Sliding Filament

[pelicanus11]

most men think with their penises !

[ChicaWolverina]

Anemic micing.

[Lixinim]

This helped me a lot, thanks :DD

[MegaPaddy86]

Really great, clear video and I found it just in time for exams, thank you!

[MimiMercy]

Thank you very much.

[sosaismary]

...cool.

[AZNKC]

This is for the on-going battle about penis being a muscle that revenger must fight all by himself. The penis is NOT a muscle. It enlarges due to the blood being pumped into 3 sponge like structure of the shaft of the penis. ok so why is it that you can control the excretion of urinating or jizz is its not volunteer muscle control? You are actually controlling other muscles that make sphinters contract or relax in your genitals.

[bumsukify]

BAXSTER!!

[lynn2beme15]

Wow. I love it. Very simple and easy to comprehend

[pain2758]

thanks! i had to do this for my course and i think i understand it abit better now

[bearnextdoor1]

Really great video !!

[DudeWTF092]

This actually helps! =D

[chriscarter62hdn]

Dont you to mean adenosine triphosphate, not adenine?

[0opisceso0]

What does the ADP and Pi stand for? PM me or reply on here, I don't mind. I need to know before the end of the weekend, thanks a bunch!

[hafaball]

@0opisceso0 Adenosine diphosphate

[Jonesle90]

@0opisceso0 ADP = adenosine diphosphate, and Pi = inorganic phosphate.

[0opisceso0]

Thank you for this video, it's really helped me to understand the sliding filament theory! The myosin heads look like lobster claws attaching themselves to the sea bed and then moving forward. XD

[ssj3jerome]

Quick, easy and 3d models always help explaining it. Though I wonder how myosin heads are able to first extend and stroke when ADP is spend?

[hafaball]

why does she sound so scary :|

[On5Jello]

Thanks!! This is the most accurate video I've found so far on the sliding filament theory since the video shows the Pi coming off allowing binding onto actin & then ADP coming off to cause the power stroke.

Other videos show it as ADP + Pi coming off at the same time causing the power stroke or the Pi isn't shown at all.

If this video is to be improved in any way, my only suggestion is to show ATP coming in causing the myosin head to detach from the actin a little more clearly.

[enchantedtomeetyouu]

Anything wrong with 2:58?

[MrRedlet]

@enchantedtomeetyouu clearly :P x

[snakeanassnake]

Sara you go gurrrll

[zarine199]

the sound isnt clear

[goofiuss]

yeah. adenine is a nitrogenous base of nucleic acid. totally not the same stuff at all.

she should be saying ADENOSINE di or triphosphate.

[Th3EnlightenedOne]

It sounds like you're saying adenine triphosphate/diphosphate, but isn't it adenosine triphosphate/diphosphate? I don't know, so I'm trying to figure out what is the correct term before I use it in a research paper.

[gunjan0808]

@Th3EnlightenedOne its triphosphate

[Th3EnlightenedOne]

@gunjan0808 Yeah, I got the triphosphate and diphosphate distinction. The word "adenosine", when she says it; it sounds like she's saying adenine. Isn't there a difference between the two?

[Mrmoc7]

This video was quite helpful! The concept isn't difficult to understand, but when you're in med school, the goal is to understand it as quick as possible! Haha, love this animation guys, thanks!

[TheRalphrochie]

hoopefully this would help me to get perfect in our test next week

[benmcc22]

Dr.Andrew Huxley is a BOSS

[NuwaniGomage]

thanks =)

[More2Life21]

Great video!!!!!

[movildsv]

@Kellogg114 you are mistaking.

[porschedemon1]

thanksss

[jalfinator]

sounds is quiet even on full, my laptop sounds is quiet but ...

[OverflowC]

is there a neurotransmitter involved anywhere?

[brainmoss]

@OverflowC Yes, when a nerve impulse reaches the muscle a neurotransmitter is released. This causes the release of the calcium ions you see at 1:15 in the video.

[stealthtank91]

great video! its adenosine di-phosphate not adimine di-phosphate though right? that got me confused...

[jdm142]

@stealthtank91 right

[lokithegreat157]

VERRRRY GOOD WORK YA...!!!!!

[googleflex]

genius man,

[clarinetmaniak]

amazing video. thanks!

[MyiTheMage]

Sara Egner has a strangely shaped skull

[primalsledge]

this may have saved my education.

[rahed53]

great video, good job

[specialblend58]

great video! thanks much

[lukethompson18]

and thats how i met your mother

[waakkeuppp]

very good!

[aalibobally333]

this is the best video.



[colepeters123]

so does the miosin head drag the actin or does it crawl up the actin?

[zorgen12]

Poor speaker. She needs to speak up. Knows the material but I had to crank up my volume to hear her. Great video and material but needs a male speaker, someone who has a good speaking voice..she does not.

[kennybluebird]

@zorgen12 agreed!!!!

[pasta23]

you messed up!

the energy released from the dissociation of ATP is what attaches the myosin head to the myosin-binding site on actin. Then, the inorganic phosphate is released from the myosin, which initiates the power stroke. According to the physiology book produced by Human Kinetic Publishers.

[sweetassweat]

Why Is Calcium Released?

[Moritzx]

@sweetassweat when an action potential (nerve impulse) reaches the muscle cell membrane (sarcolemma), calcium channels open in the neighbouring sarcoplasmic reticulum, causing the calcium which was previously stored inside the sarcoplasmic reticulum to be released to the sarcomeres. The calcium channels open because the change in membrane potential triggers it (it's normally a negative voltage but the nerve impulse makes it positive).

[sweetassweat]

Why Is Calcium Released?

[lilliesNbees]

my book talks about T tubules making the sarcolemma release the calcium. where does this step play in the contraction of the sarcomere?

[TheLethargic21]

@lilliesNbees

I am guessing you meant sarcoplasmic reticulum (i.e. the modified muscle fiber endoplasmic reticulum) instead of sarcolemma which is the plasma membrane.

The order is: 1)AP from presynaptic cell (i.e motor nueron) causes 2)post-synaptic potential in muscle fiber 3) If that PSP causes sufficient depolarization it generates an AP in the muscle fiber. 4) Causing T-tubule (an extension of the sarcolemma) depol. 5) T-tuble depol. causes a sarco retic to release Ca2+ intracellularly

[assmayonnaise]

Most men would consider the penis to be the most important muscle in the human body

[AirPlaneNinja]

thumbs up for penis muscles! woo!

[electheded]

Very informal

[assmayonnaise]

is this what happens when my peepee gets bigger??

[revenger20012]

@assmayonnaise

no moron

this is in ur muscles not ur penis

which clearly ur penis is not a muscle

[assmayonnaise]

@revenger20012

I thought the penis was the love muscle???

[revenger20012]

@assmayonnaise it is not muscle for god sake

the blood gather in ur penis and then makes ur penis gets bigger which clearly different from the muscle 

[johnson8918]

@revenger20012 Really? Hmm... I thought that when your penis muscles relax, u let out urine. At least that's what my sex ed teacher taught me..

[revenger20012]

@johnson8918 there is another thing control ur urinating

yea there's a voluntary muscle it can close/open ur urethra tube so u can excrete urine BUT it is not part of ur penis it is between ur urethra and ur bladder..

[hilda274]

@revenger20012 Your penis is a muscle, you ignoramus.

[anya2396]

@revenger20012 it is made up of tendons :)

[ramesjowe]

@revenger20012 as far as i am concerned your penis is definitely a muscle unless it doesnt work for you?

[revenger20012]

@ramesjowe asshole

have u ever seen a muscle when it enlarge, it gets x4 or x5 times bigger ?

in histology it called erectile sheet not a muscle

even it is control differently by nerves

[teenybod]

Fantastic. Thanks so much!

[iono101]

Where'd all the ATP come from?

[alexandrahanson]

@iono101 The ATP comes from the mitochondria in the muscle cells

[CherryPi420]

Excellent video! Thank you so much!!

[vtecjenny13]

Great video! Thanks so much!

[mamahv]

now I get it. This is the best video Thanks!

[ahdhffkdyd1]

this shit is so good. best video

[chrissline77]

Thanks to Youtube and videos like this there is no way anyone should be failing biology, anatomy, or physiology in this day and age.

This video explained to me in 3 minutes what I had trouble understanding after reading a whole chapter. And it wasn't even painful.

Beautiful job whoever produced this.

[akayk]

Great job with this, you made it very easy to understand

[AdrenalineHeat]

amazing video, the best one out of all of these, i actually learned everything i needed to know for this theory in my exercise science class.

[siedaht1]

omg thank u soo much

[MythmanS2playerWee]

nomnomnom...

This video actually helped a bit.

Used it for my homework (^_^)

[campify]

I agree with kayateia below; "GO Sara!" What an excellent video! Great animations and SUPERB narration! Absolutely brilliant!

[mandbx]

this is brill! thanks!

[harleychic970]

Great video!! Narration & animation makes this theory very simple to understand.

[SteelDetailer]

What's "adnean" triphophate and diphosphate?? My books call it "adenosine" tri and diphosphate... Otherwise, good video.

[mandbx]

yeah mine to, but i think its pretty much the same thing...

[mcgroarm]

adenosine triposphate (ATP) is made up of adenine and 3 phosphates

adenosine diphosphate (ADP) is made up of adenine and 2 phosphates

just a different way of saying the same thing as your book

[SteelDetailer]

@mcgroarm - I was thinking that was probably the case...thanks for confirming that!!

[verygoodbrother]

top notch

[kayateia]

Go Sara! ^_^