Kinesin Transport Protein

[prinzhuck]

Kinesin definitely walks like a boss!

[spoogegoat]

The Ministry of Silly Walks operates at administrative levels deeper than most people realise.

[themoray42]

Kinesin has swag

[18120polls]

Motor Proteins...haters gonna hate.

[Skrithuurz]

The deeper we look inside the cell, the more willing to learn how does this all work we should be, instead of making an educated guest that a superior wizard created it.

[themoray42]

Look at all the Captain Sciences trolling on the comments. $5 says they looked up this stuff a minute before posting. Enjoy the swag of Kinesin. DO IT AND ENJOY!

[CosmasNDamian]

That looks like a nano version of John Cleese as "Minister of Silly Walks"

[genkouhande]

haters gonna hate

[dabeshu]

@genkouhande

wut

[benthemiester]

This video should be called the neo Darwinian nightmare. The deeper we look into the cell, the more we see nano technological machinery, locks, keys, switches, regulatory systems, complex folding apparatuses, emergent and redundant self repairing systems, and thats just a tiny sliver of a tiny sliver. Encode opened up a new universe of information.

[justjessikah]

Omgosh that is so cute! LOL it's in us. #Imsoweird.

[Floatie114]

Professing themselves to be wise, they became fools.

[CatfishOneZillion]

@Floatie114 this is to do with transport of organelles in the cell

[maceyashort09]

i love anal!

[LooseYourHeart]

27 sec meines Lebens einfach verschwendet...

[eminov1]

To all evolutionists (worshippers of matter and coincidence)

BIG question:how is it possible that the kinesin know where to go?

Why you guys always use the words: creationists don't want to understand, don't want to see,they ignore evidence etc.etc. The logic that you guys use that nothing, but only coincidence, is scientific is a flawed one and is the shame and disgrace of the current century. Science is only a tool that shows god's creation/power. We come closer to god through science.

[jordanofthenorth]

Jesus tells kinesin were to go.

[0Lisiana]

Kinesin always walks to the +-pole of the microtubulus, dynein to the - end.

[tsferg]

Well, once you prove it or provide some evidence Ill believe it. If you can, you WILL go down as the most famous scientist of the day. Go.

[johndoe1990]

The fact that kinesin always moves to the axonic terminal happens because when it binds to the microtubule the conformational arrangement between the protein and the microfilament guides the heads on only one direction. If you consider that all the kinesins share traits among them, one of those traits is a structure in the heavy chains that when it interacts with the microfilament, only one direction for movement is possible

[BenjiNM2]

To all creationists we know why kinesin knows where to go. It is because microtubules (where these proteins walk upon) are polarized.

there is a protein (dyanin) which goes in opposite direction. To date, God and coincidence are still there to explain things that can't be explained yet. But in this universe there is no coincidence, only laws. Why are there laws or who made them is the only matter we should disagree on. (evolution = active proces, unbelievers are either uneducated or religious)

[bodmondude]

LLLLLLLLLLLLLLLLLLLLLLOL @ EMINOV1.

Seriously, for all those debating, dont even bother reading his arguments since it isn't even a proper debate.

Religion = accessible and used by anyone, and often misinterpreted.

Science = Only accessible by people who are knowledgeable.

Therefore proper discussion/arguments between the two should involve people who actually represent and understand their own religion.

[themirrorpool]

The earth is a disc, Galileo.

[alexvegas]

Why hasn't that method of transport evolved in animals yet? Lol. It's interesting how the two 'legs' have differently angles axes.

[bodmondude]

Well if it hasnt evolved in general, then it means it is not worth evolving, therefore our mechanism of walking is probably more efficient for current living.

[ReligionIsACrutch]

"Yes, we have a soul, but it's made of lots of tiny robots!"

[GodMechanism]

Result Directed Robots

[CammieSpectrum]

and By Result Directed, i mean, this process or it's constituents is not being explained primarilly by one rigid electric law

[2bornot2b1984]

@ReligionIsACrutch

Lol. You mean like our cells?

Tell me this. How do the proteins know what to do? Do they have a brain?

Secondly, WHAT MOTIVATES the proteins?

[ReligionIsACrutch]

@2bornot2b1984

The proteins are programmed to do what they do by our genes. Nothing motivates proteins. They are like a thermostat on the wall. They respond to certain conditions automatically.

[1Failboat1]

@2bornot2b1984

You're fucking retarded.

[2bornot2b1984]

@1Failboat1

"You're fucking retarded."

This coming from a sycophantic meme-douche who obediently regurgitates the prepubescent win/fail dichotomy peddled by mindless group-thinkers.

Failboat? Is that like a sailboat? What about fail-cars, or fail-planes, or fail-cycles?

You are projecting.

Look it up.

If I am "fucking retarded", then your parents are retards who fucked and spawned you.

Piss off, troglodyte.

[1Failboat1]

@2bornot2b1984

I AM SUPER INTELIGANT AND SMART U R DUM SHEEP

[Rao665]

@2bornot2b1984

You just blew my mind!....HOLY SHIT!!!. and look at the response...i think you blew his mind too.

[Skrithuurz]

@2bornot2b1984 The proteins don't need to know what they do. They do what they do because of their physical and chemical properties. Just like hot air ascends and cool air descends: that's because of their relatives densities and not because the hot air knows he must go higher and higher.

[2bornot2b1984]

@Skrithuurz

Hot air rising? That is kind of oversimplified. We are talking about little machines that unravel dna until they "know" they are at the correct position. match up bits of protein to form building block chains, then other little machines that know when to carry them over to another machine which then has the strings fed into it, and folds them into particular shapes depending on what is required.

That could be argued as intelligence, hot air rising can not.

[herpshnerp]

@2bornot2b1984 I somewhat agree with you, but the fact is that "knowing" is still the result of biochemical reactions that dictate the movement or confirmation changes in these proteins; they are following the laws of physics and chemistry just as hot air rises because of these same laws (just much simpler applications of them).

[slicerx08]

@2bornot2b1984 everything you just explained is due to chemical reactions/polar attractions/etc. they don't "know" what they are doing.

[Scofield0085]

@ReligionIsACrutch I mean...basically 125,000 steps that a motor protein-kines-in has to get through to successfully march along every millimeter of a self assembling-micro tubule. That's equivalent to THE THICKNESS OF A DIME. It's simply amazing!!! And all through natural processes powered by ADP. Evolution is just so staggering & beautiful, don't know y why ppl have to give any credence to a creator....Indeed, yes we have a soul!

[Empeinmortal]

cute! haha

[eggbertsmith]

yo dawg, I likes how dat nukka rolls, yup yup.

[rollininoldstyle]

i could not stop laughing after i read this =D

[olympicrodriguez]

How did this evolve??? Freakin amazing!!

[cwhalsewang]

more cool in "inner life of a cell"search this.

[tobyw87]

Ya but you can't see the protein subunits!!!!!

[redelmahdi]

WTF... the protein sub-units on a biological molecule of THAT size... ?!

[cwhalsewang]

more cool in "inner life of a cell"search this.

[colomadri55]

im in a high school bio course

i saw a video about kinesin

its so cool

[tobyw87]

I am not exactly sure what you are asking but the kinase protein transport is certainly systematic. The animation makes it look a bit asymmetrical but if you look at it from the top it looks much better. Kinase transport proteins carry out many different functions throughout the cell. One of which carrying the new proteins from the smooth ER to the golgi appartus.

[murderousrage]

Is this the 'symmetric inchworm' mechanism? It looks asymmetric to me, with one heavy chain always hand-over-hand and the other always inchworming. If they are homodimers how could they possibly function by different mechanisms?

[OghamTheBold]

Looks like 1 behind could trap the 1 in front

Draw 2 and shoot at 45 deg.

[TurdFerguson98]

Why that robut got such big feets?

[drwierd]

good question