Added: 4 years ago
From: msc0328
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  • :O wooooaaaa

  • Comment removed

  • RNA polymerase: " fuck yeah"

  • I think the wiggly thing is the initiation factor, which brings together the mRNA, tRNA, and the small and large ribosomal subunits.

  • Having my midterm exam tomorrow. -__- youtube save mee. D;

  • We had to watch this in Bio today. .__. Am I the only one who finds that wiggly thing creepy? And is considered that I don't know what that wiggly thing is?

  • grrrrr...

    how do i have a C in biology?!?!

    Youtube better make me smart...

  • Have a test on proteins synthesis tomorrow....

  • @tteu123 I'm in ib hl right now and I see where you're coming from. So much goddamn material and I'm stuck with a teacher who has barely taught us a single biological process. I have my midterm tomorrow. CRAM TIME.

  • Mr. Fales! Period 2

  • @GOObaju O: DO YOU GO TO BC TOO!? I have Stuart. Final tomorrow.

  • wahh my exam is tomorrow. & i have to take it on a computer. Someone help me with the codes? I think yes!

  • the best thing in this video is that everything is on real time!!!! cool!!! this is happening right now inside you body!!

  • Anyone do IB HL Biology? I do and my mock exams are next week. I'm completely and utterly fucked.

  • Fuckkkkkkk Ap Bio

    

  • DNA --transcription--> RNA --translation--> Protein

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  • yeah Ms.Kane period 3 !

  • if teachers would show this video i would understand directly...

  • How do these substances transferred to the right location they are in need without having eyes , legs nor intelligence?

  • @Transfusions Everything is highly concentrated in the cell, which is a very very tiny place, and all moves very fast, (this is called brownian motion). Eventually the "right substances" get the the "right location"

  • @N0M4D88 Interesting. so it's more of probability theory by brownian motion than intermolecular force or something like that? I shouldn't have skipped biology class when I was in high school.

  • @Transfusions Not sure i got what you mean by that. Brownian motion is the force that will bring the tRNAs to the ribosome, but when the right tRNA "plugs" in the right codon of the mRNA in the ribosome, intermolecular forces intervene (small changes of conformation (shape) of the ribosome, which stabilizes it). Energy is released from this compatible interaction and it allows the aminoacid to link with the peptide in formation, the tRNA to be released and the ribosome to move up one codon.

  • Anyone from ms. sayers bio class watching this for the test tomorrow lol

    ??

  • that was sweeet. 

  • Anyone watching this video from Ms. Anderson's Pre-Ap Biology? Haha if you see this comment Noah from 6th hour says hi.

  • @Noahconstricto Zulema from 1st hour says hi to you Noah!!!

  • I dont get this part, each transfer molecule has a unique three letter code, there are 20 amino acids each with its own three letter code. which is fine, Now the ribosome matches the three letter code on the RNA with the correct transfer molecule and hence amino acid to build the protein, which is fine, but who brings them in order? what if the correct transfer molecule doesnt come along? Will the machine(ribosome) just wait? Its just a dumb chemical, how does it have intelligence like that?

  • @ashwinbhat123 The transfer molecules, called tRNAs, don't really get "brought in order". They basically float around and get to the ribosome thanks to brownian movements (everything moves really fast at the molecular level) so eventually the right tRNA will find its match. If it doesn't "fit" the codon (The three letter nucleotide code in the mRNA) the link won't be stable and it'll be replaced by the right tRNA eventually. Look it up in wikipedia, it's rather trustworthy for scientific topics.

  • @ashwinbhat123 I'm sure the chemical reaction doesn't occur and it just floats on by.

  • the music terrified me

  • Aren't they supposed to have poly-A told and 5' caps on them before they leave the nucleus?

  • after the video was over i accidently clicked on the big right video...noo nooo BIG MISTAKE

  • My biology final is in 3 hours. I lay my fate in your hands, youtube.

  • at 1:44 she says nucleic acid U. Uracil is not a nucleic acid.

  • Watch this when your'e high ahahahaha.

  • @superomar13 I just did. Woah. 

  • @superomar13 i am lol!

  • Looks like something that someone would try to tickle you with to me.

  • boobs

  • thats fucked up

  • I had to watch this video three times before I finally understood what was being taught. I haven't had biology since high school and even then I didn't understand. I'm one of the stupid ones! Thanks for posting!

  • what is the name of the blue protein that transcribes? the one that is making the ARNm

  • @WeBackToRun I believe it's RNA polymerase

  • @alanahilliard2010 Thanks man

  • Hey Ms. Fortes :D

  • this is actually pretty cool

  • Yup test tomorrow... Screw my life. :(

  • this video is NOT specific at all.

  • how many people here have an exam tommorow..

  • @jliro1 i have one today B\

  • @jliro1 I do!

  • @jliro1 8:30 tomorrow :)

  • This is pretty good. It's succinct, yet has all the crucial bits in it. Really useful for Bio noobs like me.

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  • Ok, wait, but in fruit fly dna we see bulges where active transcription is going on, this model doesn't allow for bulging...how does that work?

  • this video is pretty trippy

  • Is the blue molecule helicase?

  • This is the most crazy compli-fuckin-cated thing ever! If your mind did not have a mini stroke when you watched this you better open your eyes wider and rewind. If you proposed this idea before modern science had studied it you would have been burned at the stake immediately. How does this transcription mechanism not have some sort of conscious entity driving it like a tractor? We live in the craziest place and we all just sit around and reject the enormity and profound mystery. Let's wake UP!!

  • @jsummonsm1 The "conscious entity" does not exist on this level of nature. It's a mixture of the properties of atoms (electonegativity etc.) and distribution / concentration of them.

  • @Zimminimal You say this as if you KNOW. I studied for many years in chemistry and molecular biology probably like you and in no way can you sum up these series of movements by some quantum mechanical dogma that was vomited out by your professor. Do you seriously think we have any grasp of this shit? Our text books say "this is how it works" but what they really mean to say is "we have spent a fuckton of time and money studying this, but our little monkey brains can't quite get there yet"

  • Hello ACP bio lab students!!!!!!!111111one

  • @Qoutehappy OHAI.

  • Cytosin, Guanin, Adenin Uracil // Thymin

  • This animation has been a great help!

  • Thanks for this video! Made me understanding those processes better.

  • what is the blue molecule called?

  • @punk1250 RNA polymerase.

  • @punk1250 RNA polymerase much like DNA polymerase (only serves way more functions)

  • this is some freaky shit.

    the animation.

    looks like pipe cleaners but it's also spooky

  • xin chào mọi người

  • @huynhminhhung92 is that Vietnamese? my mom translated to english for me :)

    she said it means hello, kind of a greeting in vietnamese

  • thumbs up if you thought you saw butterflies at 2:30

  • No, U us called uracil. It replaces T thymine on the mRNA strand.

  • wooooooooooooooooooooooooooooo­oooow...

    that was just mind-blowing.

  • this is yantram bpo pvt ltd providing video transcription & much more like Our experts of audio transcribers & Video Transcription Services will undertake Transcription of a variety of dictation across a wide range of disciplines including notes, Audio Typing Service,Podcast Transcription,Online Audio Transcription, Online Video Transcription, transcribing correspondence, business reports, contracts, minutes, personnel appraisals, legal documents, and surveys.

  • So in real life its not like the transfer molecules "know" that its their turn to go into the ribosome (which is what it seems like in the video), but the process of translation won´t continue until the right transfer molecule gets inside to match the code? I´m wondering if my guess is correct...

  • @HunterLovell Yes, it is exactly as you say. The tRNAs (transfer molecules) goes into ribosome randomly, and the process goes on when the right tRNA is found (the right one means that it match the mRNA template [the yellow chain]).

  • The ribosome is belt fed! hahaha!

  • thank youuuuuuuuuuuuu

  • the sound affects and realistic quality of this video make it pretty epic. i'd sit and watch this all day rather than sit through a 2 hour lecture and 3 hour lab.

  • all i can say is wow ;) best stuff i've seen in years!!!!!!!

  • eww the stuff that was moving in the first 20 seconds looks like a monster growing and about to attack me! what was that?

  • Thank you for this clip! I adore how realistic this is compared to the other videos. :]

  • and of course hereditary nano tech required no intelligence behind its obvious design. This video is christian propaganda!

  • Trippy.

  • So amazing. I feel so lucky to be living in an age of technology and information. That we can know so much about our world and ourselves. I wish more funding would go into the sciences, instead we waste time fighting in wars and giving millionaires more money to buy more yachts. Every student in college wants to go into advertising or something as equally meaningless. I love science and I wish I could comprehend and grasp all of the sciences. I'm trying my best to learn more every day.

  • the tRNA looked pretty fuckin gross

  • Hey, guys.

    I have a biology final tomorrow, and for my essay question i have to explain how you make protein from DNA - but it focuses very heavily on translation and transcription.

    I still don't entirely understand it, so if someone could please please explain the whole process to me in layman's terms that would be sooo much appreciated!

    (Before tomorrow morning would be ideal.)

  • Such a cracking video I class it as a form of revision for my A2 bio exam next week- who said revision wasn't fun?!... definitely should be more videos like this.

  • WOW!! what a great video!!

  • 1) Why doesn't this talk about introns and exons? ):

    2) Where does that one amino acid attached on the tRNA come from? What I mean is, does a tRNA exist with an amino acid naturally, even before translation process, or is the amino acid made during the translation process?

    3) If the tRNA exists beforehand with an amino acid, how is that amino acid created?

    Please answer my exams are next week and this is a bit unclear to me.

  • @XxXdragurlifeXxX

    1) This video avoids talking about introns and exons for simplicity. Best to consult a book for clarification on that.

    2) The amino acid is added to the tRNA before trannslation begins - there's a whole process where each tRNA gets its own cognate amino acid added to it.

    3) Amino acids are basic building blocks that usually already exist ... proteins are broken down into amino acids and these are re-used by being attached to tRNAs and getting added to new proteins.

  • @msc0328 Thanks for the fast reply! I understand it now (:

  • @msc0328 also this gene that may have been copied may have been from an bacteria so talking about introns and extrons would not have been necessary.

  • @msc0328 At 1:38 the video says that "The letter 'T' is replaced with a closely related nucleic acid known as 'U'." Shouldn't it be a nitrogenous base?

  • @msc0328 This video avoids talking about a lot of things. I don't think it would complicate matters to mention what exactly the "blue molecule" or the clump of stuff at the beginning of the video would complicate the material at all. In fact, it would help to know the names!

  • @lorrainewands are u sooo gud n biology ..??? if sooo cud u xplain me sumthngz cz i seriousli din gt it @ ol aba it

  • @bmithaiwala yup! i'm amazing in biology! Let me know if u need help :)

  • @msc0328 thx 4 the explanation dude

  • @XxXdragurlifeXxX

    1 - It's politically incorrect to talk about these things.

    2 - the environmental protection agency requires tRNA be recycled when possible.

    3 - made in China.

    I am a genetic engineer.

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  • The movement and struture of the DNA molecule is quiet scary,disturbing!!!

  • Is the rna that is made tRNA or mRNA??

  • Thank you! My biology exam is drawing near, and this gave me a good overview!

  • Fantastic. Reminds me of PBS. I also wish they had more animations like this for other biological processes, especially the Calvin and Krebs Cycles.

  • gross but good video..

  • Amazing how complex this process is, and even more amazing how this is the very basics of the innumerable interactions between the billions of cells in our body.

  • I find this video hard to masturbate to

  • are our insides REALLY THIS creepy looking??

    

  • omg this is so cool, such a great video

  • This makes learning fun. I was actually awed and overjoyed to find out that the transcription process was that fast xD. lol, that was amazing.

  • Did anyone else notice that she said mRNA encodes U for T when mRNA actually encodes U for A on the DNA template strand?

  • @austin11235 she said that T is replaced by U in mRNA

  • this is so ridiculous, how does this work, who or what tells the moleculs to do this and that. it's so amazing

  • Biology test tomorrow, and this is all I need! (:

  • wow .. cool i got a little bit of understanding here , but great and detailed information .. thank you for these kind of videos , what could i possibly done without it .

    its in 3d and i am a visual person .. I hope this helps me develop a broader understanding .. :)

  • what is the 'blue molecule' called?

    

  • @doiiiiiiiiiii Its actually called RNA polymerase

  • @doiiiiiiiiiii I think it's RNA Polymerase, which translates the DNA into mRNA.

  • What exactly are these "factors" assembling at the start of the gene before transcription kicks off?

  • @Carlitosway86 "transcription factors" are molecules that bind to DNA and either promote or inhibit the recruitment of RNA Polymerase II to that area so that transcription can or cannot occur.

  • @msc0328 ok I dug around and found this " triggered when proteins called transcription factors bind to the promoter region of the gene" so in essence proteins, thanks for your explanation as well. Also if anyone is interested, recently this news was leaked regarding transcription (2nd news bit down) Hopefully we get to see this real-time footage very soon.

  • @msc0328 ok I dug around and found this " triggered when proteins called transcription factors bind to the promoter region of the gene" so in essence proteins, thanks for your explanation as well. Also if anyone is interested, recently this news was leaked regarding transcription (2nd news bit down) Hopefully we get to see this real-time footage very soon. Just type in "SCIENTISTS OBSERVE SINGLE GENE ACTIVITY IN LIVING CELLS" in any search engine.

  • @msc0328 ok I dug around and found this " triggered when proteins called transcription factors bind to the promoter region of the gene" so in essence proteins, thanks for your explanation as well. Also if anyone is interested, recently this news was leaked regarding transcription (2nd news bit down) Hopefully we get to see this real-time footage very soon. Just type in "SCIENTISTS OBSERVE SINGLE GENE ACTIVITY IN LIVING CELLS" in any search engine.

  • @msc0328 Ok so these transcription factors are essentially just proteins, thanks. I found some very interesting news regarding real time footage of transcription in a living cell, hopefully it gets shared with the public in the near future. :) It's very recent researched (published on Apr. 22 of this year) just search for "SCIENTISTS OBSERVE SINGLE GENE ACTIVITY IN LIVING CELLS" and you'll pull it up.

  • @Carlitosway86 my dick

  • in translation do the tRNA's always possess the anti-codon that pairs with the codon or are there errors?

  • wtf this is so shitty and creepy

    the woman's background voice is scary

  • Science and the human cell proves evolution is a bucket of bull!

  • @Treckorz ....how?

  • @Lightscribe225 Its all infront of your eyes mate.. i have been studying sciences for over 4 years and its just mind blowing and just look at all these videos of how everything is working at the same time and each function has a mind of its own.. immposible for it to all be by chance. There is so many more reasons.

  • @Treckorz Well when you consider that the cell has had billions of years of screw ups that died off, it doesn't seem so mind boggling. Besides evolution is happening right now with those steaks everyone eats.

  • @Lightscribe225 Thats a theory with no proof. They back the suffesticated cell the with "theory" "proof" that it happened because of so many screw ups, but there is no hard evidence for it. Trust me my friend im not little child im going onto doing my phd in pharmacy, and i tell you right now if all the pieces of the puzzle fit together i would of been a big believer of evolution, but they dont! I am very open minded and do my research and hardcore thinking. :) peace.

  • @Treckorz Of course it's theory. Nearly everything in science is theory. But it is accepted theory until something with more solid results knocks it off the pedestal. And the proof that it works is the fact it exists and the ones that didn't are now fossils buried in rock.

    If it ain't evolution that did this then what? And I'm also majoring in biology, going into radiology, so let's try and keep that out of the mix.

  • @Lightscribe225 I see where yo uare commig from, Il tell you something; i dont think that evolution did not take part at all, i think it did contribute to life in a way however i totaly disagree with the big bang theory and how the earth was created out of space and slowley life was formed etc. And that apes are a common ancestor i still havnt found hard evidence. There are people i kno who believe in evolution but at the same time believe in the 1 created of the universe a religion.

  • Great video, you can read and read and read the chapter on DNA, but when you see it in action like this, it really comes together. Thank you for posting this !!!! Was a great help. :)

  • I thought this vid was pretty cool cuz u don't realize the magnificence of our bodies function. I also take a personal interest in biology :)

  • this helped a lot. thank you. my bio is in for thursday :L

  • Is this how babies are made?

  • so the ribosome is basically an animal since it can translate? that is quite amazing since i thought the brain was the reason we have thoughts

  • Great graphics but isn't it "nucleotide" instead of "nucleic acid"? And what happened to the mRNA processing?!?

  • @allenglandlawns

    it got spliced out

  • So Atheist people your telling me that all of this just happens....there is no power up above that controlls this??......get outta here.......This is all God's creation

  • @Stanley81 you are ignorant beyond words, you do realize that you sound like a moron, if you ever went to school or studied at a higher level you would understand where the energy comes from, you're little mind is too ignorant to even ask that question, you just assume and think that god does anything you don't understand, go get an education then you can comment appropriately

  • Great

  • VIDEO IS GOOD BUT IT NEEDS THE NAMES OF THE ENZYMES FOR FULL UNDERSTANDING

  • the green triangles are the tRNAs

  • I got a 98 in bio this marking period thanks to this

  • This video just drives me crazy. It's like that voice is saying "See? We just explained the whole thing to you. No more questions please.......run along now."

  • Thanks!! i knew all that but it was a good rehearse!

  • I showed it to my teacher and classmates and all of us think it really helpful in explaining that lesson

    SO thank you soooooo MUCH for uploading it !

  • Its alot easier when you can see what happening.

  • I love this vid for teaching. It doesn't go into the hairy details that no one cares about. I think it is perfect!!

  • seriously you guys this video deserves an A+. cause of this i actually get it now. it took my teacher and classmates to explain but nobody did it as effective nor efficient as this did. PLease you guys learn of this video. educate yourselves and others ;]

  • this was a vety helpful video! I enjoyed the RNA polymerase zipping down the DNA, it looked like it was having fun hahaa

  • Thanks, I finally get it!

  • Thanks for the first transcription/translation video that made sense. Very well done.

  • by da way,how does the mRNA strand travels to the ribosomes on rough ER?And how the tRNA strands get attracted to the ribosomes??

  • how come the blue molecule,during transcription,rails through the DNA strand like that? Where does it get the energy from?It's a molecule...what are its components???

  • @Uchchash That molecule is RNA polymerase II - look it up on wikipedia because that question is a bit too big to answer here. It's energy comes from ATP (like many other enzymes in the cell). This particular molecule is *very* quickly hydrogen bonding to particular nucleotides and matching it up with their complementary letter to synthesize a string of RNA.

  • @Uchchash I believe the energy comes from the enzyme breaking that phosphodiester bond temporarily, but that could be incorrect

  • tyty

  • i hate biology

  • THANK U SO MUCH, this helped me like crazy,

    even though the beginning sorta creeped me out...

  • how many bases of the dna are copied via transscription a second (at the beginning of the vid)??

  • @TheSvenw007 I actually don't know the answer to that question, or an easy place to get the answer. There biochemical reactions are usually studied in isolation, and then the actual en vivo rates are estimated from factoring in real life variables. Why do you want to know how many nucleotides are incorporated per second?

  • @msc0328 yes, that is what i mean

  • @TheSvenw007

    I dunno how many nucleotides are copied for transcription per second but during translation, 2 amino acids are added to the chain per second in eucaryotes and 20 per second in procaryotes

  • @w1czr1923 thx

  • @w1czr1923 thx

  • @TheSvenw007 About 50 nucleotides per second. :)