@FortuneFavorsPrep According to my knowledge, I want to point out that Triacylglycerol lipase is not the ONLY regulatory enzyme for beta oxidation. Carnitine acyltransferase I is also a regulatory enzyme that facilitates the entry of fatty acyl-CoA into mitochondria where beta oxidation can only happens. When there is high blood glucose, malonyl-CoA inhibits carnitine acyltransferase I to stop beta oxidation. Please tell me if I am right or wrong. By the way, this video really helps me a lot.
I just wanted to point out what I think is an oversight in the tutorial. Overall, a great tutorial, but at the beginning of fatty acid synthesis, I believe that malonyl-CoA is going to undergo a decarboxylation reaction. That explains the decreased number of total carbons from 5 to 4 (not including the R group). It also explains the electrons that bond to the activated acetyl group. Once again, great tutorial, but just wanted to point out that detail.
@TheMrCGraves This is a great point however I was trying to give a very general overview of the process of fatty acid synthesis, you are correct that it is malonyl-Coa that is decarboxylated (loss of CO2). I want to do a video specifically about fatty acid biosynthesis I was doing this just more as a comparison showing how the two pathways compare to each other in very general terms.
Thank you. You are better than my instructor. -3
iVi07MMAD 1 month ago
@FortuneFavorsPrep According to my knowledge, I want to point out that Triacylglycerol lipase is not the ONLY regulatory enzyme for beta oxidation. Carnitine acyltransferase I is also a regulatory enzyme that facilitates the entry of fatty acyl-CoA into mitochondria where beta oxidation can only happens. When there is high blood glucose, malonyl-CoA inhibits carnitine acyltransferase I to stop beta oxidation. Please tell me if I am right or wrong. By the way, this video really helps me a lot.
cheung3305 3 months ago
Comment removed
cheung3305 3 months ago
I just wanted to point out what I think is an oversight in the tutorial. Overall, a great tutorial, but at the beginning of fatty acid synthesis, I believe that malonyl-CoA is going to undergo a decarboxylation reaction. That explains the decreased number of total carbons from 5 to 4 (not including the R group). It also explains the electrons that bond to the activated acetyl group. Once again, great tutorial, but just wanted to point out that detail.
TheMrCGraves 3 months ago
@TheMrCGraves This is a great point however I was trying to give a very general overview of the process of fatty acid synthesis, you are correct that it is malonyl-Coa that is decarboxylated (loss of CO2). I want to do a video specifically about fatty acid biosynthesis I was doing this just more as a comparison showing how the two pathways compare to each other in very general terms.
FortuneFavorsPrep 3 months ago
can you do a vid on citric cycle and kerbs cycle and glucogenolyse and those thing thx
masterwizard155 4 months ago