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From: TEDtalksDirector
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  • If everything turns red you're doing something wrong.

    How's that for colour-coding?

  • I really hope this works!

  • 7 dislikes think they will never get cancer in their lifetime!

  • thank you for sharing

  • Immensely informative! Thanks for sharing!

  • 1. Would it be possible to use recombinant DNA to modify white blood cells via in vitro to be directed to the florescence? For example: use a wet lab to modify CD8 to be directed to the florescence molecule for possible destruction.

    2. Once the fluoresces molecule is cleaved at contact with desired tissue. Could the anion portion of the tracer be tagged in use to activate a drug which is free floating in the cytoplasm? This way the drug is only activated at the site desired.

  • this is outstanding; i love it. way to go. as a pathologist, i know what is that mean. great for medicine...so called "best medicine"...

  • Making sense to me! She's vietnamese! Great

  • This is amazing! It is obvious that technology will produce better results in excising tumors and minimize inadvertent injuries in the OR. It's a shame that funding for such endeavors may be difficult, since drugs for one-time use are less likely to be developed. With the appropriate funding anything is possible however.

  • Hope in the near future this technology can tag somenew color materias to our contrast medium, so we radiologist can point out what happen in the body before surgery. LYC (TW)

  • being in my surgery rotation now I envy next generations as i see the future of surgery that 5 years later our fellows will not have to memories anatomical variation of body structures :@ :@ :D

  • i am going to work in cornell as research assistant on same concept..in surgical oncology ..awesome..

    nicely explained..

  • thaaaaaaaaaaaaaaaaaaaaaaaaaaaa­aaaaaaaaaaaaaaaaaanx doctor

  • vietnamese ftw

  • @vietvipp

    Vietnamese-American

  • I love that technology like this has come to be developed! Development is needed for sure but imagine the change of accuracy and correct surgeries. Fantastic! P.S. Not even going to deny that these technological developments make my dreams of a scifi future totally possible. :P

  • Comment removed

  • This is epic

  • American Vietnamese on TED, I like the video with pride :)

  • How about realtime mri or cat scans for better visualisation techniques for surgeons to see operatable regions better or maybe realtime higher quality colour 3d ultrasounds as well as colour microscopes improving better instrumentation and visual systems.

  • Imagen an emo surgeon in the operating room doing 2 operations.

  • Love, but it would have hit home even more if she wore a neon green dress

  • I'd do her

  • Knowledge is power, it's less nerving when you actually know what's going on what you're dealing with, especially when your health is at risk. Fuck belief and faith, those are for the weak.

    It's ironic that they had an operating room on top of a fucking church building, hypocrisy right there!

  • People in the audience feel like theyre going to puke,

  • wow, will probably be in hospitals within 10 years...

  • wonderful discovery. a holy discovery

  • Damn this is cool. Things like this are why I love TEDtalks

  • G E N I U S

  • Can this help cut out Lois Griffin singing annoying tumor?

  • @skillbill83 im a tumour im a tumour im a tumour :D

  • I really wish TED had more more views, this is important.

  • I felt like a football fan cheering for their favorite team to win during the superbowl! BRILLIANT!

  • Damn, after watching the thing I was clapping to the screen

  • Comment removed

  • She comes from Viet Nam

  • her voice sounds like its gonna break sometimes which is quite annoying tbh, but good discovery nontheless.

  • Just when you think you're smart... an Asian makes you look dumber than a doornail.

  • why isn't this technology in hospitals now

  • Why don't you go a step further and develop a chemical that can destroy the cancerous cells instead of illuminating them? Great job anyway :-)

  • @vpfaiz Yeah, that's being researched. Of particular interest is a targeting molecule which only activates when hit by a specific light - put that in the system, wait for it to accumulate in the tumours, and then irradiate with otherwise-harmless light (as opposed to dangerous things like x-rays). That avoids problems from liver accumulation, since the liver isn't irradiated. I'm not sure how far through testing it is at this point, though, and I'm not an expert - take with a grain of salt.

  • Great talk! This technology is a great advance in surgery.

  • she is hot

  • Another beautiful and brilliant Asian woman. I like this trend, TED.

  • This is Amazing and it is much needed. It should be added to the surgical techniques without even thinking about it!

  • Amazing work, great talk!

  • Where are our governments support on this, yeh "lets put man on a moon and beyond", costing billions of dollars!, but what about the millions who suffer daily with the anxiety, affect on the body and and emotions that cancer delivers not just to the patient but the loved ones. All tax payers without say on on where our governments spend our money........

    If this were oil exploration we would adopt this technology overnight.

    Well done(spoken) Quyen and all the best with further development

  • Can someone tell me what the second video clip is of? It looks kind of like a skin of a small creature and two lungs.

  • 2:39 Note to myself: "Do not eat while you are watching your weekly TEDtalks."

  • Amazing! hope this will get commercial support so that we get a fast release to market strategy and benefit from this great breakthrough!

  • Why dye? Why not a toxin to kill the cells?

  • @adolthitler Even better would be an antigen to attract antibodies.

  • @adolthitler There are some radiation therapies that are injected and target cancerous cells, notably thyroid cancer with Iodine-131. In the case of solid tumors, it might simply be faster to remove them surgically. Or, there may be trouble finding a toxin that only begins killing tissue where it "lands" (in the cancer cell), rather than everything it touches on its way through the bloodstream. But I bet they're working on it.

  • @adolthitler A coworker went to Dr. Tsien's talk and told me about this. Attaching a toxin instead of GFP/dye to the polycation-cleavable-polyanion complex is already being studied. The problem is the liver, like tumors, also produces many of the enzymes that can cleave. So the toxins will accumulate in the liver, which would be bad.

  • @maxwellsdaemon7 Iguess then liver cancer will still be a problem, even when tagged by dye.

  • Ahhh she's Vietnamese ! Go Quyen Nguyen we love u

  • she does a great job making it understandable.

  • This is really a breakthrough to cancer research. She must be supported by all the concerned bodies in the area.

  • i cant see it because im colorlind =/

  • Brilliant.

  • Transcript:15:18 I'd like to leave you this final thought, successful innovation is not a single break through, it is not a sprint, it is not an event for the solo runner, successful innovation is a team sport of a relay race, it requires one team to break through, another team to get that accepted and adopted, and this takes long term steady courages of day-in and day-out struggle to educate, to persuade and to win acceptance, that is the light that I would shine on health medicine today.

  • I wonder where the 3 dislikes came from...

  • @klingon13524 I wonder where the 3 dislikes came from...

    -they were tumours.

  • cô ấy đến từ VN :"> so proud

  • HD would be nice

  • I think breakthroughs like this are really great, but not to be taken as hope for a cure. Cancer occurs as a result of our body not being able to rid mutated cells from our body. Every single day our body disposes of mutated cells that have the potential to become cancer. The question should not be: how do we cut it out effectively?, but 'what makes this system fail and how do we prevent its failure?' We cannot smoke, drink, eat junk and prey that modern medicine will save us when we get sick...

  • Amazingly brilliant

  • Coloring in ... that's all it is .... dont deny it.

  • wow this is so amazing!

  • cancer is only a symptom of the standard western human diet. the shit we take in makes us feel shitty. then double shit comes out of us!

  • @molapft You should totally share your ideas on the international stage.

  • @TheSpeshulShark

    i know but them wont listen ;)

  • @molapft You have no idea about all the possible causes of cancer, do you? Unfortunately, going through life only eating nuts and berries won't keep you from getting cancer. Sure, eating healthy is important, but to say our diet is the 'only' cause of cancer is naive and misinformed!

  • @RudinBiology

    i didnt intended to make it look like diet is the only thing which causes cancer. (just trying to get people startled by such statements to get them rethink their habits) smoking, radiation, neat little additives put into all kinds of plastics and last but not least chance can cause cancer. not to forget viruses which some people suspect to cause e.g. womb cancer. me qualified my knowledge to you enough? ;)

  • oh, a talent from vietnam. i'm vietnamese person, too and i feel so proud of her

  • that is some light

  • ultrasound surgery is way cooler than this.

  • An astounding intelligence!

  • This is a great idea! A simple solution to a big problem, I love advancing technology and creative problem solvers.

  • It's a RELAY RACE. Wow. This woman is TERRIFIC. What a great talk. Gives me hope for the future of our own brand of "modern medicine," which I have avoided at all costs. Maybe I'll agree to go to the hospital one of these days "before I'm dead." I'd love to have this woman as my doctor.

  • If the Coke brothers really want to change the world, this is who they should be donating to!

  • @Lesserthannone But they don't want to change the world for the better.

  • Is she the VIetnamese ?

  • @darkknight21193 Yes, her name is the clue.

  • This is so fucking cool they should put this into every damn hospital asap holy shit this is awesome. this will change surgery.

  • No sucessful inovation starts with one man rising above is calluges and being sucessful but the parisite say its not fare and so he loses hope

  • This is why I'm pround to be a Vietnamese =]

  • I see robots in the future using this technology along with computer vision to localize specific organs and issues and then make an almost perfect surgery.

  • I love smart people

  • Did NOT want to see a beating heart. All for the message, but beating heart.

  • THIS IS AMAZING!!!!!

    

  • That's fantastic!!!

  • Now if we can only develop code to inject into the presentation that highlights the redundant (cancerous) parts of the talk and leaves us with the most interesting, remaining bits (the images and videos) behind.

  • Interesting. I did an internship at a company working on fluorescense imaging. They actually do the same thing they are here, but for biological research. Good to see technology from different fields leaking other into others in a good way.

  • Brilliant....

  • damn, she's fit.

    lucky husband ;)

    great talk!

    

  • take it to Canada, England, France...places with Universal healthcare, they actually care about their people. we need CHANGE!!!!!!

  • @valleyshrew go troll elsewhere.

  • @valleyshrew ....sounds like we have ourselves a faith-healer.

  • @valleyshrew

    *religious ignorance

  • @valleyshrew lol

  • If I were to give a TED talk I would be much less offended by the fact that the intro is slightly loud than I would be by all of the people obsessing about it instead of typing serious comments that pertain to the talk.

  • @mtdeezy : TED talks needs to respond to the intro and turn it down, so we CAN enjoy the talk and add "serious comments." No reason for TED Talks not to listen!

  • loved this

  • 11:49 - Crazy! xD

  • I wish we could convince our plumbers to use color coded water mains so they would stop mixing up our hot/cold lines.

  • Why not add a fourth part to these formulas? Why not add something that will kill tissue in which it is attached? If they could do this, this could be the 'cure' for cancer!

  • Not my favorite speaker. She has a very long introduction, which is barely to the point, and then describes a technology which sounds as if it had been developed by someone else (Roger Tsien?). Oh, wait, now I get why she blabbers about medicine being a team work...

  • so in other words big pharmaceutical companies are stopping this since there is less money in it because less people will need to take pills for an extended period of time?

  • simple, yet very impressive

  • I didn't even watch this video, but much thanks for changing the screenshot thumbnail from the picture that looked like a colored vagina.

  • @hddnwrd Why, do vaginas frighten you.

  • I heard Roger Tsien give this talk. He makes it sound way more cooler, but I guess his talk is geared towards scientists.

  • I dislike that she tried to contrive a moral, an act-structure in a talk the matter of which was itself compelling.

  • Wow...

  • If you have build a molecule which can track down a cancer cell so specific, why then have this molecule shine a color? Why not give it an actual poison, that will kill the cell? It seems strange to make such precise tracking, and then still remove it with big clumsy tools (compared to the tiny structures involved). Other than that, great!

  • @HKragh Because the tracking is not as specific as she makes it sound. It's still easier to just cut it out, once you have a ball park estimate of what its limits are.

  • @HKragh It'seasier said then done.

  • @HKragh A coworker went to Dr. Tsien's talk and told me about this. The problem is the liver, like tumors, also produces many of the enzymes that can cleave. So the poison/toxin will accumulate in the liver, which would be bad.

  • @cp9lol more like 1:00

  • It's too bad it's so hard to change minds for the better.

  • truly brilliant 

  • Gorgeous and brilliant. I think I want to marry her. :)

  • @tdurran You do that.

  • @vesji I think I've got competition. 11 likes on my comment. :(

  • @tdurran =D

  • @tdurran Too bad dude, she's married. Someone else had already put a ring on it. lol

  • @tdurran her finger has diamond ring n a band... i think she's married~ ;p

  • @nadzyhum D'oh! Me fail!

  • This should reduce malpractice insurance.

  • Color-Coded-Surgery - for the Nguyen.

  • @justforwatchingcraps We can already see tumor cells by using the same selectivity markers she used for the Fluorescent injection except we have a metal or other indicator in tow. MRI can read magnetic fields so near any safe metal is good. There will always be a use for physical surgeons. There are things or situations that ultrasound cannot help, I'm sure.

  • Bravo I hope this technology moves forward.

  • Amazing! Cute woman too

  • This is beautiful

    

  • Amazing; thanks!

  • This is fucking amazing

  • so that earlier talk on ultrasound destruction of tumor cells sort of competes with this method, i feel like the ultrasound method sort of makes this obsolete if they find away to visualize tumor cells on imaging

  • Can you please make it so I can glow all the time? That would be awesome! :D Just kidding. Interesting talk.

  • Please keep pushing forward! This is amazing! Thank you for this wonderful talk.

  • They are going to defeat cancer in this generation!

  • they've so far only tested it on rats?

    ... of course the prospects are illuring, but I'ld worry about an allergic reaktion.

  • ...but thats a rat.

  • wow!

  • Amazing.

  • I will something odd in my body watching those!

  • Very Very inspiring to listen to the great things people do in the world. This is definitely a big step in the right direction for surgeons. Great work and research.

  • is she from cambodia or vietnam?

  • @Bluemann

    Vietnam. 

  • Comment removed

  • damn this talk is crazy my nigga

  • what if the doc is daltonic?

  • Is her name pronounced "Win win"?

  • Astonishing, seriously

  • Wouldn't it be awesome if it could be combined with the ultrasound surgery somehow..

  • Nice. Her accent is cool too.

  • Science! Fuck yeah!

  • 12:00

  • This is amazing.

  • that is really impressive!

  • As always thanks!

  • 14:38... So how much do you want to bet it'll never fly on the basis that it will cause drops in profit for other drugs...

  • @iamufreak sometimes rich people get cancer too