i dont really understand the last part of ur video with gene regulation in humans can u please help?
Are the transcription factors made by the regulator genes? then do the transcription factors bind with the promoter which allows RNA polymerase to attach to the promoter, then the DNA folds back on its self to activate the RNA polymerase so it can make mRNA? sorry just got a bit confused..
I'm thinking that lac operon is supposed to be an example of a negative control rather than positive control... Correct me if I got it wrong, that positive control has to do with activators and negative control has to do with repressors. Whether the gene is switched on or off is termed induction or repression.
@yang94329 I think you are right. lac operon in the case of this video is an example of negative control. Mr. Andersen made a mistake here. The truth is that lac operon can be used as negative and positive control because it has both a represor and an activator. The activator is cap, which is activated when it binds to cAMP, and it facilitates rna polimarase to transcribe the genes
Excellent simplified description of these complicated processes. However, I do believe there was a minor error. According to my genetics professor at UCD and the textbook, the repressor protein interaction is considered a mechanism of negative control. Conversely, the cAMP-CAP complex interactions are considered a mechanism of positive control because the presence of the protein complex facilitates expression of the Lac operon.
Lac Operon is an example of negative control. Whether it's negative or positive is dependent on the regulatory protein, and in Lac Operon's case, LacI represses the transcription. Hence it should be negative, not positive.
Thanks for the video! Really helps me in my study of the Organisation & Control of the eukaryotic and prokaryotic genomes...which are chapters in the Singapore-Cambridge GCE 'A' Level exam :)
Your videos have helped me a lot, thankyou :)
sapphiremusic1993 1 hour ago
i dont really understand the last part of ur video with gene regulation in humans can u please help?
Are the transcription factors made by the regulator genes? then do the transcription factors bind with the promoter which allows RNA polymerase to attach to the promoter, then the DNA folds back on its self to activate the RNA polymerase so it can make mRNA? sorry just got a bit confused..
sapphiremusic1993 1 hour ago
yeah, can you just be my teacher?!? thank you so much!!! this made everything make sense!!!
lyndseyrox124 2 days ago
Great Explanation!
Christina100891 3 days ago
Oh my god. You just saved me on my test. THANK YOU.
ShadoFire 4 days ago
Very very helpful thank you <3 if you charged, I would totally pay you.
NatalyInsanity 5 days ago
I get it now thank u
NeroMasud 5 days ago
awesome vid
Bubakarrr 5 days ago
RNA polymerase needs to GET IT IN baby
ludachristo 6 days ago
you're awesome hehe!
joyap03 1 week ago
That was very useful!!! Thank you! These video are great!
Sylar6 1 week ago in playlist AP Biology Video Essentials
Awesome ! this video helped me alot. I understand much better know wohoooo :D
Awesomlyawesomeful 2 weeks ago
This video, is fabulous.
BeccaCatharine 3 weeks ago
tomorrow is my test i think i had a grip on this. thanks to you!
lychee159 3 weeks ago
You're video was extremely helpful thank you for putting of up... :)
aflint08 3 weeks ago
thank you, really helped video..especially two days before exam :)
sluchatky 3 weeks ago
Thanks! This Helped ALOOOT!!! ;)
Kubalikhan 1 month ago
Comment removed
Kubalikhan 1 month ago
As a student going for a masters in biochemistry I couldn't do without videos like these. In other words yes it was very helpful.
ForYeensSake 1 month ago
this mother fucker should be my biology teacher
SterlingDAman 1 month ago
LAC operon is negative control because it prevents transcription by a repressor binding :/
samasoftley 1 month ago
5 biology teachers are jealous that Mr. Andersen can teach and they can't.
rawrl2121 1 month ago
fast and easy way to understand the concept! great! thank you so much!
ErValentina 1 month ago
this guys my teacher in real life for AP Bio...hes so great, its my favorite class of the day.
ImTheSleepless 1 month ago
@ImTheSleepless You lucky son of a b*tch turns out watching this video helped more then 2 lessons at school...gosh
Taziod 1 month ago
screw notes, i got youtube
ct501st 1 month ago
Having a test in 1 hour on this....GOOD MAN!
MrJimmycomaskey 1 month ago
Thank you. But when am i ever going to use thing is life?
roflwilwin 2 months ago
@roflwilwin when you drink milk :P
GuschtlD 1 month ago
@roflwilwin when you have a biology test that is about gene regulation
Taziod 1 month ago
Thank you really helpful thanks for uploading
haroonsafi1992 2 months ago
I'm glad I found this vid.. save me from reading those crap..
korewa444 2 months ago
thanx... this is really very helpful.....
rekhamanidas31 2 months ago
omg thank you so much I was reading my textbook and it was not making sense at all. now I understand!
LikeKiraKira 2 months ago
you are the fkn man,,, thank you,
yja817 2 months ago
Very helpful:)
hegejkunden 2 months ago
YOU ARE AN EXCELENT TEACHER THANK YOU MR. PROTEIN I LOVE YOU
GuilhermeRochaDIRT3 2 months ago
this is fantastic. thank you
bichstewie 2 months ago
Very good job! THANKS!
eversmarketing 2 months ago
Thanks very much. This really helped me understand the regulation of genes
sweets00002 2 months ago
10,822 views, and 28 comments. That's crap. You have a wonderful way of describing things and I hope you understand that your efforts matter.
ufo8mykat 2 months ago
I'm thinking that lac operon is supposed to be an example of a negative control rather than positive control... Correct me if I got it wrong, that positive control has to do with activators and negative control has to do with repressors. Whether the gene is switched on or off is termed induction or repression.
yang94329 2 months ago 2
@yang94329 I'm pretty sure you are right. A negative control is always on unless turned off by a repressor
ChickaDeidz 2 months ago
@yang94329 I think you are right. lac operon in the case of this video is an example of negative control. Mr. Andersen made a mistake here. The truth is that lac operon can be used as negative and positive control because it has both a represor and an activator. The activator is cap, which is activated when it binds to cAMP, and it facilitates rna polimarase to transcribe the genes
gregoryvass1 2 months ago
@yang94329 no you are correct I'm convinced :P
samasoftley 1 month ago
thank you so much for an amazing video! gene regulation makes so much sense now!! you're so awesome!! thanks so much :))))
missstrawberryish 3 months ago
I dont understand why this video has a dislike .. he explains it nicely and clearly .. aah some ppl! :S
Darkcurse101 3 months ago 21
@Darkcurse101
cuz they're retarded
i personally thought the video did an amazing job in explaning
Jaesango 2 months ago
@Jaesango I totally agree man.
Darkcurse101 2 months ago
@Darkcurse101 probably because it was the one person who realised mr Anderson's mistake...LAC operon is negative control
samasoftley 1 month ago
I like the way you explain it. Thanks for doing all these vids.
ByRecentDesign 3 months ago
why do i even go to school when i can learn everything on the internet?
Thank you, you helped a lot. :)
Flotty93 3 months ago 39
Comment removed
piojita63 3 months ago
Excellent simplified description of these complicated processes. However, I do believe there was a minor error. According to my genetics professor at UCD and the textbook, the repressor protein interaction is considered a mechanism of negative control. Conversely, the cAMP-CAP complex interactions are considered a mechanism of positive control because the presence of the protein complex facilitates expression of the Lac operon.
lincolnbball10 3 months ago
Dear Mr. Anderson, you're a hottie. and an awesome speaker. thanks!
nchilcutt6 3 months ago
Hahaha, right as he snapped, my computer spontaneously shut down...
irishactingboy 3 months ago
thanks, this help alot
lyac 3 months ago
thank you! I learned a lot :)
mluca3120 3 months ago
This video was amazing, ive been looking everywhere for this and couldnt understand it until now, so thanks :)
Becklesxx 3 months ago
very helpful! :)
andreashippey 3 months ago
thanks :)
rigaraj 3 months ago
(: very good teacher
kafooxD 3 months ago
In this case, wouldnt the repressor be considered negative control?
conroth123 3 months ago
Thank you! Mr. Anderson. You are a good teacher.
Student1911 4 months ago
thanks alot :) i have been searching everywhere for this on youtube and your way of explaining this was perfect :)
SwIfTyRoXMySoXIeS 4 months ago
Thank u Sir, very simple and helpful. May the Lord Jesus bless u abundantly. Thank u.
raghunice 4 months ago
Best biology video I've seen (I usually watch Khan Academy)
jack40k 4 months ago
You Sir are Amazing. Thank You!!
ilselpz 4 months ago
Lac Operon is an example of negative control. Whether it's negative or positive is dependent on the regulatory protein, and in Lac Operon's case, LacI represses the transcription. Hence it should be negative, not positive.
dldlflfl 4 months ago
Thanks so much!!! :D
Bagal92 4 months ago
I love you Mr Anderson!!!
TheMordyS 6 months ago
very helpful!! i like the process of teaching. Thanks.
kal41107 7 months ago
This really helped. I'm doing NCEA Level 3 biology in New Zealand. Thank you for the help. :)
ParanoiaDestroyah 7 months ago
@ParanoiaDestroyah ahh me too :)
SwIfTyRoXMySoXIeS 4 months ago
Thanks for the video! Really helps me in my study of the Organisation & Control of the eukaryotic and prokaryotic genomes...which are chapters in the Singapore-Cambridge GCE 'A' Level exam :)
YudhishthraNathan 7 months ago