How Does Cocaine Affect The Brain? - How Drugs Work, Cocaine, Preview - BBC Three

[bfreezeik101]

and ill bill !!!!!!!!!!!!!!!!!!!!!!

[bfreezeik101]

la coka nostra LNC thats coke ! everlast dannyboy dj lethal slaine rock the fucking house!

[lockdnloaded17]

Just did a few lines before watching this.. id have to say the information is corrrrreect

[DontClickMyUsername]

weed is all i do fuck cocaine

[DenaliMt]

@Sarabower1 nope

[mariogamersidequest]

Full Documentary

t3fMoI0qMSA

[amsalwajih]

Thanks BBC, all you've done is dramatically increased my desire to do cocaine

[sarabower1]

@amsalwajih then you must be one dumb fuck

[ferrthepeace]

Fuuuuuuuck.

[Davincciable]

The CIA Inception 

[MrGuzman101]

I wish drugs didn't have side effects the world would be so different...

[TheTy92ty]

I wish there a drug that made to make our dopmine last for hours. Not a side effect but a true treatment to whatever.

[thesixthfamily]

Tha same system becomes activated wen sum1 falls in love !

[JoliQuZ1]

@thesixthfamily No that's seratonin

[EzThePker]

@JoliQuZ1 Oxytocin. Certain serotonin receptors when activated will stimulate oxytocin to be created so you're partially correct.

[keir193]

i rarely do it but i have been doing 500 bucks worht all night and tis a good time. only now and then.

[mikeyyyyb1]

do some coke n fuck put  that dopamine intoo overdrive

[mikeyyyyb1]

my jaw clenches when i rip a fat railerrr why?



[longbeachk1d]

@mikeyyyyb1 that hapens to me also who knows why tho

[ALWAYSHATEDON100]

That's Y that shit feels sooo good lmao, :-x sorry but it does

[mikeyfig23]

some crazy shit!!

[MrSandNaggar]

why are you promoting cocaine , this is fucked up , u kno wat it has done 2 people u dnt wanna know themisery after

[almostskater3210]

@MrSandNaggar

This is promoting facts, and it doesn't have to include a fucking lecture on why not to use it. In the end, it is only going to hurt you, but cocaine feels good, end of story.

[ByTheShortAndCurlies]

Nothing worse than listening to cocked up people that think they are the center of the universe.

[Awshbuscus]

Thing is, though, that after the receptors are used in such a way, they have trouble going back. It leaves damage in a sense that your brain doesn't produce as many of these chemicals as it used to, much like meth, but in a much lower extremity. Eventually, the brain will need cocaine to feel pleasure at all, at which point you have reached addiction. Coke is an addictive drug, so be careful with it.

[Kesam100]

@Awshbuscus be careful with it you say.. but is it worth trying, you know, like.. just once?

[Awshbuscus]

@Kesam100 Well, once, or a few times, maybe once every few months or so max, so it's completely out of your system before you try it again =/ Just be real careful with it. Don't start doing coke every weekend or something, that's too much, though it might not seem like it, until you try cutting down and have trouble with it. But yes, to try and every once in a while, I see no problem with, as long as you don't get caught ;)

[thesithxv]

This encourages cocaine use.....

[Cainkane1]

I have an ex friend that used this shit. I ended up hating his guts and so did everyone else around him.

[conman2317]

Reading through the comments is like a realization of how utterly stupid human beings are.

[edwinm1]

@NovemberZuluCharlie i prefer the hallucinogens over those two myself...they really open up the mind...and give you a muthafucking trip...nothing like a good shroom dmt or lsd trip!!

[LegendaryDancerMarc]

ironic cus i just saw this in health class today =p

[Cognitionz]

Fuck cocaine, I would rather go get some upper prescribed.... Hell even some wieght loss drugs like phentermine are similar to amphetamines.

[xXRiTaLiNx]

same as Methylphenidate ( ritalin ) , except Methylphenidate (ritalin) also increases norepinephrine,

and yes a high amount dosage of ritalin can be the equifuilt to cocaine ;)

stimlaunts 4 life ;3

[SeMoTeMo21]

thnQ BBC it was really usefull i studied on it 4 time, but i didn't understand till i saw ur video it was really usefull ,,,,,,,, keep uploadin'

[itssimpleiwinyoulose]

Thanks, the kids love it

[SmokinHERBking]

@itssimpleiwinyoulose what the fuck are you talking about?...hmm?

are you my doctor? !! come on spit it out, why am i typing so damn slow..i dont know why what to say. iiiiiiiiiiiiiiiiiiiiiiiiiiiiii­iiiiiiiiiiiiiiiiiiiiiiiiiiiiii­iiiiiiiiiiiiiiiiiiiiiiiiiiiiii­iiiiiiiiO MY GOD!!!

[TASSOS502]

I got 82% on my Canadian politics essay and I thought of my arguments high on coke. Using it responsibly and not doing too much can actually have surprising effects. If you use it irresponsibly, then you're going to be stinged out at 5 in the morning looking for more....

[YouMakeMeBelieve]

meth does the same thing

[LFCLEWIS4]

@octopus0051 you idiot don't do it it will fuck u up

[cesa180]

@LFCLEWIS4 first of all 7 times in three years isn't even that much. absolutely nothing to be concerned about. secondly dont judge u tosser

[LFCLEWIS4]

@cesa180 why do u want to even try it its stupid i have gone without trying it or any others so whoever does it ur just a bunch of idiots especcially you

[cesa180]

@LFCLEWIS4 you have no business judging people like that. if you don't approve of it, just stfu. no one cares what some random douchebag on the internet thinks.

[Octopus0051]

I am 24 and I took cocaine 7 times since 3 years !

I love it, so great feelings !

My advice: take it when you are in vacation and in unstressful moments !

[masticatingmyself]

orgasms, sleeping, eating, and getting shit done releases dopamine naturally. that's why coke is so addictive. you don't feel like doing anything else. just lost my job.

[lexx364]

Mmmmmmmmmmmmmmm good!

[ryanjohnsond]

Man, how does one go about animating something like that? The brain neurons are great!

[kingmanted]

Don't tell us that it eats a whole in your brain or anything...noooo.

[Horicert]

Cocaine is a selfish, ego driven drug.

[kazz1212]

Tried cocaine more than 30 times and now stopped and dont even want it, but the thing it does mess up your brain, dont matter who you are, it will mess your brain up and for some people it can be damage for life, """"BIG TIP & SUGGESTION DO NOT FUCK WITH IT''''' its one of the worst thing you can do to yourself.

[Nitharsan2008]

so dope is derived from dopamine?

[Whitewine12]

"I feel so dope"

[MultiNerve]

Pretty much, drugs are neurotransmitters that do different things. Cocaine causes the brain to release more dopamine (a natural neurotransmitter) and sends more to the next nerve cell.

[wokstar34]

i want to try this, who knows a guy ;D

[dvzqz87]

you get the same exact feeling from caffeine, which is why im a caffeine addict

[cesa180]

@dvzqz87 i highly doubt it gives u the exact same feeling. that's ridiculous. by that logic anyone that drinks coffee in the morning spends the next few hours completely high.

[dvzqz87]

@cesa180 well they do lol, caffeine is a drug and it gets you high and it has a half life of 6-hours so you do feel it for a few hours, it doesn't give you the same exact feeling cocaine, but it 's similar in alot of respects, cocaine and adderal have much cleaner more intense highs, but caffeine still increases the synapse activity between the neurons, activitates the pituitary gland which causes an adrenaline rush, and increases levels of dopamine, all these are symptoms of cocaine consumption

[dvzqz87]

@cesa180 annnnd you probably wouldn't know that becuase you've never tried cocain or adderal

[Cinek240493]

The problem is, that some morons think, that drugs are dangerous without having any knowledge about it. I`ve never heard, that Marijuana or DMT killed someone, but I`ve heard, that alcohol kill lot of people. In my stupid country - Poland - about 800 000 people are addicted to this shit (we have 32 milions of citizen) and that`s a problem. Lot of people think and say, that natural Cocaine do not make you addicted (like for example Freud).

[nicknackisback]

@Cinek240493 Good Point!!! Can't agree more :D Stupid Noobs

[senseipuffz]

honestly, (i live in south florida so the coke is always atleast half decent) its not worth the money... i would feel 100X better if i drank abunch of coffee and then do some oxycodone instead of doing coke

[Xzariah]

BBC almost makes it sound like doing cocaine is very good for you, they shouldn't put this stuff up without the continuation of the long-term effects otherwise since its BBC and all, with its awesome status and everything, there are people who are young and dumb enough to believe it's all just good and don't realize what it means to have your dopimine receptors disappering, and how dull everything becomes when no longer high + needing more nd more of the drug each time.

[Pu55yEa7er]

@Xzariah Actually the receptors don't disappear. Instead they retract permanently due to the hyper stimulation of the drug. It's called down regulation.

[cesa180]

@Xzariah this is just a segment from a full one hour episode. they cover all the short and long term side effects of the drug and in no way encourage it, simply inform. they are not suggesting that it's good for u, they are just saying what it does to your brain that gives it the effect.

[quidproquo2004]

I need sex -- to survive!

[LifEjEE1H]

my day began with a bottle whisky and some good lines of cocaine and it end's with a good weed so i can sleep :)

[ZzX42]

that doesn't help your case much

[23razerblazer]

uhhh.. so its not bad for the brain?

[SOF006]

@23razerblazer no but its bad for your health. Its addictive, having to much can kill you. Don't touch any form of drug unless its deemed safe to use by a qualified doctor.

[s90e]

@SOF006 Except cannabis. No harmful side effects.

[J41mEV4rG45]

@23razerblazer according to the documentry, no

[texmexspm]

@23razerblazer Well, this flood of dopamine eventually causes your body to react by producing less and less making you more dependent on the drug to feel any kind pleasure in life. Maybe if you use it once a month it would not lead up to that point but this is only a personal opinion.

[almostskater3210]

@texmexspm

Cocaine doesn't cause less dopamine to be released after extended use because it doesn't release dopamine. It just blocks its respective transporter, but it does lead to dopamine receptor downregulation.

[Mikerulez101]

I love how they put "have sex" in the list of things essential to survival

[T9erful]

@Mikerulez101 lol how you think we got here

[TheKokanin]

@Mikerulez101 So you mean sex has nothing to do with human survival?

[TheArthurbr]

@Mikerulez101 it is

[AlexEttelis]

@Mikerulez101 That's "list of things essential to survival" according to the brain.

[MorningInGermany]

@Mikerulez101 It is essential to survival, because if no one felt like having sex the human race would die off.

[sugangamer]

@Mikerulez101 Its a release of the best working dopamine. Naturally, we get dopamine by these three things, but the most powerfull is sex.

[oaknairb]

@Mikerulez101 what that really means is that sex is essential to the survival of our species

[bajatmerc]

@oaknairb duh

[rustypolymath]

@Mikerulez101 Well, obviously this was dictated before the invention of cloning. :)

[fdota]

@Mikerulez101 survival of the species =]

[Mrmtjones]

@Mikerulez101 well...it is essential. how do you think you got here

[WAFCWALKER93]

@Mikerulez101 it is lol

[rdyjur]

@Mikerulez101

no shit sherlock

[tke992]

@Mikerulez101 sex is essential to survival if you went to college you would know sex is one of the things on Maslow's Hierarchy of needs

[johmedis]

@Mikerulez101 Passing on your genetics is essential to the survival of your species...

[crusher1427]

@Mikerulez101 it is essential in context

[sasuke4612]

@Mikerulez101 it is....its called birth

[lukekotleski]

@Mikerulez101 we do need to reproduce?

[ManGaStyle1993]

@Mikerulez101 This comment shows how stupid most humans are

It talks about survival of the human kind not about your personal survival

omg

[Ven0mB0Y]

@Mikerulez101 I instantly recognized your username! EPXW!! so funny.

[Mikerulez101]

@Ven0mB0Y haha, thanks man.

[StrangeCognitivism]

If this were an American production, it would be laced with biased mentioning all its terrible, long-term detrimental effects, as opposed to just giving the facts of what it does and how it works. Go BBC for being unbiased and scientific!

[ernesdee2o916]

Coke is not to bad just make you numb not too appt up like crytal meth. 

[s90e]

@ernesdee2o916 Umm ok. It kills the dopamine receptors. Killing parts of your brain can't be good for you.

Every just stick to weed!

[The137313]

@mcnultyfrank here's my conclusion, cocaine, LSD, and MDMA all have depression symptoms after previous use. Now in order to get rid of the shitty depression, you have your organic anti depressants, marijuana, shrooms, and salvia. They'll help you out with your shitty crash.

[The137313]

To be honest, coke isn't that bad, there is an alternative organic version of coke, chew on the coca leaves, you get the same effect, now powder version of coke, all you have to worry about is addiction, which you can get addicted to everything masturbation, sex, etc. Addiction is addiction no matter what it is. Now back to powder coke, you deal with addiction, withdrawal, and some nasal problems. Look point is you won't suck dick for coke, only for heroin, crack, and meth. Trust me research.

[astralslide12]

I DONT LIKE COKE I LIKE WEEDS !!

[TASSOS502]

its true, when i used to do coke my brain would have 3,000 things travelling in a minute, yet i would just sit there not even able to speak or comprehend anything and let my heart beat fast and watch my weight thin out and my dick struggle getting an erection. its fucked if u wanna do coke dont abuse it. its fun when ur at a party and havin fun but if ur stingin out at 6am not sleepin with the stock market channel on and lines busted, then u got a problem friends

[cradleoflinkinpark]

hey no wonder i was naked in the police station,, snort o_o

[lexx364]

@cradleoflinkinpark you too? damn lol

[MiSSannaira]

omfg, go ahead try cocaine. you will feel great at the moment and then BOOM you're addicted on the side of the street begging for money.

[Cyworldabcd]

wait so was this supposed to convice me to take cocaine? :D

[EoghanDog]

@conman2317 wtf you really are a retard wat course you do in uni lmao

[Revolution2pointO]

cocaine is good. especially all of you out there who have trouble meeting guys or girls. if you do cocaine odds are you going to be banging someone tonight.

[mkf0528]

Thanks BBC. Now I want to do coke.

[ThElitE]

@mkf0528 LMAO...I know, right?

[baleydee]

@mkf0528 seriously XD

[roddersis1]

not being funny but i fort cocaine was bad for you by watching this it make you want it ;)

[BoomBoom5678]

This is going to help SOO much with my final bio project

[tomvercruysse]

@BoomBoom5678 SAMEEEEE!

[purplegorillaamateur]

This video just garanteed me a passing grade for my Biology One World Essay !!!!!

[themorganator4]

cocaine sucks..i get higher of a cup of coffee

[trejuk9]

@themorganator4 are u fucking insane?

[themorganator4]

@trejuk9 nope, cocaine barely affects me and i have done lines from different sources and i have done about 4 lines at a time on average, and i still get higher off coffee, maybe i have a very high tolerance?

[iiirrroonnnn]

@themorganator4 maybe some1 has been selling ibuprofen

[Shotcalm]

if i tried cocaine once(one snort) would it do damage?

[mcnultyfrank]

@Shotcalm It could, but if done in consideration it is fine. What this video didn't say was that when the effects wear off you are completely drained of dopamine, which is the reason for a comedown which will leave you feeling depressed and a bit drained. And do you know what the cure for a comedown is? More cocaine! You see where i'm going? You're gunna need more and more lines of coke to stop this comedown which will inevitably come but will now be more of a crash. MDMA is the best drug!

[sudreme54]

@Shotcalm

and im pretty sure if its your first time and you only do a couple lines youll be fine just dont do it too often you kno?

[amirleo100]

@Shotcalm my friend just O.Ded and died on coc... im just sayin...

[LuisCeja1000]

Cocaine is a hell of a drug

[patriceyo1]

yea but cocaine is positive once in a while

it is very easy to not get addicted

take me for exemple, i always have a bag of cocaine in my house but i m just doing it one or two time in a month.

It is simple, dont take drug to feel better, take drug to be happier when you are already happy

ps. sry for my bad english, i m french

[Theronnnnnnnnn]

@patriceyo1 Euh, Pat. C,est vraiment pas une bonne idée d'en prendre tout simplement. L'expérience personelle est la pire à prendre, pour défendre un point. Même à ta fréquence qui est quand même moins haute que la plupart des usagers de la cocaïne, 1 à 2 fois par mois, c'est quand même pas mal. Le fait que t'ai un sac en permanence chez vous montre aussi que ce que t'affirme est un peu... faux. Ca veux dire que t'en achète une certaine quantité avec régularité. C'est une addiction "long term".

[almostskater3210]

@EddygPS3

You act like it's impossible to not become addicted

[o0gabo0ga]

@EddygPS3 im sorry but 50% success rate, i.e you do or you don't? lmao...thats 50-50 yes or no... bad percentage you pulled out of your ass there.

[killersdww]

Best shit ever and about your brain not producing dopamine again that is so much bull shit the only drug that stops your dopamine production for good is pure crack....and btw the only 2 non Sintetisis drugs are weed and cocaine so they are pure natural drugs. Its not like if you snort a line of cocaine you will never be happy again so you go addicted becouse you need to feel happy thats bull shit. But yea this shit is expensiv

[almostskater3210]

@killersdww

what about opium? or dartura? or salvia? or fly agaric? or blue lotus? or magic mushrooms? or peyote? or kratom? the list goes on....

Natural doesn't mean shit. You'll never see me do datura

[mere0006]

so cocain just damage dopamine system , and the neurone dont get damaged after one take of cocain ... you intelligence rest the same?

[killersdww]

@mere0006 no it actually doesn't ...that is why a lot of the best business man use it on a regular basis. It gives you a lot of self assurance. Well ofc long term uses are bad but for example weed kills a lot more neurons then cocaine.

[mere0006]

@killersdww `what is ofc ? it is cocain ? , and cocain are chemical weed 20% chemical resst is natural ... but if i smoked everyday 3 hit of weed during 3 month ? do i lost everything ? do i will get my brain normal ? i worry about this this time... need some information ..

[killersdww]

@mere0006 m8 how can i explain this to ya all drugs are bad and long term use is bad ofc...cocaine fucks up your cardio-vascular system because just like ecstasy your heart will beat a lot more faster then usual same goes for your dopamine production because your brain produces so much dopamine when under the effect your organism fights back by reducing your dopamine production so you know Wat i mean.....but it is not like weed when you smoke for a long period and start forgetting shit

[mere0006]

@killersdww okay i understand weed about killin neurone so memory loss , chemical it more about cardio vascular and dopamine(goodfell) system when effect gone life will seem sucks..when you said long period it is like 1-2 years smoke everyday 1gram?( and i talk about weed of street dealer).. and do you know if one persone stop all drug for longtime neurone and all body organism regenerating back to normal

AND THANK YOU SO MUCH.

[killersdww]

@mere0006 That is the big problem neurons are the only cells in the human body that don't regenerate ever...that's why we have so much brain mass that we actually don't use...so your body wont regenerate neurons ever if you fuck up your memory then it will stay fucked for the rest of your life....as for cocaine you will be in a general depression after you quit because your dopamine production is shut down and usually a lot of cocaine users develop heart diseases. So not much recovering done

[WitchyFeatherDreams]

this makes cocaine sound like its not a bad thing

[ItsMTTTTT]

cocaine's a hell-of-a-drug

[bondservant4Him]

everybody knows the negative aspects of cocaine finally a video that teaches us why people do it in the first place

[baznian]

Drugs are like cheating life lol

[caroegc]

Oh my God. This video is essentially promoting cocaine? Shit. Why didn't they mention the lows after? They're just saying how it makes you feel really good. NEVER take it there are serious after effects. It makes some people go truly insane in their trip.

[XPrettyXSceneXGirl]

@caroegc (As a previous cocaine user) I wouldn't say SERIOUS after effects. You just want more,but that's pretty much the same with any other drug. And idk about you,but me or any of the people I have been around that did coke never went "insane"...everyone acts pretty normal,like nobody dances all crazy or says stupid crap. And this is only part of the show,they have that other preview about the "cocaine burnt a hole through my nose" ..so they're not promoting it at all..no sane person would.

[203grad]

that shit fucks with your head and i know first hand how it affects someone my bf has gone insane he thinks people are watching him and are after him and thats days after he has used it so don't say IT DOES NOT CAUSE YOU TO GO INSANE BECAUSE IT DOES!!!!!

[203grad]

that shit fucks with your head and i know first hand how it affects someone my bf has gone insane he thinks people are watching him and are after him and thats days after he has used it so don't say IT DOES NOT CAUSE YOU TO GO INSANE BECAUSE IT DOES!!!!!

[XPrettyXSceneXGirl]

@203grad Uh,I can say what I want to because I've had experience with it as well and I'm sharing MY experience with it. I wasn't stating the long term effects,I was saying when you're on it people don't act "insane" like they do when they're on other drugs or even alcohol.

[TheNicholas0202]

Tony Montana!

[ChidoriAnbu]

nothing wrong with doing a bit here and there

[nukeusa911x2]

@ChidoriAnbu agreed. I dont like coce though, the effect is alright but na, i just dont like it, its not for me i rather pop some x.

[crazygame7]

@Th3NorseDrow no, it does not block receptor sites, the receiving neuron rids itself so the cell will not be damaged (or become way over stimulated with dopamine).

[whatrugonnadocrazy]

never get addicted to cocaine, the after effect is like the devil just stole your soul and your completely empty inside with no purpose.

[Fatboylt2]

it forgot to say in thre mornign u feel lower then a bow legged catapiller ha

[nasgulmage2]

i hope this isnt trying to put people off.. because its making me want some!

[tweezybabeh]

If you wanna get down, down on the ground, cocaine...

[rckon777]

Dope....amine

[TB0NENiNJA]

@KhashSter1R4N top stuff my man, get your hustle on

[MrPaulAlcantara]

science is fun 

[TheGoGoCommandos]

numbskulls...it does nothing but gets you numb! For real psychotropic effects try amphetamine sulphate, mdma, lsd, or hash. This is cartel propaganda. Seriously there's a lot of it those film cans in the bbc's trailers!

[TheGoGoCommandos]

@KhashSter1R4N You are a frickin' nob to say that!

[seeriktus]

Antidrugs propaganda

[Mookburger]

How does cocaine AFFECT the brain**

Effect = Noun

Affect = Verb

[Gimacol]

@Mookburger Probably the accent his has ;)