is the protein form?
Tl82T 2 months ago
@Tl82T a polypeptide (from what i currently know) IS a protein, but depending on its length, and the amino acids in it, and their order, determines the proteins function. to simplify this: depending on how long the thing we see at the end of the video is, and the order of the colors (amino acids) depends on how it acts :D
imatrolly 2 months ago
That protein looks like a yummy chain of Mike N Ikes. Biology can make you hungry.
girlclasse 2 months ago
thats an awesome explanation...technical terms are used, however in a comprehensible speech, perfect for a advanced course student :)
prannyphuu 2 months ago
it amazes me that this simple animation makes more sense than my AP Bio textbook does
NonmetalAlkali 2 months ago 2
beautiful explanation, makes me wanna cry
5bubbah 2 months ago 32
Am I the only one who thought this was about language at the first glance?
WIFIM101 2 months ago
27 people failed their biology exam..
brentaamodt 2 months ago
@brentaamodt 28 people failed their finals
Darkichi7 2 months ago
the protein looks delicious :D
HHHNAMENLOSHHH 2 months ago
@irenelealortiz - yup' methionine is the start codon. It initiates, or starts, the process. (AUG)
coolgirl9567 2 months ago
I understood the concept. thank you for this video
2345sam1 2 months ago
is the first aminoacid always a methionine then??
irenelealortiz 2 months ago
i've watched this video for my highschool biology class and now my first year uni prof is showing this again.
PaliMatic 2 months ago 3
helped alot
as3dk 2 months ago
this is beautiful :')
akhilj36 2 months ago
fuck yea I love this shit
nholmes1372 2 months ago
The ribosome looks like that Mushroom character from Mario.
nforspeed91 2 months ago
Quick question. If the large ribosome subunit covers the tRNA and mRNA, how do the other tRNA molecules get in? Do they go through, or is there an opening?
pirateXhunterXzoro 3 months ago
@pirateXhunterXzoro they never really said inno but it wud want to seem dat it wud come in due to the corresponding of the triplet codes on the mRNA
lovestuck4444 2 months ago
@pirateXhunterXzoro They go into the A site by diffusion.
vladimirhorowitz 2 months ago
Thank you thank you thank you
pixelated111 3 months ago
helped A LOT!!!
Meltemfb48 3 months ago
This was very good demonstration!
lylyicing 3 months ago
Thanks for posting
Misslulelulu 3 months ago
thank yooou :D
carla22293 3 months ago
I did really helped
huixera 3 months ago
soo helpful, thank you!
kellobaas 3 months ago
Yea this def is the best translation video on youtube. The calm slow robotic sounding female voice really helped.
Tahontop88 3 months ago
Contact us for Professional Translation Services on: langjobs.com
MrAmi216 3 months ago
70 powerpoint slides explained in 3 minutes
flymaster 3 months ago
I hate this stupid class...
iluvyouwyatt 3 months ago
I'm from greece. my teacher told me to watch these video in order to understand better these procedures. :)
sofia0zoe 3 months ago
what will then happen to the trna whirly whirly thingy?
vincetheworldly537 3 months ago
liiikkkkeeeeeeeeeeee
wesiem1 4 months ago
Dude, im from germany and this video helped me more than my bio lessons ... :D
today many teachers are definitely too unqualified ...
TheOneOpportunity 4 months ago 50
@TheOneOpportunity same here! :D
ElenaNothingMore 1 month ago
@TheOneOpportunity YOU BET!!! LOL
100Tatanisha 1 month ago
@100Tatanisha OH, i like ur username "TheOneOpportunity". mad ting, which means cool in Jamaica.
100Tatanisha 1 month ago
@TheOneOpportunity Why do we care that your from Germany? haha
wtfspam 1 month ago
fucking saved my life. who needs a PHD biology teacher when this is better then mine?
ihat3youtubification 5 months ago
best translation video I've seen yet. Thankyou.
xoxMONIKAxox 5 months ago
i don't have a test or anything, i just happen to like biology
vladamac 5 months ago
This has been flagged as spam show
thanks :) it was helpful شكرا جزيلا لقد استفدت كثيرا
karph26 5 months ago
Help m3 grt... thnx
MyRonitSharma 5 months ago
thanks :)
Sawichaya27 6 months ago
very useful!!!! thank you!!! saved my life LITERALLY
tjk20 6 months ago
wonderful video! helping out my MCAT prep right now :)
drshankar 6 months ago
amazing video...thanx!
digitalraver81 6 months ago
this is shit
dereinederdichkillt 6 months ago
@dereinederdichkillt u meant this is the shit....
digitalraver81 6 months ago
This took like twenty minutes of explanation in the lecture. lol
americanboy717 6 months ago
@americanboy717 This is more like a week of molecular biochem, granted we went over every detail, but this 3 mins provided a better summary than my college prof.
cinsed 6 months ago
This is a great explanation of a process that is difficult to understand. Other videos are more snazzy but don't really explain what is going on.
marieceleste 6 months ago
This has been flagged as spam show
Now I got it^^
TheNeo1992 7 months ago
Great mini review for the MCAT. Thank You.
MrRahdiggy 7 months ago 3
Very detailed and not necesarry for what I need to know, but I like it! xD
XxXdragurlifeXxX 7 months ago
FUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCKFUCK
l0c0m0nster 7 months ago
thank you!I understood it way better than school...
josse432 8 months ago
I bet the views for these videos skyrockets around finals time
Skspier1024 8 months ago 116
and what is the poli A tail for?
macacalocaedoida 8 months ago
@macacalocaedoida
its for protection against ribonucleases and it stimulates translation
kiddowaiiyo 8 months ago
@macacalocaedoida : to stabilize mRNA and prevent the enzyme degradation of mRNA
wensisheng 7 months ago
Wow. I'm German and I understood it way better than the fucking German texts and pictures we had although I don't understood every word in the video :DD Thank you.
MissJackassMeintJenn 8 months ago
It's really good to understand the process :)
Alinuscitrusfaltus 8 months ago
quick question: when the ribosomal subunits are not involved in protein synthesis, do they stay together or drift apart? ooh, and are they held together by their own hydrogen bonding, the nucleotides' hydrogen bonding or something else?
SiberianHuskyF1 8 months ago
Comment removed
xinyez 8 months ago
@SiberianHuskyF1 If they are not involved in the Protein Synthesis they'll always be found apart from eachother, so yes, they drift apart after the polypeptide chain is completed. I hope this helps.
xinyez 8 months ago
Wow, what a great video!
So clear, thanks for uploading!
Gingerbreadaddict 8 months ago
The best way to understand the basis of translation see this.....i rate it 10 out of 10
asif121sofi 8 months ago
The best way to understand translation see this.....i rate it 10 out of 10
asif121sofi 8 months ago
sooooooooooooo nice
thanks
alturfy 8 months ago
I wish my DNA was a rainbow T_T
x3madcandyxD 8 months ago 2
Well, maybe not, since there are a lot of factors I need to know about... But this is good for the basics.
StormZephyr 8 months ago
You just saved me about two hours of reading my textbook.
StormZephyr 8 months ago
this is not totally correct, it doesn't show the E site after the P site, fundamental in the translation, but anyway it's a good aproach
Alucardbass 8 months ago
BEST rna protein synthesis found on youtube. THANK YOU.
OfficialAla 8 months ago
ohhhhhhhhhhhhhhhhhhhhhhhhhh...i didnt know there were so many tRNA's used in the process of eleongation. Now i understand the E site(elongaiton)...durrrr, lol
thx youtube
cradleofjohannes 8 months ago
AND THIS IS WHY I DONT BELIEVE IN EVOLUTION, MINITURE FACTORIES IN MY BODY.
RespectMyHate 8 months ago
This has been flagged as spam show
@RespectMyHate Whether you believe in it or not, evolution is a fact.
english2me 8 months ago
FINALLY! It all makes sense now! :D
thank you youtube for helping me study for my exam! :3
mlkin71 8 months ago
just.. how amazing nature is??
tudoralexe 8 months ago
I was so lost while my professor explained this. Now I totally get it. yay!
snm01 8 months ago
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i understand a lot better now :D what a nice video! thanks a lot
msmento92 8 months ago
i understand a lot better now :D what a nice video! thanks a lot
msmento92 8 months ago 2
warum gibt es zur trankription und translation so viele erklärungen auf englisch und nur so wenige auf deutsch :-O kann nicht mal einer welche auf deutsch machen bitte? am besten noch heute :-P
Kruemmeli 8 months ago
y does my professor make this seem sooo difficult -_-.... thank u youtube!!!!!
mreddiehardstyle 9 months ago 3
That is a very corlorful protein. Wish my book had the same color scheme.
sammy0chan 9 months ago
How can the ribosomes unit ''slides'' along the mRNA chain?
oasisoasis21 9 months ago
@oasisoasis21 magic .. no, jokes, actually it's cause it's pushed forward as the other tRNA leaves and the new one 'seeks shelter' under it to copy
katouatou 9 months ago
can someone please explain to me where the tRNA comes from?
FlyingGoomba321 9 months ago
@FlyingGoomba321 it is in the cytoplasm I don't know where it is created but it is just in the cytoplasm
TheSvenw007 9 months ago
@TheSvenw007
Actually, tRNA is transcribed from DNA in the nucleus in a similar fashion to mRNA. In eukaryotes, the major difference in production between the two is that mRNA is transcribed by RNA Polymerase II and tRNA by RNA Pol III.
In addition, for the tRNA to possess its corresponding amino acid necessary for translation to occur, it must first be 'charged' with the amino acid. This process is catalysed by the enzyme aminoacyl tRNA synthetase, which uses ATP to attach the amino acid.
TheSpecialSausage 9 months ago
@FlyingGoomba321 The tRNA is assembled by an enzyme known as aminoacyl-tRNA-synthetase and the resulting tRNA molecule is available in the cytosol where it will be needed for translation.
alittleunstable 9 months ago
i keep thinking the amino acids look like tic tacs during elongation
she8u2st 9 months ago
I finally get it now. cool beans.
blubberwalrus 9 months ago
did anybody else think "om nom nom" at 1:50? lol
big7bro7 9 months ago
wow. this makes so much more sense
emerica245 9 months ago
amazing!!
1992photographer 9 months ago
One of my favorite processes in cell biology :)
MTajvidi 9 months ago
bio ftw
orgasplosion 9 months ago 2
Comment removed
ltsTheMace 9 months ago
The first amino acid from tRNA is always Methionine (in eukaryotes)
Formyl-Methionine in bacterias (procaryotes)
ltsTheMace 9 months ago
Amazing!
ju5tys 9 months ago
Amazing! Thank you very much!
vseslav1 9 months ago
Thumps up if you think the narrator sounds hot.
plainlake 10 months ago
WOW!
Alhamdulillah finally I understood that.
SUPERB!
Thank u so much :)
smarty9oct 10 months ago
now im hungry for babies. i didnt know they were so colorful on the inside :P. thats me licking my lips.
grumpybritishguy 10 months ago
19 people still failed there test
ThaChinMen 10 months ago 5
A 1 hr lecture shortened to 3 and a half minutes. Outstanding! :D
DRS0LID 10 months ago 4
This is an awesomely perfect video and explanation.
greenranger8100 10 months ago
LIFESAVER VIDEO.THANKS A LOT
sangini11 10 months ago
thank you. these visuals helped heaps x]
forn012 10 months ago
OOOOOOOOOOOOOOHHHHHHHHH.
TGIFtomorrow 10 months ago
like if you're watching this because your bio teacher sucks!
xitsgianaxo 10 months ago 177
@xitsgianaxo No, I'm just a lazy student who has a final tomorrow and hasn't even read half of the subject.
BaseAndAcid 7 months ago 2
@xitsgianaxo not your teacher sucks, your government and your schoolsystem sucks!!!
Calvin8076 6 months ago
@xitsgianaxo hahaha I swear this made my day :D
luthehappy7 5 months ago
@xitsgianaxo lmfao!
SuperDuperSentinel 4 months ago
BARRRRRREEEEEEE CONFUSSSSSSSSEEEEEDDDDD
nvk1001 10 months ago
OMG I GET IT NOW!!!! :O
Link64 10 months ago 2
This is like two entire chapters in my book. I think I'm ready for my test.
nuhcolehan 10 months ago
I just looked it a few hours ago in our Biology lesson. And now I understand it- eventually!! :)) thx
godessshannon 10 months ago
this cleared up all my doubts.. awesome stuff!
SweetAsSugar27 10 months ago
I felt pretty neutral towards the rainbowness of the amino acids, but then that random yellow one near the end kinda irritated me.
lovecuocua 10 months ago
why is the music soo scary??
demiselena0fan 10 months ago
@demiselena0fan I don't know why - I find the whole thing a bit scary :D
godessshannon 10 months ago
life saver !!! millions of thanks :)))))
ithapaa 11 months ago
mpickotoooooo!!!
rafaaaaaaaaaa!!!
Rafasavi1 11 months ago
@Rafasavi1
prose3e sto ma8ima re
stefanakis94 11 months ago
An dn eixa Folla twra, siga mhn vlepate to view mou!!!
Jijifiongos 11 months ago
@Jijifiongos
re xameno partal prosese sto ma8ima
stefanakis94 11 months ago
@stefanakis94 sous siwph k swpene re!!!
Jijifiongos 11 months ago
Who needs $300 textbooks when you have this! I couldn't even understand my book, after staring at one sentence for 10 min I gave up. Best decision of the day. By far.
bassgoddess1618 11 months ago
oczywiscie kurwa po polsku nie ma ;/
dariagliwice93 11 months ago
oczywiscie kurwa po polsku nie ma ;/
dariagliwice93 11 months ago
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I HAVE JUSTUNDERSTOOD waht happens on A side, P side, E side, and how protein grows :D thank you so much :D
rockerrubyna 11 months ago
I HAVE JUSTUNDERSTOOD waht happens on A side, P side, E side, and how protein grows :D thank you so much :D
rockerrubyna 11 months ago
Teaches soooooo well.
samnostic 11 months ago
i have a question. where does the peptide go at the end?
tugo7 11 months ago
@tugo7 To rehab.
jk. :)
google it?
taylorkaitlyn 11 months ago
@tugo7 it leaves the cell to go where it is required by the organism. ps. by then it's called a polypeptide, or more accurately, a protein :) a polypeptide is a whole string of peptides that has taken on it's proper 3D shape so it can be functional (just wanted to let you know bc that distinction will come in handy on a MC exam)
hermchar231 11 months ago
@hermchar231 Thanks ahhah
tugo7 11 months ago
i do this for the lulz
xxTaKe2xx 11 months ago
This video did what my MCAT book couldn't.
aamantubillah 11 months ago
not the best translation video...
sfhsmello29 11 months ago
This video has one mistake that is apparent. In Eukaryotes, the small ribosomal subunit starts with an intact "charged" tRNA that forms the translation complex. This is different from prokaryotes, where the first tRNA joins the SRS after it has scanned to the start codon.
cuthwulf 11 months ago
Don't forget that GTP is required for the translocation of tRNA from the A to P before the next complementary tRNA can bind.
buriedinhw7 11 months ago
got midterms tomoro. this video was pretty helpful
persondude911 1 year ago
@persondude911 hahahaha me too lmao
polske322 1 year ago
thank you so much , now I can understand the whole thing
ed8widge 1 year ago
You missed creating of m