Comparing E2 E1 Sn2 Sn1 Reactions

[2StepMurder]

sal for president

[amcrasto]

GREAT VIDEO

[09nabila]

lol, our pot?? ahaha, thanks man! you're awesome! so much sense! :D

[dyepribudoy]

"The beta makes it a little dirty" lol.

[W00t57]

I Like your pictorial view of SN2, SN1... But they seem very jumbled and disorganized. Still great video

[Katsumato0]

12:26 beast looking shoe

[adrianus1christopher]

TWO THUMBS UP FOR YOU!! it's a really excellent tutorial video! thank you so much!! keep making videos like these! LOL. God bless you!

[enjoykenny]

those dirty betas... >:]

[Lawtonianbabygirl8]

THANK YOU SOOOO MUCH!!!! I LOVE YOU!!! Lol..I'm about to keep watching this and your other ones until they sink in!

[WooCla]

Ugh. Getting myself to click this video to study for a test is like trying to study for any other test; it takes a lot of will power.

But as soon as I hear your voice, I think "...this is actually interesting...and doable..."

[westboarder]

What if we had a tertiary alpha carbon reacting with a strong base?

Would E2 still dominate?

[nightstar1219]

Thanks I'm going to do great on these questions for the test

[liagiba10]

THANK YOU!!!!

[Gogaa91]

i need this for PCAT * *

[zams650]

Excellent, extremely clear presentation. Thank you for taking the time to post this!

[unnecessaryremarks]

how does this guy know so much...........

[michals000]

your videos have helped me soo much this acedemic year. I keep telling my boyfriend that I want to send this person (you) a big fat thank you card! you're awesome and you explain things exactly how they are without complicating things. THANK YOU VERY MUCH. ITS PEOPLE LIKE YOU WHO MAKE THIS A BETTER WORLD FOR EVERYONE :)

[Everett345]

@michals000

maybe you should be sucking his dick rather than tellin him about these little things he doenst care about? Gl with ur relationship honey

[nhssoccer05]

apparently they each have two hydrogens on them

[tennisl12]

HOW CAN U TELL IF SOMETHING IS A BASE OR A NUCLEOPHILE? I'm so confused right now...

[kingbiscuit28]

@tennisl12 @tennisl12

Nucleophile is an Electron Donor (Base = Nucleophile) they are the same thing

Electrophile is an Electron Receiver

I despise the term nucleophile!! Everything should be put in perspective of electrons. IMO

[flcl49]

@tennisl12 a base is anything with a - charge that moves in to attack, so in essence it's a nucleophile. but for example if u have a substance say ch3Br reacting with H2O; in this case the O is what will be attacking the C and it is considered a nucleophile, but it is a weak base

[junior1984able]

bromide has one extra valence electron on its own ; right??

[kingbiscuit28]

@junior1984able

It's natural state is 7 electrons, but it really wants to complete the octet so it usually steals the 8th one from somewhere like a hydrogen atom that will then be + due to a lack of one electron

[junior1984able]

can any two atoms with pairing valence electrons combine to form a bond??

[19shaggy88]

i wonder how man of the 19k views would have failed their test if not for you

[PawprintsAngela]

THANK YOU. YOU HAVE JUST SAVED MY FUTURE IN MED SCHOOL. :)

[sharma1337]

@PawprintsAngela

Didn't you need to understand for mcat to get into MED SCHOOL?

[cuttingbeauty1]

@PawprintsAngela ME TOOOOO!!!!!!! I take my MCATs SOON!

[urdouchbag]

thank you...

lol...i didnt realize it was a complete separate video...

[urdouchbag]

i may sound silly...but..what is a concrete difference between an nucleophile and a base....?

[voutasaurus]

@urdouchbag check out his previous video on the difference: It's called Nucleophilicity vs. Basicity. (Sorry, for some reason Youtube isn't letting me post the link)

[urdouchbag]

you are a very dedicated teacher!

[Masterofchaos91]

Nice explained :-) which program do u use?

[lidyaFACE]

i have my orgo final tomorrow and you cleared up every confusion i had! thank you! btw, how would i know if something is a strong or weak nucleophile?

[ASSHOLELA]

hey which is faster E1 or E2 and what depends which is faster?

[halogrenadier]

@ASSHOLELA E1, it only has one rate determining step

[marauderfh]

@ASSHOLELA Speed of the reaction depends on a ton of things. Primarily the substitution of the site of action, solvent, concentration of reactant(s) depending on the modality. 

To say one is faster than the other is never accurate without specifics.

E2 only has one rate determining step - in fact it only has one step! E1 only has one rate determining step, but it has two total steps, so the initial reply you got is incorrect.

Basically tertiary it will be E1. Primary/methyl for E2.

[jordanhop2]

In both this video and the next the DMF is present but I don't see how it's used in the reaction or product. Does it have to be present? Is it being used? Why isn't it's components involved in the mechanism?

[halogrenadier]

@jordanhop2 DMF is a solvent, it only determines the protic-ness, and the difference between 2- and 1-series reaction

[stigybirdable]

I love this man, organic test tomorrow

[jaffey2006]

I liked your video a lot, but this is a reaction that will favor an E2 mechanism, and less so Sn2. CH3O (-) will be favored in this case due to it's extreme basicity. Since the alkyl halide is secondary, (or I should really say, since the carbon it is attached to is secondary), and the nucleophile is a powerful base, E2 will be dominant. Now, this is not to say that Sn2 will not occur, it absolutely will, just in lesser quantities. If the N.F was a WEAK base, Sn2 would predominate.

[henik9]

Mr. Khan you are a gentleman and a scholar! You make education fun.

[dalcde]

Is it possible that the methanol reacts with that cyclopentene to form what we get in the Sn2 reaction?