I am misskitka on tu. If I use synthetics for 2 weeks I become hypo unaware, get terrible neuropathy, and the list of adverse affects is endless. Using Hypurin pork I am healthy and after 53 years with type one this next summer have no complications in the least. This has to mean something. I tested negative for c-peps on synth and positive with Hypurin. I agree that the intentional removal of c-peps is gross and disgusting. I test only 2-3 times a month.
People who do not have diabetes a) they do not develop diabetic complications and b) they have normal levels of c-peptide. People with type 1 diabetes often show 'undetectable' levels of c-peptide because their islets do not produce insulin. People with type 2 diabetes show excess amounts of c-peptide because their islets produce insulin but their cells do not allow it either insulin or c-peptide to be used sufficiently.
c-peptide indicates that your islets are producing insulin. Often times, with Type 2 diabetes - it shows a high level of c-peptide because your islets are producing a lot of insulin to manage blood glucose but your cells are NOT allowing c-peptide to land on their receptors to provide the protection from diabetic complications. It's similar to the problem of insulin resistance.
No I used analogues from July 1984 (Humulin) unril May 2007. I started using Hypurin Regular that month and haven't changed since. I was mistaken as to the 'removal' of C-peptide in analogues. They don't use the "c-peptide" in their manufacturing process. The yeasts or e.coli are only given the A and B peptide of insul to reproduce. The c-peptide in animal insul is not the same structure as human c-peptide and is not effective in the same way ;(
There is alot of controversy about this that is for sure. I have never use porcine or bovine insulin, and have't researched them much. Is the c-peptide remvoed from these typically as well? BTW, do you change your insulin often? I tend to mix it up and switch my basal and bolus insulins every few months or so. Great vid.
Hey Allie :) Just wanted to drop a message to say how facinating your videos are, and how glad I am that you post them for all us diabetics to see. I have only seen a couple of videos so far, but I subscribed instantly. I am a 19-year-old girl from the UK, and we just don't seem to get such detailed info over here. I've been diabetic since I was six, and I was lucky enough to have a 'honeymoon phase' where I produced insulin again a couple of years after diagnosis...
If anyone has been wrongfully terminated by Novo Nordisk, please respond on this blog. I heard they fire people that are labelled "unwanted", imagine that? They need to treat people more like humans.
Type 1s are a captive audience. Only 10% of Type 2s inject insulin. C-peptide repairs the effects of insulin carrying glucose out of the blood and into the cells and Type 2s injecting insulin still make insulin -- so they h ave C-peptide. This is why Type 1 complications occur in CELL WALLS and Type 2 complications occur in clots in the heart and brain -- TOO MUCH INSULIN! The only thing that protects Type 2s from complications is less blood sugar in the first place.
So big farma are against T1 Diabetics? some things in the body are useless , like C protein once insulin were out Beta Cells. If not big farma will make the insulin mix with C protein.
And I know a lot of things that Newton don`t , relative teoria for exemple.. ;P
Research is proving that intensive blood sugar control does not avoid complications for people with Type 1 diabetes -- it only prolongs the amount of time they take to develop. I don't consider than advantageous. I consider it a business decision in pursuit of the whole diabetes market. That is nefarious and criminal to Type 1s - especially since Lilly, Novo and Avntis have NO interest in making C-peptide available to US. I've asked!!
Since when does a God-given piece of the body get "discarded" like trash? C-peptide has a FUNCTION of protecting us from the effects of INSULIN. Do you not believe in science? Newton's laws of motion explains the relationships between the forces acting on a body and the motion of the body - an equal and opposite reaction. Or do you know something He or Newton didn't know? Big Pharma is throwing-out C-peptide like trash. IT IS NOT TRASH!
So big farma are against T1 Diabetics? some things in the body are useless , like C protein once insulin were out Beta Cells. If not big farma will make the insulin mix with C protein.
And I know a lot of things that Newton don`t , relative teoria for exemple.. ;P
Allie,
I am misskitka on tu. If I use synthetics for 2 weeks I become hypo unaware, get terrible neuropathy, and the list of adverse affects is endless. Using Hypurin pork I am healthy and after 53 years with type one this next summer have no complications in the least. This has to mean something. I tested negative for c-peps on synth and positive with Hypurin. I agree that the intentional removal of c-peps is gross and disgusting. I test only 2-3 times a month.
Be well and take care.
Don
pdp1170 2 weeks ago
insulin resistance indicates an excess amount of (unused) insulin in the body and it will show up on blood tests.same with c-peptide:
c-peptide resistance indicates an excess amount of (unused) c-peptide in the body and it will show up on blood tests.
AllieBeatty 10 months ago
People who do not have diabetes a) they do not develop diabetic complications and b) they have normal levels of c-peptide. People with type 1 diabetes often show 'undetectable' levels of c-peptide because their islets do not produce insulin. People with type 2 diabetes show excess amounts of c-peptide because their islets produce insulin but their cells do not allow it either insulin or c-peptide to be used sufficiently.
AllieBeatty 10 months ago
c-peptide indicates that your islets are producing insulin. Often times, with Type 2 diabetes - it shows a high level of c-peptide because your islets are producing a lot of insulin to manage blood glucose but your cells are NOT allowing c-peptide to land on their receptors to provide the protection from diabetic complications. It's similar to the problem of insulin resistance.
AllieBeatty 10 months ago
Let me say this again...I'm over the limit of C-peptide and my insulin is over as well.
Rob2977 10 months ago
I'm pretty lost with this C-peptide...I went had some blood test done and it seems
I have a very high c peptide but a normal glucose...anybody have any ideal on this?
Rob2977 10 months ago
No I used analogues from July 1984 (Humulin) unril May 2007. I started using Hypurin Regular that month and haven't changed since. I was mistaken as to the 'removal' of C-peptide in analogues. They don't use the "c-peptide" in their manufacturing process. The yeasts or e.coli are only given the A and B peptide of insul to reproduce. The c-peptide in animal insul is not the same structure as human c-peptide and is not effective in the same way ;(
AllieBeatty 1 year ago
There is alot of controversy about this that is for sure. I have never use porcine or bovine insulin, and have't researched them much. Is the c-peptide remvoed from these typically as well? BTW, do you change your insulin often? I tend to mix it up and switch my basal and bolus insulins every few months or so. Great vid.
HaligonianType1 1 year ago
Hey Allie :) Just wanted to drop a message to say how facinating your videos are, and how glad I am that you post them for all us diabetics to see. I have only seen a couple of videos so far, but I subscribed instantly. I am a 19-year-old girl from the UK, and we just don't seem to get such detailed info over here. I've been diabetic since I was six, and I was lucky enough to have a 'honeymoon phase' where I produced insulin again a couple of years after diagnosis...
MadassG 1 year ago
SYMLIN=C-peptide.....if that helps. Although it is not a component of insulin, it is available.
diabeticgonewild 3 years ago
If anyone has been wrongfully terminated by Novo Nordisk, please respond on this blog. I heard they fire people that are labelled "unwanted", imagine that? They need to treat people more like humans.
Stix4568 4 years ago
Type 1s are a captive audience. Only 10% of Type 2s inject insulin. C-peptide repairs the effects of insulin carrying glucose out of the blood and into the cells and Type 2s injecting insulin still make insulin -- so they h ave C-peptide. This is why Type 1 complications occur in CELL WALLS and Type 2 complications occur in clots in the heart and brain -- TOO MUCH INSULIN! The only thing that protects Type 2s from complications is less blood sugar in the first place.
AllieBeatty 4 years ago
So big farma are against T1 Diabetics? some things in the body are useless , like C protein once insulin were out Beta Cells. If not big farma will make the insulin mix with C protein.
And I know a lot of things that Newton don`t , relative teoria for exemple.. ;P
urufam 4 years ago
Research is proving that intensive blood sugar control does not avoid complications for people with Type 1 diabetes -- it only prolongs the amount of time they take to develop. I don't consider than advantageous. I consider it a business decision in pursuit of the whole diabetes market. That is nefarious and criminal to Type 1s - especially since Lilly, Novo and Avntis have NO interest in making C-peptide available to US. I've asked!!
AllieBeatty 4 years ago
this is not correct, intensive blood sugar control can reduce de incidence of complications, ergo some patients didn't develop complication at all.
Anyway C peptide is discarded once insulin leaves the Beta-Cell and goes into blood stream.
urufam 4 years ago
Since when does a God-given piece of the body get "discarded" like trash? C-peptide has a FUNCTION of protecting us from the effects of INSULIN. Do you not believe in science? Newton's laws of motion explains the relationships between the forces acting on a body and the motion of the body - an equal and opposite reaction. Or do you know something He or Newton didn't know? Big Pharma is throwing-out C-peptide like trash. IT IS NOT TRASH!
AllieBeatty 4 years ago
So big farma are against T1 Diabetics? some things in the body are useless , like C protein once insulin were out Beta Cells. If not big farma will make the insulin mix with C protein.
And I know a lot of things that Newton don`t , relative teoria for exemple.. ;P
urufam 4 years ago
Interesting. But type 1s are the majority of insulin users, even though we're not the majority of diabetics.
Pharmaceutical insulins are improvements for us T1s not because of the c-peptide but because of the duration of action.
lantusappreciation 4 years ago